| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID367018 | Inhibition of [3H]glycine uptake at rat glycine transporter 1 expressed in african green monkey COS7 cells | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24
| New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). |
| AID308947 | Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cells | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
| Discovery and SAR studies of novel GlyT1 inhibitors. |
| AID1634028 | Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by scintillation spectroscopy | 2019 | ACS medicinal chemistry letters, Jun-13, Volume: 10, Issue:6
| Discovery of GlyT2 Inhibitors Using Structure-Based Pharmacophore Screening and Selectivity Studies by FEP+ Calculations. |
| AID367020 | Inhibition of [3H]glycine uptake in human T98G cells | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24
| New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). |
| AID1388362 | Inhibition of human GlyT-1 | 2018 | Journal of medicinal chemistry, 04-12, Volume: 61, Issue:7
| Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain. |
| AID639652 | Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillation counting | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21
| Synthesis and characterization of [¹²⁵I]2-iodo N-[(S)-{(S)-1-methylpiperidin-2-yl}(phenyl)methyl]3-trifluoromethyl-benzamide as novel imaging probe for glycine transporter 1. |
| AID1629932 | Competitive inhibition of glycine transporter-1 (unknown origin) expressed in HEK293 cells at 0.62 to 17 nM in presence of [3H]glycine by scintillation proximity assay | 2016 | Journal of medicinal chemistry, Sep-22, Volume: 59, Issue:18
| Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1. |
| AID367019 | Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24
| New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). |
| AID1634029 | Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by scintillation spectroscopy relative to untreated control | 2019 | ACS medicinal chemistry letters, Jun-13, Volume: 10, Issue:6
| Discovery of GlyT2 Inhibitors Using Structure-Based Pharmacophore Screening and Selectivity Studies by FEP+ Calculations. |
| AID1559416 | Inhibition of human GlyT1 expressed in QT6 cells assessed as reduction in [14C]glycine uptake incubated for 20 mins by liquid scintillation counting method | 2020 | Journal of medicinal chemistry, 04-23, Volume: 63, Issue:8
| The Druggability of Solute Carriers. |
| AID768449 | Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillation counting analysis | 2013 | Journal of medicinal chemistry, Jul-25, Volume: 56, Issue:14
| Atropisomeric 4-phenyl-4H-1,2,4-triazoles as selective glycine transporter 1 inhibitors. |
| AID1634027 | Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectroscopy | 2019 | ACS medicinal chemistry letters, Jun-13, Volume: 10, Issue:6
| Discovery of GlyT2 Inhibitors Using Structure-Based Pharmacophore Screening and Selectivity Studies by FEP+ Calculations. |
| AID241454 | Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors. |
| AID308948 | Increase in glycine level of Sprague-Dawley rat cerebrospinal fluid at 30 mg/kg, sc | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
| Discovery and SAR studies of novel GlyT1 inhibitors. |
| AID308949 | Drug level in rat cerebrospinal fluid at 30 mg/kg, sc | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
| Discovery and SAR studies of novel GlyT1 inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |