disulfiram [no description available] | 3.25 | 1 | 0 | organic disulfide; organosulfur acaricide | angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 3.1.1.1 (carboxylesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; ferroptosis inducer; fungicide; NF-kappaB inhibitor |
flurbiprofen Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.. flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain. | 2.08 | 1 | 0 | fluorobiphenyl; monocarboxylic acid | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
hexadecanesulfonyl fluoride AM 374: a palmitylsulfonyl fluoride; inhibits anandamide amidase; structure given in first source | 3.25 | 1 | 0 | acyl fluoride | |
ethylmaleimide Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies. | 3.25 | 1 | 0 | maleimides | anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor |
carbaryl Carbaryl: A carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries.. carbaryl : A carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid. | 3.16 | 1 | 0 | carbamate ester; naphthalenes | acaricide; agrochemical; carbamate insecticide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant growth retardant |
diphenyl disulfide [no description available] | 3.25 | 1 | 0 | benzenes | |
diacerein diacerein: chelates with bivalent metals; a quinone which possesses redox properties; metabolized to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases; called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase; | 3.25 | 1 | 0 | anthraquinone | |
2-n-octyl-4-isothiazolin-3-one octhilinone : A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union. | 3.25 | 1 | 0 | 1,2-thiazoles | antibacterial agent; antifungal agrochemical; environmental contaminant; xenobiotic |
efegatran efegatran: RN & structure given in first source; RN given refers to parent cpd (D)-isomer | 3.14 | 1 | 0 | | |
ono 6818 ONO 6818: structure in first source | 3.14 | 1 | 0 | | |
urb 597 cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester: a fatty acid amide hydrolase inhibitor; structure in first source | 4.39 | 3 | 0 | biphenyls | |
jnj-1661010 [no description available] | 3.16 | 1 | 0 | N-arylpiperazine | |
anandamide anandamide : An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. | 3.25 | 1 | 0 | endocannabinoid; N-acylethanolamine 20:4 | human blood serum metabolite; neurotransmitter; vasodilator agent |
glyceryl 2-arachidonate glyceryl 2-arachidonate: binds to cannabinoid receptors; structure in first source. 2-arachidonoylglycerol : An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol. | 3.25 | 1 | 0 | 2-acylglycerol 20:4; endocannabinoid | human metabolite |
benzoyl-norleucyl-lysyl-arginyl-arginal [no description available] | 3.14 | 1 | 0 | | |
cay 10499 [no description available] | 3.25 | 1 | 0 | carbamate ester | |
urb 524 [no description available] | 4.11 | 2 | 0 | | |
ol-135 [no description available] | 4.71 | 3 | 0 | | |
urb602 URB602: inhibitor of 2-arachidonoylglycerol (2-AG)-deactivating enzyme, monoacylglycerol lipase, structure in first source | 3.25 | 1 | 0 | | |
ly2183240 LY2183240: structure in first source | 4.11 | 2 | 0 | biphenyls | |
methylphenidate N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide: a fatty acid amide hydrolase inhibitor; structure in first source | 3.25 | 1 | 0 | | |
am 6701 [no description available] | 3.25 | 1 | 0 | | |
compstatin compstatin: binds to complement 3; amino acid sequence in first source | 3.14 | 1 | 0 | | |
pf 3845 PF 3845: inhibits fatty acid amide hydrolase | 3.25 | 1 | 0 | piperidines | |
pf 750 N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide: a fatty acid amide hydrolase inhibitor; structure in first source | 3.25 | 1 | 0 | quinolines | |
jzl195 JZL195: inhibits both fatty-acid amide hydrolase 1 and monoglyceride lipase; structure in first source | 2.08 | 1 | 0 | | |
urb937 URB937: a peripherally restricted inhibitor of fatty acid amide hydrolase | 3.25 | 1 | 0 | | |
sar127303 SAR127303: inhibits monoacylglycerol lipase; structure in first source | 3.25 | 1 | 0 | | |
mjn110 MJN110: structure in first source | 3.25 | 1 | 0 | | |