a-130a and Disease-Models--Animal

a-130a has been researched along with Disease-Models--Animal* in 1 studies

Other Studies

1 other study(ies) available for a-130a and Disease-Models--Animal

Article	Year
Antiinflammatory constituents from Heterotheca inuloides. Journal of natural products, 2001, Volume: 64, Issue:7 Three new compounds, cadalen-15-oic acid (1), 3,7-dihydroxy-3(4H)-isocadalen-4-one (2), and dicadalenol (3), were isolated from the aerial parts of Heterotheca inuloides (Mexican arnica), together with the known compounds 7-hydroxycadalene (4), 7-hydroxy-4alphaH-3,4-dihydrocadalene (5), 1alpha-hydroxy-1(4H)-isocadalen-4-one (6), 1alpha-hydroxy-4alphaH-1,2,3,4-tetrahydrocadalen-15-oic acid (7), 7-(3,3-dimethylallyloxy)coumarin, caryolan-1,9beta-diol, and quercetin. The structures of the new compounds were elucidated by spectroscopic methods. The antiinflammatory activities of the extracts and the isolated compounds were evaluated by determining the inhibition of TPA-induced mouse ear edema. The natural products 3, caryolan-1,9beta-diol, and quercetin were the most active substances tested and displayed dose-dependent activities. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asteraceae; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Flavonoids; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mexico; Mice; Naphthalenes; Plant Leaves; Plant Stems; Plants, Medicinal; Quercetin; Tetradecanoylphorbol Acetate	2001

Article

Year

Antiinflammatory constituents from Heterotheca inuloides.

Journal of natural products, 2001, Volume: 64, Issue:7

Three new compounds, cadalen-15-oic acid (1), 3,7-dihydroxy-3(4H)-isocadalen-4-one (2), and dicadalenol (3), were isolated from the aerial parts of Heterotheca inuloides (Mexican arnica), together with the known compounds 7-hydroxycadalene (4), 7-hydroxy-4alphaH-3,4-dihydrocadalene (5), 1alpha-hydroxy-1(4H)-isocadalen-4-one (6), 1alpha-hydroxy-4alphaH-1,2,3,4-tetrahydrocadalen-15-oic acid (7), 7-(3,3-dimethylallyloxy)coumarin, caryolan-1,9beta-diol, and quercetin. The structures of the new compounds were elucidated by spectroscopic methods. The antiinflammatory activities of the extracts and the isolated compounds were evaluated by determining the inhibition of TPA-induced mouse ear edema. The natural products 3, caryolan-1,9beta-diol, and quercetin were the most active substances tested and displayed dose-dependent activities.

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asteraceae; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Flavonoids; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mexico; Mice; Naphthalenes; Plant Leaves; Plant Stems; Plants, Medicinal; Quercetin; Tetradecanoylphorbol Acetate

2001