| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 7 | 0 | 0 | 7 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Phospholipase A2 isoform 3 | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
| ras protein, partial | 0 | 0 | 1 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| GLS protein | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 7 | 0 | 0 | 7 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| Rac1 protein | 0 | 0 | 1 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 4 | 0 | 0 | 4 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 7 | 0 | 7 |
| Multidrug resistance-associated protein 4 | 0 | 7 | 0 | 7 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 2 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 8 | 0 | 8 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 0 | 1 | 0 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 0 | 1 | 0 | 1 |
| Glutathione hydrolase 1 proenzyme | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 2 | 0 | 2 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Urotensin-2 receptor | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 1 | 1 | 4 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 7 | 0 | 7 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 1 | 3 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| nonstructural protein 1 | 4 | 0 | 0 | 4 |
| chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 4 | 0 | 0 | 4 |
| Cytochrome P450 2C8 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2B6 | 0 | 3 | 0 | 3 |
| Liver carboxylesterase 1 | 0 | 0 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 4 | 0 | 4 |
| Rap guanine nucleotide exchange factor 4 | 2 | 0 | 0 | 2 |
| P2Y purinoceptor 12 | 0 | 1 | 0 | 1 |
| Thromboxane A2 receptor | 0 | 1 | 1 | 2 |
| Prostaglandin E2 receptor EP1 subtype | 0 | 1 | 1 | 2 |
| Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 0 | 1 |
| Prostaglandin F2-alpha receptor | 0 | 2 | 1 | 3 |
| Prostaglandin E2 receptor EP3 subtype | 0 | 1 | 1 | 2 |
| Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 0 | 1 |
| Prostacyclin receptor | 0 | 1 | 0 | 1 |
| Prostaglandin D2 receptor | 0 | 1 | 0 | 1 |
| Cereblon isoform 4 | 0 | 2 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
| Insulin-like growth factor-binding protein 5 | 0 | 0 | 1 | 1 |
| Choline O-acetyltransferase | 0 | 1 | 0 | 1 |
| Protein cereblon | 0 | 2 | 0 | 2 |
| Luciferase | 2 | 0 | 0 | 2 |
| progesterone receptor | 5 | 0 | 0 | 5 |
| pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Solute carrier family 22 member 8 | 0 | 1 | 0 | 1 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| G | 3 | 0 | 0 | 3 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 2 | 2 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
| Glucocorticoid receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 3 | 0 | 0 | 3 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 3 | 0 | 0 | 3 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| Parkin | 1 | 0 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit beta-4 | 0 | 1 | 0 | 1 |
| Voltage-dependent P/Q-type calcium channel subunit alpha-1A | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1G | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-3 subunit | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 1 | 2 |
| Voltage-dependent T-type calcium channel subunit alpha-1H | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Cannabinoid receptor 1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit beta-3 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-7 subunit | 0 | 1 | 0 | 1 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit beta-1 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-1 subunit | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit beta-2 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 1 | 2 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | 0 | 1 | 0 | 1 |
| Voltage-dependent R-type calcium channel subunit alpha-1E | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-4 | 0 | 1 | 0 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | 0 | 0 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-3 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-8 subunit | 0 | 1 | 0 | 1 |
| Bile acid receptor | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-6 subunit | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-2 | 0 | 1 | 0 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1I | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-4 subunit | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-5 subunit | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 0 | 1 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3E | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Carboxypeptidase M | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 4 | 2 | 6 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 2 | 1 | 4 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 1E | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3C | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 1 | 3 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 1 | 3 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 1 | 3 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 1 | 3 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 1 | 3 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 0 | 1 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-1 adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |