Page last updated: 2024-12-09

nerol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

nerol : The (2Z)-stereoisomer of 3,7-dimethylocta-2,6-dien-1-ol. It has been isolated from the essential oils from plants like lemon grass. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID643820
CHEMBL ID452683
CHEBI ID29452
SCHEMBL ID19825
MeSH IDM0051260

Synonyms (83)

Synonym
nsc-46105
neryl alcohol
cis-3,7-dimethyl-2,6-octadien-1-ol
(2z)-3,7-dimethyl-2,6-octadien-1-ol
2-cis-3,7-dimethyl-2,6-octadien-1-ol
(z)-3,7-dimethyl-2,6-octadien-1-ol
(z)-geraniol
CHEBI:29452 ,
3,7-dimethyl-2,6-octadien-1-ol, cis-
ai3-28202
3,7-dimethyl-2,6-octadien-1-ol, (z)-
einecs 203-378-7
nerol (natural)
fema no. 2770
cis-geraniol
2,6-octadien-1-ol, 3,7-dimethyl-, (z)-
3,7-dimethyl-2,6-octadien-1-ol
3,7-dimethylocta-2,6-dien-1-ol
2,6-octadien-1-ol, 3,7-dimethyl-, (2z)-
(2z)-3,7-dimethylocta-2,6-dien-1-ol
106-25-2
C09871
nerol
(z)-3,7-dimethylocta-2,6-dien-1-ol
cis-3,7-dimethyl-2,6-octadien-1-ol, >=97%, fcc, fg
cis-3,7-dimethyl-2,6-octadien-1-ol, 97%
NCGC00164117-01
z-geraniol
LMPR0102010010
CHEMBL452683
N0077
A801400
(2z)-3,7-dimethyl-1-octa-2,6-dienol
NCGC00164117-02
NCGC00164117-03
(2z)-3,7-dimethyl-octa-2,6-dien-1-ol
dtxcid806728
tox21_300542
dtxsid3026728 ,
cas-106-25-2
tox21_202029
NCGC00254346-01
NCGC00259578-01
AKOS016008578
unii-38g5p53250
nerol 900
38g5p53250 ,
hsdb 8262
ec 203-378-7
S4970
SCHEMBL19825
nerol [fhfi]
nerol [fcc]
nerol [mi]
(z)-nerol
.beta.-nerol
cis-2,6-dimethyl-2,6-octadien-8-ol
(2z)-3,7-dimethyl-2,6-octadien-1-ol #
W-108769
mfcd00063204
bdbm50036946
nerol, analytical standard
3,7-dimethyl-octane-1-ol tetrahydro derivative
(z)3,7-dimethyl-2,6-octadien-1-ol
(2e)3,7-dimethyl-2,6-octadien-1-ol
(2z)3,7-dimethyl-2,6-octadien-1-ol
(e)3,7-dimethyl-2,6-octadien-1-ol
vernol
(e)3,7-dimethyl-octadien-1-ol
3,7-dimethyl-trans-2, 6-octadien-1-ol
AS-61707
nerol 1000 microg/ml in isopropanol
3,7-dimethyl-2z,6-octadien-1-ol
CS-W018031
HY-N7063
(cis)3,7-dimethyl-2,6-octadien-1-ol
Q415359
HMS3886M07
CCG-266252
D70365
3,7-dimethyl-octa-2cis,6-dien-1-ol
NZZ ,
EN300-817771

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" All EOs were repellent, followed a dose-response relationship, and had bioactivity similar to or better than that of commercial compound IR3535."( Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
Caballero-Gallardo, K; Olivero-Verbel, J; Stashenko, EE, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (3)

RoleDescription
volatile oil componentAny plant metabolite that is found naturally as a component of a volatile oil.
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
fragranceA substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
3,7-dimethylocta-2,6-dien-1-ol
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (2)

PathwayProteinsCompounds
nerol biosynthesis06
geraniol and nerol degradation011

Protein Targets (6)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
farnesoid X nuclear receptorHomo sapiens (human)Potency0.00350.375827.485161.6524AID588526
pregnane X nuclear receptorHomo sapiens (human)Potency19.46890.005428.02631,258.9301AID1346982
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency26.00520.000323.4451159.6830AID743065; AID743066
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)IC50 (µMol)100.00000.45003.42437.5000AID1173731
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)IC50 (µMol)100.00000.00020.606010.0000AID1173737
Transient receptor potential cation channel subfamily M member 8Rattus norvegicus (Norway rat)IC50 (µMol)100.00000.05802.65048.3000AID1173734
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)EC50 (µMol)11.70000.06002.22238.4000AID1173730
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (37)

