Compounds > beta-asarone
Page last updated: 2024-11-10

beta-asarone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

beta-asarone : The cis-isomer of asarone. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID5281758
CHEMBL ID477752
CHEBI ID10353
CHEBI ID78308
CHEBI ID68146
SCHEMBL ID528747
MeSH IDM0311780

Synonyms (62)

Synonym
benzene, 1,2,4-trimethoxy-5-(1-propenyl)-, (z)-
asarone, (z)-isomer
cis-isoelemicin
cis-isoasarone
2,4,5-trimethoxypropen-1-ylbenzene
einecs 226-096-6
ai3-36897
benzene, 1,2,4-trimethoxy-5-propenyl-, (z)-
ccris 1592
(z)-1,2,4-trimethoxy-5-(1-propenyl)benzene
(z)-5-propenyl-1,2,4-trimethoxybenzene
(z)-asarone
brn 1910605
beta-asarone
(z)-1-(2,4,5-trimethoxyphenyl)-1-propene
cis-asarone
5273-86-9
cis-2,4,5-trimethoxy-1-propenylbenzene, 70%
CHEMBL477752
chebi:10353 ,
cis-asaron
1,2,4-trimethoxy-5-[(z)-prop-1-enyl]benzene
1,2,4-trimethoxy-5-propenylbenzene, z-
S9118
unii-iga3mh6iuw
3-06-00-06440 (beilstein handbook reference)
iga3mh6iuw ,
cis-2,4,5-trimethoxy-1-propenylbenzene
benzene, 1,2,4-trimethoxy-5-(1z)-1-propenyl-
.beta.-asarone, cis-
.beta.-asarone
cis-.beta.-asarone
benzene, 1,2,4-trimethoxy-5-(1z)-1-propen-1-yl-
SCHEMBL528747
CHEBI:78308
beta-asaron
cis-2,4,5-trimethoxyphenylpropene
1,2,4-trimethoxy-5-[(1z)-prop-1-en-1-yl]benzene
W-105801
(z)-.beta.-asarone
1,2,4-trimethoxy-5-[(1z)-1-propenyl]benzene
AC-34897
chebi:68146
CS-W009103
AKOS030524038
mfcd00009281
1,2,4-trimethoxy-5-((z)-1-propenyl)benzene, ?-asarone
beta-asarone, primary pharmaceutical reference standard
beta-asarone; 1,2,4-trimethoxy-5-[(z)-prop-1-enyl]benzene; ?-asarone
A870918
DS-9662
i(2)-asarone
(z)-1 pound not2 pound not4-trimethoxy-5-(1-propenyl)benzene
BCP23722
Q27089385
DTXSID601020057 ,
HMS3886B18
HY-N1501
CCG-266642
1,2,4-trimethoxy-5-((1z)-prop-1-en-1-yl)benzene
beta-asarone, cis-
dtxcid00911420
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
GABA modulatorA substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
asaroneA phenylpropanoid that is benzene substituted by methoxy groups at positions 1, 2 and 4 and a propen-1-yl group at position 5. It has been isolated from Acorus.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (35)

Assay IDTitleYearJournalArticle
AID1102644Antimicrobial activity against Cladosporium cucumerinum assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102645Antimicrobial activity against Alternaria mali assessed as mycelial growth inhibition at 100 ug/ml after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID611613Allosteric modulation of rat gamma-aminobutyric acid receptor A alpha1beta2gamma2S expressed in Xenopus oocytes assessed as potentiation of GABA-mediated chloride current after 20 secs by voltage clamp assay2011Journal of natural products, Jun-24, Volume: 74, Issue:6
Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling.
AID1102643Antimicrobial activity against Colletotrichum orbiculare assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID611612Allosteric modulation of rat gamma-aminobutyric acid receptor A alpha1beta2gamma2S expressed in Xenopus oocytes assessed as potentiation of GABA-mediated chloride current at 0.1 to 1000 uM after 20 secs by voltage clamp assay2011Journal of natural products, Jun-24, Volume: 74, Issue:6
Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling.
AID1102627Antifungal activity against Colletotrichum orbiculare infested cucumber plant grown under greenhouse condition assessed as supression of anthracnose development at 500 ug/ml sprayed at two-leaf stage 1 day prior inoculation measured after 6 days post inoc2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102633Antimicrobial activity against Pectobacterium carotovorum subsp. carotovorum assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1080378Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 0.4 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102626Antifungal activity against Magnaporthe grisea infested rice plant grown under greenhouse condition assessed as reduction in lesion formation on second leaves at 100 ug/ml sprayed at eight-leaf stage 1 day prior inoculation measured after 5 days post inoc2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102636Antimicrobial activity against Bacillus subtilis assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID733737Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay2013European journal of medicinal chemistry, Apr, Volume: 62Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: structure-activity relationship.
AID1102632Antimicrobial activity against Ralstonia solanacearum assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102625Antifungal activity against Magnaporthe grisea infested rice plant grown under greenhouse condition assessed as reduction in lesion formation on second leaves at 500 ug/ml sprayed at eight-leaf stage 1 day prior inoculation measured after 5 days post inoc2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1080377Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 0.6 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102635Antimicrobial activity against Sclerotinia sclerotiorum assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID332623Larvicidal activity against Aedes aegypti larvae after 24 hrs by TLC bioassay1995Journal of natural products, Jan, Volume: 58, Issue:1
Isolation of antifungal and larvicidal constituents of Diplolophium buchanani by centrifugal partition chromatography.
AID1102629Antifungal activity against Colletotrichum orbiculare infested cucumber plant grown under greenhouse condition assessed as reduction in lesion formation on second leaves at 500 ug/ml sprayed at two-leaf stage 1 day prior inoculation measured after 6 days 2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102640Antimicrobial activity against Phytophthora capsici assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID734142Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay2013European journal of medicinal chemistry, Apr, Volume: 62Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: structure-activity relationship.
AID1102638Antimicrobial activity against Pythium ultimum assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID488646Induction of cAMP level in mouse NIE115 cells at 50 uM after 30 mins by Alphascreen cAMP assay2010Journal of natural products, Jun-25, Volume: 73, Issue:6
Compounds from Acorus tatarinowii: determination of absolute configuration by quantum computations and cAMP regulation activity.
AID733739Cytotoxicity against human SW982 cells assessed as growth inhibition after 72 hrs by MTT assay2013European journal of medicinal chemistry, Apr, Volume: 62Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: structure-activity relationship.
AID1080379Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 0.8 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102641Antimicrobial activity against Fusarium oxysporum f. sp. lycopersici assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1080376Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 0.2 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102631Antimicrobial activity against Saccharomyces cerevisiae assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102642Antimicrobial activity against Ilyonectria radicicola assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102639Antimicrobial activity against Magnaporthe grisea assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1080381Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 2 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102634Antimicrobial activity against Candida albicans assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID379656Larvicidal activity against Aedes aegypti assessed as drug level required to kill instar II larvae after 24 hrs2000Journal of natural products, Mar, Volume: 63, Issue:3
Antifungal and larvicidal compounds from the root bark of Cordia alliodora.
AID1102646Antimicrobial activity against Botryotinia fuckeliana assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1102630Antimicrobial activity against Xanthomonas euvesicatoria assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
AID1080380Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 1 mg/mL measured 24 hr post dose by microscopy2008Journal of agricultural and food chemistry, Aug-27, Volume: 56, Issue:16
Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), Oriental sweetgum (Liquidambar orientalis), and valerian (Valeriana wallichii) essential oils against pine wood nematode (Bursaphelenchus xylophilus).
AID1102637Antimicrobial activity against Rhizoctonia solani assessed as mycelial growth inhibition after 3 to 5 days2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Antifungal activity of beta-asarone from rhizomes of Acorus gramineus.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 37.27

