| Assay ID | Title | Year | Journal | Article |
|---|
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347167 | Vero cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347152 | Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347168 | HepG2 cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347149 | Furin counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347153 | Confirmatory screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID165617 | In vitro antiplatelet activity against arachidonic acid induced malondialdehyde production | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID1423037 | Inhibition of human COX2 expressed in baculovirus infected sf21 cells assessed as reduction in formation of oxidized TMPD at 50 uM using arachidonic acid as substrate preincubated for 3 to 5 mins followed by arachidonic acid addition measured for 25 secs | 2018 | ACS medicinal chemistry letters, Oct-11, Volume: 9, Issue:10
| Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides. |
| AID1423032 | Inhibition of COX1 in human platelet microsomes assessed as reduction in formation of oxidized TMPD using arachidonic acid as substrate preincubated for 3 to 5 mins followed by arachidonic acid addition measured for 25 secs by spectrophotometric assay | 2018 | ACS medicinal chemistry letters, Oct-11, Volume: 9, Issue:10
| Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides. |
| AID76572 | Inhibitory effect on platelet aggregation induced by Collagen in guinea pigs ex vivo at a dose of 1 mg/Kg after 6 hr of oral administration | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID76573 | Inhibitory effect on platelet aggregation induced by Collagen in guinea pigs ex vivo at a dose of 3.2 mg/Kg after 6 hr of oral administration | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID76570 | Inhibitory effect on platelet aggregation induced by Arachidonic acid (AA) in guinea pigs ex vivo at a dose of 1 mg/kg after 6 hr of oral administration | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID177067 | Compound was evaluated for collagen-induced platelet aggregation ex vivo in rat at the dose of 100 mg/Kg | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID229998 | Induction of acute stomach lesion at a dose of 100 mg/Kg to determine the number of rats with ulceration; 0/5 | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID76571 | Inhibitory effect on platelet aggregation induced by Arachidonic acid (AA) in guinea pigs ex vivo at a dose of 3.2 mg/Kg after 6 hr of oral administration | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID176610 | In vitro vasodilatory activity in isolated rat aorta | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID196871 | Induction of acute stomach lesion at a dose of 100 mg/Kg | 1994 | Journal of medicinal chemistry, Apr-15, Volume: 37, Issue:8
| Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles. |
| AID328205 | Inhibition of COX1 | 2008 | Journal of medicinal chemistry, Apr-24, Volume: 51, Issue:8
| Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor. |
| AID328206 | Inhibition of COX2 | 2008 | Journal of medicinal chemistry, Apr-24, Volume: 51, Issue:8
| Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor. |
| AID1345284 | Human COX-1 (Cyclooxygenase) | 2000 | European journal of pharmacology, Mar-10, Volume: 391, Issue:1-2
| The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |