carvone, (s)-isomer profile

(+)-carvone : A carvone having (S) configuration. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	16724
CHEMBL ID	501949
CHEBI ID	15399
SCHEMBL ID	184022
MeSH ID	M0309750

Synonyms (91)

Synonym
d-carvone
(5s)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one
(5s)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one
(+)-(4s)-carvone
(s)-5-isopropenyl-2-methylcyclohex-2-en-1-one
(s)-(+)-carvone
(s)-(+)-p-mentha-6,8-dien-2-one
(4s)-p-mentha-1(6),8-dien-2-one
CHEBI:15399 ,
(s)-carvone
(s)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one
d-(+)-carvone
(s)-2-methyl-5-(1-methylvinyl)cyclohex-2-en-1-one
2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (s)-
p-mentha-6,8-dien-2-one, (s)-(+)-
d-p-mentha-6,8,(9)-dien-2-one
d-1-methyl-4-isopropenyl-6-cyclohexen-2-one
(5s)-2-methyl-5-(1-methylethenyl)cyclohex-2-en-1-one
ai3-39004
d(+)-carvone
einecs 218-827-2
carvone, (+)-
2-cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5s)-
(s)-d-p-mentha-6,8,(9)-dien-2-one
ccris 2385
d-carvone (natural)
NCGC00091882-01
(+)-carvone
(+)-(s)-carvone
carvol
2244-16-8
(s)-(+)-carvone, 96%
d-carvone, >=96%, fg
NCGC00091882-03
NCGC00091882-02
s-(+)-carvone
(4s)-carvone
MLS002415723
smr001370898
(5s)-2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one
CHEMBL501949
s(+)-carvone
NCGC00091882-04
HMS3039E10
unii-4rwc1cms3x
4rwc1cms3x ,
dtxcid00256
dtxsid8020256 ,
NCGC00256315-01
tox21_302743
cas-2244-16-8
(5s)-2-methyl-5-(1-methylvinyl)cyclohex-2-en-1-one
NCGC00258992-01
tox21_201441
A816212
(s)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enone
0wu ,
EPITOPE ID:141510
AM84798
carvone, d-
carvone d-
(+)-carvone [fcc]
fema no. 2249, (+)-
carvone d-form [mi]
S6049
SCHEMBL184022
Q-200930
d-p-mentha-6,8(9)-dien-2-one
5-isopropenyl-2-methyl-2-cyclohexen-1-one, (s)-
mfcd00062997
(s)-5-isopropenyl-2-methyl-2-cyclohexenone
(+)-carvone, certified reference material, tracecert(r)
talent
(+)-carvone, analytical standard
CS-W014295
s-carvone
d-carvon
DS-4662
Q27889969
HY-W013579
(+)carvone
(s)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one
EN300-393032
AKOS016843871
d-carvone 2-methyl-5-(1-methylethenyl)-2-cyclohexene-1-one
2-methyl-4-(1 -methylethenyl)-2-cyclohexene-1 -one
O10215
d-carvol
carvone d-form
Z1255356261
d-?carvone

Excerpt	Relevance	Reference
" All EOs were repellent, followed a dose-response relationship, and had bioactivity similar to or better than that of commercial compound IR3535."	( Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst. Caballero-Gallardo, K; Olivero-Verbel, J; Stashenko, EE, 2011)	0.37

Class	Description
carvone	A p-menthane monoterpenoid that consists of cyclohex-2-enone having methyl and isopropenyl substituents at positions 2 and 5, respectively.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathway	Proteins	Compounds
Olfactory Signaling Pathway	80	28
(4S)-carvone biosynthesis	1	16
Sensory Perception	215	68
(4S)-carveol and (4S)-dihydrocarveol degradation	2	31