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index37.27 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index46.22 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (37.27)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzaldehyde
[no description available]		2.0410benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
benzyl alcohol
Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.. hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.. benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.. aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.. aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.		2.0410benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
caprylic aldehyde
caprylic aldehyde: structure in Merck Index, 9th ed, #1765. octanal : A saturated fatty aldehyde formally arising from reduction of the carboxy group of caprylic acid (octanoic acid).		2.0410medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		plant metabolite
clotiazepam
clotiazepam: was heading 1975-94 (see under AZEPINES 1978-90; was Y 6047 see under AZEPINES 1975-77); Y 6047 was see CLOTIAZEPAM 1978-94; use AZEPINES to search CLOTIAZEPAM 1975-94; thienodiazepine derivative with actions similar to those of benzodiazepines		2.0610organic molecular entity
miconazole
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.. 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.. miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.		1.9810dichlorobenzene;
ether;
imidazoles
midazolam
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.. midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.		2.0610imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
myristicin
myristicin: asaricin is an isomer; structure; a methylene dioxy version of elemicin;		1.9810organic molecular entitymetabolite
triazolam
Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.		2.0610triazolobenzodiazepinesedative
methylphenyl carbinol
1-phenylethanol : An aromatic alcohol that is ethanol substituted by a phenyl group at position 1.. methylbenzyl alcohol : Members of the class of benzyl alcohols substituted by at least one methyl group.		2.0410aromatic alcoholmouse metabolite
acetophenone
acetophenone : A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.		2.0410acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
styrene
Styrene: A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.. styrene : A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species.		2.0410styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
heptanal
heptanal : An n-alkanal resulting from the oxidation of the alcoholic hydroxy group of heptan-1-ol to the corresponding aldehyde. An endogenous aldehyde coming from membrane lipid oxidation, it is found in the blood of lung cancer patients and has been regarded as a potential biomarker of lung cancer.		2.0410medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		biomarker
nonane
iotrochotin: toxin from the Caribbean sponge Iotrochota birotulata, which selectively permeabilizes synaptosomes. nonane : A straight chain alkane composed of 9 carbon atoms.		2.0410alkaneplant metabolite;
volatile oil component
n-decyl alcohol
n-decyl alcohol: RN given refers to parent cpd. decanol : A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of ten carbon atoms.. decan-1-ol : A fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of ten carbon atoms.		2.0410decanol;
primary alcohol		metabolite;
pheromone;
protic solvent
decanaldehyde
decanal : A saturated fatty aldehyde formally arising from reduction of the carboxy group of capric acid (decanoic acid).		2.0410medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		antifungal agent;
fragrance;
plant metabolite
undecanal
undecanal : A saturated fatty aldehyde formally arising from reduction of the carboxylic acid group of undecanoic acid. It is a component of essential oils from citrus plants like Citrus reticulata.		2.0410medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		antimycobacterial drug;
plant metabolite;
volatile oil component
plumbagin
plumbagin: a superoxide anion generator. plumbagin : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively.		210hydroxy-1,4-naphthoquinone;
phenols		anticoagulant;
antineoplastic agent;
immunological adjuvant;
metabolite
d-alpha tocopherol
Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.		2.0810alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
tetrachloroisophthalonitrile
tetrachloroisophthalonitrile: structure. chlorothalonil : A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops.		2.0210aromatic fungicide;
dinitrile;
tetrachlorobenzene		antifungal agrochemical
aviprin
aviprin: isolated from Angelica dahurica; structure in first source		1.9810furanocoumarinmetabolite
2,4,5-trimethoxybenzaldehyde
asaronaldehyde: from Piper clusii (Piperaceae); structure in first source		2.0510carbonyl compound
3-phenyl-1-propanol
[no description available]		2.0410monocyclic arene
nonanal
nonanal : A saturated fatty aldehyde formally arising from reduction of the carboxy group of nonanoic acid. Metabolite observed in cancer metabolism.		2.0410medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		human metabolite;
plant metabolite
oxypeucadanin, (s)-(-)-isomer
[no description available]		1.9810epoxide;
furanocoumarin;
lactone		plant metabolite
tricyclazole
tricyclazole: RN given refers to parent cpd. tricyclazole : A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union.		2.0210triazolobenzothiazoleantifungal agrochemical;
melanin synthesis inhibitor
celastrol methyl ester
celastrol methyl ester: isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME		2.0810carboxylic ester
alpha-asarone
asarone: structure in Merck Index, 9th ed, #847. asarone : A phenylpropanoid that is benzene substituted by methoxy groups at positions 1, 2 and 4 and a propen-1-yl group at position 5. It has been isolated from Acorus.. alpha-asarone : The trans-isomer of asarone.		2.4520asaroneanticonvulsant;
GABA modulator
geranyl acetate
geranyl acetate: constituted about 90% of the palmarosa oil. geranyl acetate : A monoterpenoid that is the acetate ester derivative of geraniol.		2.0410acetate ester;
monoterpenoid		plant metabolite
(2e)-decenal
(2E)-decenal: structure in first source. (2E)-dec-2-enal : A dec-2-enal in which the olefinic double bond has E configuration.		2.04102-decenalalarm pheromone;
mutagen;
nematicide
cinnamyl alcohol
cinnamyl alcohol: RN given refers to parent cpd without isomeric designation. (E)-cinnamyl alcohol : The E (trans) stereoisomer of cinnamyl alcohol.. cinnamyl alcohol : A primary alcohol comprising an allyl core with a hydroxy substituent at the 1-position and a phenyl substituent at the 3-position (geometry of the C=C bond unspecified).		2.0410cinnamyl alcoholplant metabolite
valerenic acid
valerenic acid: a saturated oplopanone type indene from Valeriana officinalis. valerenic acid : A monocarboxylic acid that is 2-methylprop-2-enoic acid which is substituted at position 3 by a 3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl group. A bicyclic sesquiterpenoid constituent of the essential oil of the Valerian plant.		2.0610carbobicyclic compound;
monocarboxylic acid;
sesquiterpenoid		GABA modulator;
plant metabolite;
sedative;
volatile oil component
nystatin a1
Nystatin: Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3.. nystatin : A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections.. nystatin A1 : A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.		210nystatins
ascorbic acid
Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.. L-ascorbic acid : The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.. L-ascorbate : The L-enantiomer of ascorbate and conjugate base of L-ascorbic acid, arising from selective deprotonation of the 3-hydroxy group. Required for a range of essential metabolic reactions in all animals and plants.. vitamin C : Any member of a group of vitamers that belong to the chemical structural class called butenolides that exhibit biological activity against vitamin C deficiency in animals. The vitamers include L-ascorbic acid and its salt, ionized and oxidized forms.		2.0810ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
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