Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain E, Purine nucleoside phosphorylase | 0 | 1 | 0 | 1 |
Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
Thymidine kinase | 0 | 1 | 0 | 1 |
thioredoxin reductase | 2 | 0 | 0 | 2 |
phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
GLS protein | 2 | 0 | 0 | 2 |
TDP1 protein | 7 | 0 | 0 | 7 |
Smad3 | 1 | 0 | 0 | 1 |
thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
EWS/FLI fusion protein | 4 | 0 | 0 | 4 |
arylsulfatase A | 3 | 0 | 0 | 3 |
euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
activating transcription factor 6 | 3 | 0 | 0 | 3 |
Histone H2A.x | 3 | 0 | 0 | 3 |
Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
hemoglobin subunit beta | 2 | 0 | 0 | 2 |
atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
ubiquitin carboxyl-terminal hydrolase 2 isoform a | 2 | 0 | 0 | 2 |
lamin isoform A-delta10 | 8 | 0 | 0 | 8 |
Solute carrier family 22 member 1 | 0 | 0 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 7 | 0 | 7 |
Multidrug resistance-associated protein 4 | 0 | 7 | 0 | 7 |
Solute carrier family 22 member 6 | 0 | 0 | 0 | 1 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Bile salt export pump | 0 | 8 | 0 | 8 |
Purine nucleoside phosphorylase | 0 | 1 | 0 | 1 |
Thymidine kinase, cytosolic | 0 | 0 | 0 | 1 |
POU domain, class 2, transcription factor 2 | 0 | 0 | 0 | 1 |
Cytochrome P450 2C9 | 0 | 5 | 0 | 6 |
Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
Disintegrin and metalloproteinase domain-containing protein 17 | 2 | 0 | 0 | 2 |
Purine nucleoside phosphorylase | 0 | 0 | 1 | 1 |
Solute carrier family 22 member 6 | 0 | 0 | 0 | 1 |
Thymidine kinase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 8 | 0 | 0 | 0 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 7 | 0 | 7 |
Thymidine kinase | 0 | 1 | 0 | 1 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
interleukin 8 | 4 | 0 | 0 | 4 |
glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
tumor necrosis factor | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 7 | 0 | 0 | 7 |
peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
Cytochrome P450 1A2 | 0 | 2 | 0 | 3 |
Cytochrome P450 3A4 | 0 | 4 | 0 | 5 |
Cytochrome P450 2D6 | 0 | 2 | 0 | 3 |
Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
Nuclear receptor ROR-gamma | 5 | 0 | 0 | 5 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
Aurora kinase B | 0 | 1 | 0 | 1 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
acetylcholinesterase | 2 | 0 | 0 | 2 |
RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
ATAD5 protein, partial | 1 | 0 | 0 | 1 |
Fumarate hydratase | 2 | 0 | 0 | 2 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
AR protein | 5 | 0 | 0 | 5 |
thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
retinoic acid nuclear receptor alpha variant 1 | 8 | 0 | 0 | 8 |
retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
estrogen-related nuclear receptor alpha | 7 | 0 | 0 | 7 |
pregnane X nuclear receptor | 7 | 0 | 0 | 7 |
estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
G | 3 | 0 | 0 | 3 |
polyprotein | 2 | 0 | 0 | 2 |
P53 | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
IDH1 | 2 | 0 | 0 | 2 |
aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 4 | 0 | 0 | 4 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
peripheral myelin protein 22 isoform 1 | 2 | 0 | 0 | 2 |
cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
thyroid hormone receptor beta isoform 2 | 6 | 0 | 0 | 6 |
heat shock protein beta-1 | 2 | 0 | 0 | 2 |
DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
geminin | 5 | 0 | 0 | 5 |
survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
cytochrome P450 3A4 isoform 1 | 4 | 0 | 0 | 4 |
M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 4 | 0 | 0 | 4 |
Voltage-dependent calcium channel gamma-2 subunit | 4 | 0 | 0 | 4 |
Interferon beta | 6 | 0 | 0 | 6 |
HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
Gamma-aminobutyric acid receptor subunit beta-1 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit delta | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 4 | 0 | 0 | 4 |
Glutamate receptor 2 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit beta-3 | 4 | 0 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit beta-2 | 4 | 0 | 0 | 4 |
GABA theta subunit | 4 | 0 | 0 | 4 |
Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
Ataxin-2 | 3 | 0 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit epsilon | 4 | 0 | 0 | 4 |
Protein-arginine deiminase type-4 | 0 | 2 | 0 | 2 |
cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
PPM1D protein | 2 | 0 | 0 | 2 |
5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