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
GLI family zinc finger 3	Homo sapiens (human)	Potency	2.4783	0.0007	14.5928	83.7951	AID1259369
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	25.2855	0.0112	12.4002	100.0000	AID1030
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	8.4368	0.5318	15.4358	37.6858	AID504845
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	40.5600	0.0002	29.3054	16,493.5996	AID1259244; AID743075
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	0.0178	0.0100	39.5371	1,122.0200	AID588547
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	18.8336	0.0006	27.2152	1,122.0200	AID651741
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	68.5896	0.0015	57.7890	15,848.9004	AID1259244
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	68.5896	0.0015	51.7393	15,848.9004	AID1259244
Nuclear receptor ROR-gamma	Homo sapiens (human)	Potency	0.0596	0.0266	22.4482	66.8242	AID651802
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	17.7828	1.7783	16.2081	35.4813	AID652104
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
negative regulation of transcription by RNA polymerase II	Nuclear receptor ROR-gamma	Homo sapiens (human)
xenobiotic metabolic process	Nuclear receptor ROR-gamma	Homo sapiens (human)
regulation of glucose metabolic process	Nuclear receptor ROR-gamma	Homo sapiens (human)
regulation of steroid metabolic process	Nuclear receptor ROR-gamma	Homo sapiens (human)
intracellular receptor signaling pathway	Nuclear receptor ROR-gamma	Homo sapiens (human)
circadian regulation of gene expression	Nuclear receptor ROR-gamma	Homo sapiens (human)
cellular response to sterol	Nuclear receptor ROR-gamma	Homo sapiens (human)
positive regulation of circadian rhythm	Nuclear receptor ROR-gamma	Homo sapiens (human)
regulation of fat cell differentiation	Nuclear receptor ROR-gamma	Homo sapiens (human)
positive regulation of DNA-templated transcription	Nuclear receptor ROR-gamma	Homo sapiens (human)
adipose tissue development	Nuclear receptor ROR-gamma	Homo sapiens (human)
T-helper 17 cell differentiation	Nuclear receptor ROR-gamma	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Nuclear receptor ROR-gamma	Homo sapiens (human)
negative regulation of protein phosphorylation	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA processing	TAR DNA-binding protein 43	Homo sapiens (human)
RNA splicing	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of protein stability	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of insulin secretion	TAR DNA-binding protein 43	Homo sapiens (human)
response to endoplasmic reticulum stress	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of protein import into nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of circadian rhythm	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of apoptotic process	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation by host of viral transcription	TAR DNA-binding protein 43	Homo sapiens (human)
rhythmic process	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of cell cycle	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA destabilization	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear inner membrane organization	TAR DNA-binding protein 43	Homo sapiens (human)
amyloid fibril formation	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nuclear receptor ROR-gamma	Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specific	Nuclear receptor ROR-gamma	Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specific	Nuclear receptor ROR-gamma	Homo sapiens (human)
DNA-binding transcription factor activity	Nuclear receptor ROR-gamma	Homo sapiens (human)
protein binding	Nuclear receptor ROR-gamma	Homo sapiens (human)
oxysterol binding	Nuclear receptor ROR-gamma	Homo sapiens (human)
zinc ion binding	Nuclear receptor ROR-gamma	Homo sapiens (human)
ligand-activated transcription factor activity	Nuclear receptor ROR-gamma	Homo sapiens (human)
sequence-specific double-stranded DNA binding	Nuclear receptor ROR-gamma	Homo sapiens (human)
nuclear receptor activity	Nuclear receptor ROR-gamma	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
double-stranded DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
RNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA 3'-UTR binding	TAR DNA-binding protein 43	Homo sapiens (human)
protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
lipid binding	TAR DNA-binding protein 43	Homo sapiens (human)
identical protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
pre-mRNA intronic binding	TAR DNA-binding protein 43	Homo sapiens (human)
molecular condensate scaffold activity	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
plasma membrane	Glutamate receptor 2	Rattus norvegicus (Norway rat)
nucleus	Nuclear receptor ROR-gamma	Homo sapiens (human)
nucleoplasm	Nuclear receptor ROR-gamma	Homo sapiens (human)
nuclear body	Nuclear receptor ROR-gamma	Homo sapiens (human)
chromatin	Nuclear receptor ROR-gamma	Homo sapiens (human)
nucleus	Nuclear receptor ROR-gamma	Homo sapiens (human)
intracellular non-membrane-bounded organelle	TAR DNA-binding protein 43	Homo sapiens (human)
nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
perichromatin fibrils	TAR DNA-binding protein 43	Homo sapiens (human)
mitochondrion	TAR DNA-binding protein 43	Homo sapiens (human)
cytoplasmic stress granule	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear speck	TAR DNA-binding protein 43	Homo sapiens (human)
interchromatin granule	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
chromatin	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (27)

