Page last updated: 2024-09-28

Transmissible Venereal Tumors

Tumors most commonly seen on or near the genitalia. They are venereal, most likely transmitted through transplantation of cells by contact. Metastases have been reported. Spontaneous regression may occur.

Synonyms(6)

Synonym
Veterinary Venereal Tumors
Tumors, Transmissible Venereal
Tumors, Veterinary Venereal
Venereal Tumors, Veterinary
Venereal Tumors, Transmissible
Transmissible Venereal Tumors

Research Excerpts

Research

Studies (37)

TimeframeStudies, This Condition (%)All Conditions %
pre-199014 (37.84)23.3326
1990's4 (10.81)12.5806
2000's10 (27.03)18.1394
2010's7 (18.92)28.8240
2020's2 (5.41)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetic acid0low20
nickel0low10
oxalic acid0low10
busulfan0low10
hydralazine0low10
prednisolone0low10
idoxuridine0low10
nitrilotriacetic acid0low10
transferrin0low20
methotrexate0low20
depsidomycin0low10
maleic acid0low10
bromochloroacetic acid0low20
phenylephrine hydrochloride0low10
gallium0low10
oxalates0low10
dextrothyroxine0medium11
s-tetradecanoyl-coenzyme a0low20
oligonucleotides0low10
transforming growth factor beta0low40
cyclosporine0low10
muramidase0low30
chondroitin sulfates0low10
concanavalin a0low10

Protein Targets (315)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
estrogen nuclear receptor alpha9009
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Fibrinogen C domain-containing protein 10101
RAR-related orphan receptor gamma4004
AR protein7007
aldehyde dehydrogenase 1 family, member A15005
nuclear receptor subfamily 1, group I, member 34004
retinoic acid nuclear receptor alpha variant 18008
thyroid stimulating hormone receptor2002
nuclear factor erythroid 2-related factor 2 isoform 19009
Cellular tumor antigen p535005
Nuclear receptor ROR-gamma1001
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, 2-oxoglutarate Oxygenase4004
15-lipoxygenase, partial2002
TDP1 protein6006
apical membrane antigen 1, AMA12002
thyroid stimulating hormone receptor4004
cytochrome P450 family 3 subfamily A polypeptide 42002
EWS/FLI fusion protein3003
glucocorticoid receptor [Homo sapiens]5005
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha8008
pregnane X nuclear receptor4004
aryl hydrocarbon receptor2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
thyroid hormone receptor beta isoform 23003
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
geminin8008
lethal factor (plasmid)1001
lamin isoform A-delta106006
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40405
Bile salt export pump0505
Matrix metalloproteinase-90101
Disintegrin and metalloproteinase domain-containing protein 171001
Canalicular multispecific organic anion transporter 10404
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Ferritin light chain2002
Chain A, Cruzipain1001
endonuclease IV2002
thioredoxin reductase5005
Microtubule-associated protein tau3003
nonstructural protein 12002
glucocerebrosidase1001
Bloom syndrome protein isoform 13003
peripheral myelin protein 22 isoform 12002
potassium voltage-gated channel subfamily H member 2 isoform d1001
DNA polymerase beta2002
mitogen-activated protein kinase 11001
DNA polymerase iota isoform a (long)4004
M-phase phosphoprotein 82002
neuropeptide S receptor isoform A1001
Spike glycoprotein3003
Cereblon isoform 40202
GLI family zinc finger 35005
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase2002
interleukin 81001
acetylcholinesterase1001
glp-1 receptor, partial2002
Skn7p0001
pregnane X receptor2002
hypoxia-inducible factor 1 alpha subunit2002
ATAD5 protein, partial3003
Thrombopoietin2002
estrogen receptor 2 (ER beta)2002
progesterone receptor5005
farnesoid X nuclear receptor2002
67.9K protein3003
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma4004
arylsulfatase A2002
IDH13003
euchromatic histone-lysine N-methyltransferase 24004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x2002
hemoglobin subunit beta1001
chromobox protein homolog 14004
nuclear factor erythroid 2-related factor 2 isoform 23003
huntingtin isoform 21001
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Vpr3003
peripheral myelin protein 224004
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 12002
Voltage-dependent calcium channel gamma-2 subunit3003
Solute carrier family 22 member 80001
Epidermal growth factor receptor0101
Amyloid-beta precursor protein1001
Thymidylate synthase0303
Aromatase0101
Glutamate receptor 23003
ATPase family AAA domain-containing protein 54004
Ataxin-25005
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
ATP-dependent phosphofructokinase2002
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
phosphopantetheinyl transferase2002
GLS protein1001
Parkin1001
pyruvate kinase1001
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a3003
ras-related protein Rab-9A1001
nuclear receptor ROR-gamma isoform 11001
cytochrome P450 3A4 isoform 11001
muscarinic acetylcholine receptor M11001
pyruvate kinase PKM isoform b1001
Gamma-aminobutyric acid receptor subunit pi1001
N-glycosylase/DNA lyase0101
Integrin beta-33003
Myeloperoxidase0101
Integrin alpha-IIb3003
Ornithine decarboxylase1001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit beta-11001
Aspartate aminotransferase, cytoplasmic0101
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Lactoperoxidase0101
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
Single-stranded DNA cytosine deaminase1001
Thymidine kinase 0101
importin subunit beta-1 isoform 12002
snurportin-12002
Thymidine kinase, cytosolic0101
Thymidine phosphorylase0001
Thymidine kinase0001
TAR DNA-binding protein 432002
Chain A, Aspartate Aminotransferase0011
Chain B, Aspartate Aminotransferase0011
Chain A, Aspartate Aminotransferase0011
Chain B, Aspartate Aminotransferase0011
Chain A, Aspartate aminotransferase0011
Chain B, Aspartate aminotransferase0011
Chain A, Aspartate aminotransferase0011
Chain A, Aspartate aminotransferase0011
Chain A, Aspartate aminotransferase0011
Chain B, Aspartate aminotransferase0011
transcriptional regulator ERG isoform 32002
Interferon beta2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
USP1 protein, partial1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
vitamin D3 receptor isoform VDRA1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA polymerase kappa isoform 11001
histone acetyltransferase KAT2A isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Carbonic anhydrase 20011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
nonstructural protein 10101
thyroid hormone receptor beta isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
serine/threonine-protein kinase PLK11001
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Pyruvate kinase, M2 isozyme0101
Chain A, Phosphonopyruvate hydrolase0101
Chain A, Phosphoenolpyruvate-protein phosphotransferase0101
Proto-oncogene tyrosine-protein kinase Src0101
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
luciferase0001
nuclear receptor subfamily 1, group I, member 21001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0101
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]