Processvia Protein(s)Taxonomy
thermoceptionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of transcription by RNA polymerase IITransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
fever generationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
microglial cell activationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
diet induced thermogenesisTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
peptide secretionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of systemic arterial blood pressureTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
lipid metabolic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cell surface receptor signaling pathwayTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of cytosolic calcium ion concentrationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
chemosensory behaviorTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of heart rateTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of mitochondrial membrane potentialTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
glutamate secretionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium-mediated signalingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to heatTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of apoptotic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
response to peptide hormoneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
positive regulation of nitric oxide biosynthetic processTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
behavioral response to painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
sensory perception of mechanical stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of temperature stimulus involved in thermoceptionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
detection of chemical stimulus involved in sensory perception of painTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
protein homotetramerizationTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
excitatory postsynaptic potentialTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
smooth muscle contraction involved in micturitionTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium ion transmembrane transportTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to alkaloidTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to ATPTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to tumor necrosis factorTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to acidic pHTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to temperature stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
negative regulation of establishment of blood-brain barrierTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium ion import across plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
response to capsazepineTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
cellular response to nerve growth factor stimulusTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (15)

Processvia Protein(s)Taxonomy
transmembrane signaling receptor activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
extracellular ligand-gated monoatomic ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
excitatory extracellular ligand-gated monoatomic ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
voltage-gated calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
protein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
calmodulin bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
ATP bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
intracellularly gated calcium channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
chloride channel regulator activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
phosphatidylinositol bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
identical protein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
metal ion bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
phosphoprotein bindingTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
temperature-gated ion channel activityTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (6)

Processvia Protein(s)Taxonomy
plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
external side of plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
dendritic spine membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
neuronal cell bodyTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
postsynaptic membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
plasma membraneTransient receptor potential cation channel subfamily V member 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (34)

Assay IDTitleYearJournalArticle
AID1081893Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1081888Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID344009Antiproliferative activity against human HL60 cells by WST-1 assay2008Bioorganic & medicinal chemistry letters, Jul-15, Volume: 18, Issue:14
Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
AID1173735Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID338302Acaricidal activity against Psoroptes cuniculi at 1 uL after 24 hrs by inhalation assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID1081894Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID344010Antiproliferative activity against human HL60 cells at 400 uM by WST-1 assay2008Bioorganic & medicinal chemistry letters, Jul-15, Volume: 18, Issue:14
Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
AID1173736Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1173732Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to ionomycin2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081890Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081886Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173733Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1173731Antagonist activity against rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1070521Antimicrobial activity against Mycobacterium tuberculosis H37Rv by BACTEC radiometric assay2014Journal of natural products, Mar-28, Volume: 77, Issue:3
Airborne antituberculosis activity of Eucalyptus citriodora essential oil.
AID1173729Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry relative to AITC2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081892Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID338301Acaricidal activity against Psoroptes cuniculi at 3 uL after 24 hrs by inhalation assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID1081891Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.2 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081885Lipophilicity, logP of the compound2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1173734Antagonist activity against rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID338298Acaricidal activity against Psoroptes cuniculi at 0.25% dilution in physiological saline after 48 hrs by direct contact assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID1173737Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID344008Antiproliferative activity against human PC3 cells assessed as reduction of cell viability at 400 uM after 72 hrs by WST-1 assay2008Bioorganic & medicinal chemistry letters, Jul-15, Volume: 18, Issue:14
Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
AID338297Acaricidal activity against Psoroptes cuniculi at 1% dilution in physiological saline after 48 hrs by direct contact assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID344007Antiproliferative activity against human PC3 cells assessed as reduction of cell viability after 72 hrs by WST-1 assay relative to control2008Bioorganic & medicinal chemistry letters, Jul-15, Volume: 18, Issue:14
Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
AID1081895Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 2 hr post compound exposure at 0.00002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID1081887Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.02 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID338300Acaricidal activity against Psoroptes cuniculi at 6 uL after 24 hrs by inhalation assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID1173730Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluorimetry2014Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
AID1081889Repellent activity against Tribolium castaneum (red flour beetle) assessed as induction of repellency measured 4 hr post compound exposure at 0.0002 uL/cm2 using 15% compound formulation2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Repellent activity of essential oils and some of their individual constituents against Tribolium castaneum herbst.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID338299Acaricidal activity against Psoroptes cuniculi at 0.125% dilution in physiological saline after 48 hrs by direct contact assay1995Journal of natural products, Aug, Volume: 58, Issue:8
Structure/activity relationship of some natural monoterpenes as acaricides against Psoroptes cuniculi.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 51.55

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index51.55 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index5.21 (4.65)
Search Engine Demand Index145.75 (26.88)
Search Engine Supply Index3.86 (0.95)

This Compound (51.55)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (14.29%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]