Assay ID	Title	Year	Journal	Article
AID1081891	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID360823	Growth inhibition of cellular yeast form of Candida albicans H317 at 5 mM after 2 hrs	2002	Journal of natural products, Jul, Volume: 65, Issue:7	Carvone and perillaldehyde interfere with the serum-induced formation of filamentous structures in Candida albicans at substantially lower concentrations than those causing significant inhibition of growth.
AID1081887	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081892	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081885	Lipophilicity, logP of the compound	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081894	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081890	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081889	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081895	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081886	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID360821	Anticandidal activity against Candida albicans H317 assessed as inhibition of transformation of organism from cellular yeast to filamentous form at 250 uM preincubated for 2 hrs before addition of fetal bovine serum measured after 22 hrs by phase contrast	2002	Journal of natural products, Jul, Volume: 65, Issue:7	Carvone and perillaldehyde interfere with the serum-induced formation of filamentous structures in Candida albicans at substantially lower concentrations than those causing significant inhibition of growth.
AID1081893	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID360824	Effect on growth of cellular yeast form of Candida albicans H317 at lower concentration after 2 hrs	2002	Journal of natural products, Jul, Volume: 65, Issue:7	Carvone and perillaldehyde interfere with the serum-induced formation of filamentous structures in Candida albicans at substantially lower concentrations than those causing significant inhibition of growth.
AID1081888	Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation	2011	Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5	Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (28.57)	29.6817
2010's	4 (57.14)	24.3611
2020's	1 (14.29)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
benzyl benzoate benzyl benzoate: structure; acarosan, a moist powder composed of wetted cellulose and benzyl benzoate, is used on carpets as an acaricide. benzyl benzoate : A benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol. It has been isolated from the plant species of the genus Polyalthia.	2.06	1	benzoate ester; benzyl ester	acaricide; plant metabolite; scabicide
4-cymene 4-cymene: structure. p-cymene : A monoterpene that is toluene substituted by an isopropyl group at position 4.	2.06	1	monoterpene; toluenes	human urinary metabolite; plant metabolite; volatile oil component
benzyl salicylate benzyl salicylate: structure given in Merck	2.06	1	benzoate ester; phenols
citronellol citronellol: alcohol form of citronellal; found in rose oil; RN given refers to parent cpd without isomeric designation; structure. citronellol : A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.. insect repellent : An insecticide that acts as a repellent to insects.	2.06	1	monoterpenoid	plant metabolite
carvacrol carvacrol : A phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1).	2.06	1	botanical anti-fungal agent; p-menthane monoterpenoid; phenols	agrochemical; antimicrobial agent; flavouring agent; TRPA1 channel agonist; volatile oil component
myrcene myrcene: structure in first source. beta-myrcene : A monoterpene that is octa-1,6-diene bearing methylene and methyl substituents at positions 3 and 7 respectively.	2.06	1	monoterpene	anabolic agent; anti-inflammatory agent; flavouring agent; fragrance; plant metabolite; volatile oil component
ethyl-3-(n-n-butyl-n-acetyl)aminopropionate ethyl-3-(N-n-butyl-N-acetyl)aminopropionate: an insect repellent; structure in first source	2.06	1	acetamides; ethyl ester; tertiary carboxamide
geraniol [no description available]	2.06	1	3,7-dimethylocta-2,6-dien-1-ol; monoterpenoid; primary alcohol	allergen; fragrance; plant metabolite; volatile oil component
citral citral: Xref geranial: geraniol is also available; Xref neral: nerol is also available; vitamin A antagonist; oxygenated monoterpene; inhibits cytosolic dehydrogenases; structure. citral : An enal that consists of octa-2,6-dienal bearing methyl substituents at positions 3 and 7. A mixture of the two geometric isomers geranial and neral, it is the major constituent (75-85%) of oil of lemon grass, the volatile oil of Cymbopogon citratus, or of C. flexuosus. It also occurs in oils of verbena, lemon, and orange.	2.06	1	enal; monoterpenoid; polyprenal	plant metabolite; volatile oil component
nerol nerol : The (2Z)-stereoisomer of 3,7-dimethylocta-2,6-dien-1-ol. It has been isolated from the essential oils from plants like lemon grass.	2.06	1	3,7-dimethylocta-2,6-dien-1-ol	fragrance; plant metabolite; volatile oil component
geranyl acetate geranyl acetate: constituted about 90% of the palmarosa oil. geranyl acetate : A monoterpenoid that is the acetate ester derivative of geraniol.	2.06	1	acetate ester; monoterpenoid	plant metabolite

Condition	Indicated	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	0	2.05	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	2.05	1	0

carvone, (s)-isomer

Description

Cross-References

Synonyms (91)

Research Excerpts

Dosage Studied

Drug Classes (1)

Pathways (4)

Protein Targets (10)

Potency Measurements

Biological Processes (31)

Molecular Functions (18)

Ceullar Components (11)

Bioassays (27)

Research

Studies (7)

Market Indicators

Research Demand Index: 12.20

Study Types

carvone, (s)-isomer

Description

Cross-References

Synonyms (91)

Research Excerpts

Dosage Studied

Drug Classes (1)

Pathways (4)

Protein Targets (10)

Potency Measurements

Biological Processes (31)

Molecular Functions (18)

Ceullar Components (11)

Bioassays (27)

Research

Studies (7)

Market Indicators

Research Demand Index: 12.20

Study Types

Related Drugs (11)

Related Conditions (2)