Page last updated: 2024-09-27

Mastocytoma, Skin

A variant of cutaneous mastocytosis which occurs as a single lesion usually in infants. It is found mostly in the wrist and trunk and there is no atypical cytomorphology.

Synonyms(3)

Synonym
Skin Mastocytoma
Mastocytoma, Skin
Solitary Mastocytoma of Skin

Research

Studies (15)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's2 (13.33)18.1394
2010's11 (73.33)28.8240
2020's2 (13.33)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
histamine0low10
hydroxyurea0medium11
prednisolone0low10
methylprednisolone0low10
tolonium chloride0low10
betamethasone0low10
fluorescein0low10
triamcinolone0low10
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide0low10
imatinib mesylate0low20
betamethasone-17,21-dipropionate0low10
mupirocin0low10
dinoprostone0low10
desonide0low10
interleukin-80low10

Protein Targets (308)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
pregnane X receptor2002
GLI family zinc finger 37007
AR protein110011
progesterone receptor8008
cytochrome P450 family 3 subfamily A polypeptide 45005
glucocorticoid receptor [Homo sapiens]100010
estrogen-related nuclear receptor alpha100010
farnesoid X nuclear receptor6006
pregnane X nuclear receptor100010
estrogen nuclear receptor alpha110011
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
IDH14004
aryl hydrocarbon receptor6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
nuclear receptor subfamily 1, group I, member 24004
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 24004
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 17007
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40506
Voltage-dependent calcium channel gamma-2 subunit4004
Bile salt export pump0808
Glucocorticoid receptor08114
Glycine receptor subunit alpha-10808
Glutamate receptor 24004
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Canalicular multispecific organic anion transporter 10505
ORF730011
SMAD family member 25005
SMAD family member 35005
TDP1 protein6006
retinoic acid nuclear receptor alpha variant 18008
peroxisome proliferator-activated receptor delta3003
ATPase family AAA domain-containing protein 55005
Ataxin-25005
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Cruzipain1001
thyroid stimulating hormone receptor3003
regulator of G-protein signaling 42002
retinoid X nuclear receptor alpha6006
thyroid stimulating hormone receptor4004
activating transcription factor 62002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
prostaglandin E2 receptor EP2 subtype1001
vitamin D3 receptor isoform VDRA2002
thyroid hormone receptor beta isoform 25005
mitogen-activated protein kinase 11001
geminin7007
peripheral myelin protein 221001
Solute carrier family 22 member 20002
Solute carrier family 22 member 1 0002
Solute carrier organic anion transporter family member 1A50001
Cellular tumor antigen p535005
Cytochrome P450 3A40012
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60102
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200202
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain1001
acetylcholinesterase5005
hypoxia-inducible factor 1 alpha subunit3003
Microtubule-associated protein tau1001
estrogen receptor 2 (ER beta)3003
peroxisome proliferator activated receptor gamma1001
euchromatic histone-lysine N-methyltransferase 25005
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Bloom syndrome protein isoform 13003
heat shock protein beta-13003
DNA polymerase kappa isoform 11001
histone acetyltransferase KAT2A isoform 12002
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
Chain A, Beta-lactamase1001
aryl hydrocarbon receptor nuclear translocator0001
thioredoxin reductase5005
phosphopantetheinyl transferase1001
USP1 protein, partial1001
GALC protein1001
GLS protein2002
apical membrane antigen 1, AMA12002
EWS/FLI fusion protein2002
bromodomain adjacent to zinc finger domain 2B3003
potassium voltage-gated channel subfamily H member 2 isoform d1001
transforming acidic coiled-coil-containing protein 30001
DNA polymerase iota isoform a (long)2002
lamin isoform A-delta104004
Carbonic anhydrase 120102
Solute carrier family 22 member 30102
Carbonic anhydrase 10203
Carbonic anhydrase 20306
Plasma kallikrein0001
Carbonic anhydrase 30102
Macrophage migration inhibitory factor0202
Carbonic anhydrase 40203
Carbonic anhydrase 60102
Histamine H2 receptor0123
Adenosine receptor A10001
5-hydroxytryptamine receptor 1D0001
Adenosine receptor A2a0001
Histamine H1 receptor0134
Histamine H1 receptor0213
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0203
Histamine H1 receptor0224
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase 70102
Histamine H2 receptor0011
Carbonic anhydrase0002
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90204
Carbonic anhydrase 0002
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0002
Carbonic anhydrase0002
Glutamate receptor ionotropic, NMDA 2D0001
Solute carrier family 22 member 10102
Carbonic anhydrase 0002
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3B0001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40001
Carbonic anhydrase 150102
Carbonic anhydrase 130102
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20102
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Histamine H3 receptor0123
Fumarate hydratase2002
NFKB1 protein, partial2002
polyprotein2002
Histone H2A.x2002
peripheral myelin protein 22 isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
cytochrome P450 3A4 isoform 12002
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit pi2002
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10022
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-12002
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit gamma-22002
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Inositol monophosphatase 11001
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
GABA theta subunit2002
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit epsilon2002
Gamma-aminobutyric acid receptor subunit theta0101
Luciferase2002
glp-1 receptor, partial2002
nuclear receptor subfamily 1, group I, member 33003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
serine/threonine-protein kinase mTOR isoform 11001
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10112
Cytochrome P450 2C80001
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
Spike glycoprotein2002
PPM1D protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
nonstructural protein 11001
G2002
muscleblind-like protein 1 isoform 12002
Nuclear receptor subfamily 1 group I member 20011
Interferon beta4004
HLA class I histocompatibility antigen, B alpha chain 2002
Androgen receptor0303
Inositol hexakisphosphate kinase 12002
Nuclear receptor subfamily 1 group I member 20011
cytochrome P450 2C9, partial2002
ATP-dependent phosphofructokinase1001
Chain A, Isoleucyl-tRNA synthetase0101
heat shock protein 900011
streptokinase A precursor0011
twin arginine protein translocation system - TatA protein0001
Isoleucine--tRNA ligase0101
Estrogen receptor0011
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0101
TAR DNA-binding protein 431001
Estrogen receptor beta0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
RAR-related orphan receptor gamma4004
serine-protein kinase ATM isoform a1001
chromobox protein homolog 12002
lethal(3)malignant brain tumor-like protein 1 isoform I1001
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20202
Estrogen receptor beta0202
Chain A, 2-oxoglutarate Oxygenase1001
chaperonin-containing TCP-1 beta subunit homolog1001
aldehyde dehydrogenase 1 family, member A11001
survival motor neuron protein isoform d1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0101
Albumin0101
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
cytochrome P450 2D61001
histone deacetylase 9 isoform 31001
Microtubule-associated protein tau0202
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
ATAD5 protein, partial1001
thioredoxin glutathione reductase1001
Smad31001
arylsulfatase A1001
procathepsin L isoform 1 preproprotein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]