Spike glycoprotein | 2 | 0 | 1 | 3 |
Nonstructural protein 5A | 0 | 1 | 1 | 2 |
Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
apical membrane antigen 1, AMA1 | 2 | 0 | 0 | 2 |
aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 6 | 0 | 0 | 6 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
lethal factor (plasmid) | 2 | 0 | 0 | 2 |
Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
Chain A, BCL-2-RELATED PROTEIN A1 | 0 | 0 | 1 | 1 |
cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
unnamed protein product | 0 | 1 | 0 | 1 |
chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
bcl-2-like protein 11 isoform 1 | 0 | 0 | 1 | 1 |
Histone deacetylase 3 | 0 | 1 | 0 | 1 |
Rap guanine nucleotide exchange factor 3 | 2 | 0 | 0 | 2 |
Chymotrypsinogen A | 0 | 1 | 0 | 1 |
Beta-lactamase | 0 | 1 | 0 | 1 |
Steroid 17-alpha-hydroxylase/17,20 lyase | 0 | 1 | 0 | 1 |
Heme oxygenase 1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 1 | 1 | 2 |
Aromatase | 0 | 1 | 0 | 1 |
Cytochrome P450 11B1, mitochondrial | 0 | 1 | 0 | 1 |
Cytochrome P450 11B2, mitochondrial | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Heme oxygenase 2 | 0 | 1 | 0 | 1 |
Malate dehydrogenase, cytoplasmic | 0 | 1 | 0 | 1 |
Histone deacetylase 4 | 0 | 1 | 0 | 1 |
Cytochrome P450 144 | 0 | 0 | 2 | 2 |
Steroid C26-monooxygenase | 0 | 0 | 2 | 2 |
Steroid C26-monooxygenase | 0 | 0 | 2 | 2 |
Mycocyclosin synthase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
Histone deacetylase 1 | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 1 | 1 | 2 |
Sterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
Sterol 14-alpha demethylase | 0 | 1 | 1 | 2 |
Histone deacetylase 7 | 0 | 1 | 0 | 1 |
Histone deacetylase 2 | 0 | 1 | 0 | 1 |
Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
Histone deacetylase 11 | 0 | 1 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 1 | 1 |
Histone deacetylase 8 | 0 | 1 | 0 | 1 |
Histone deacetylase 6 | 0 | 1 | 0 | 1 |
Histone deacetylase 9 | 0 | 1 | 0 | 1 |
Histone deacetylase 5 | 0 | 1 | 0 | 1 |
heat shock protein 90, putative | 0 | 0 | 0 | 1 |
likely tRNA 2'-phosphotransferase | 0 | 1 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
GALC protein | 1 | 0 | 0 | 1 |
estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
30S ribosomal protein S6 | 0 | 2 | 0 | 2 |
30S ribosomal protein S7 | 0 | 2 | 0 | 2 |
50S ribosomal protein L15 | 0 | 2 | 0 | 2 |
50S ribosomal protein L10 | 0 | 2 | 0 | 2 |
50S ribosomal protein L11 | 0 | 2 | 0 | 2 |
50S ribosomal protein L7/L12 | 0 | 2 | 0 | 2 |
50S ribosomal protein L19 | 0 | 2 | 0 | 2 |
50S ribosomal protein L1 | 0 | 2 | 0 | 2 |
50S ribosomal protein L20 | 0 | 2 | 0 | 2 |
50S ribosomal protein L27 | 0 | 2 | 0 | 2 |
50S ribosomal protein L28 | 0 | 2 | 0 | 2 |
50S ribosomal protein L29 | 0 | 2 | 0 | 2 |
50S ribosomal protein L31 | 0 | 2 | 0 | 2 |
50S ribosomal protein L31 type B | 0 | 2 | 0 | 2 |
50S ribosomal protein L32 | 0 | 2 | 0 | 2 |
50S ribosomal protein L33 | 0 | 2 | 0 | 2 |
50S ribosomal protein L34 | 0 | 2 | 0 | 2 |
50S ribosomal protein L35 | 0 | 2 | 0 | 2 |
50S ribosomal protein L36 | 0 | 2 | 0 | 2 |
30S ribosomal protein S10 | 0 | 2 | 0 | 2 |
30S ribosomal protein S11 | 0 | 2 | 0 | 2 |
30S ribosomal protein S12 | 0 | 2 | 0 | 2 |
30S ribosomal protein S13 | 0 | 2 | 0 | 2 |
30S ribosomal protein S16 | 0 | 2 | 0 | 2 |
30S ribosomal protein S18 | 0 | 2 | 0 | 2 |
30S ribosomal protein S19 | 0 | 2 | 0 | 2 |
30S ribosomal protein S20 | 0 | 2 | 0 | 2 |
30S ribosomal protein S2 | 0 | 2 | 0 | 2 |
30S ribosomal protein S3 | 0 | 2 | 0 | 2 |
30S ribosomal protein S4 | 0 | 2 | 0 | 2 |
30S ribosomal protein S5 | 0 | 2 | 0 | 2 |
30S ribosomal protein S8 | 0 | 2 | 0 | 2 |
30S ribosomal protein S9 | 0 | 2 | 0 | 2 |
50S ribosomal protein L13 | 0 | 2 | 0 | 2 |
50S ribosomal protein L14 | 0 | 2 | 0 | 2 |
50S ribosomal protein L16 | 0 | 2 | 0 | 2 |
50S ribosomal protein L23 | 0 | 2 | 0 | 2 |
30S ribosomal protein S15 | 0 | 2 | 0 | 2 |
50S ribosomal protein L17 | 0 | 2 | 0 | 2 |
50S ribosomal protein L21 | 0 | 2 | 0 | 2 |
50S ribosomal protein L30 | 0 | 2 | 0 | 2 |
50S ribosomal protein L6 | 0 | 2 | 0 | 2 |
30S ribosomal protein S14 | 0 | 2 | 0 | 2 |
30S ribosomal protein S17 | 0 | 2 | 0 | 2 |
30S ribosomal protein S1 | 0 | 2 | 0 | 2 |
50S ribosomal protein L18 | 0 | 2 | 0 | 2 |
50S ribosomal protein L2 | 0 | 2 | 0 | 2 |
50S ribosomal protein L3 | 0 | 2 | 0 | 2 |
50S ribosomal protein L24 | 0 | 2 | 0 | 2 |
50S ribosomal protein L4 | 0 | 2 | 0 | 2 |
50S ribosomal protein L22 | 0 | 2 | 0 | 2 |
50S ribosomal protein L5 | 0 | 2 | 0 | 2 |
30S ribosomal protein S21 | 0 | 2 | 0 | 2 |
50S ribosomal protein L25 | 0 | 2 | 0 | 2 |
50S ribosomal protein L36 2 | 0 | 2 | 0 | 2 |
Tyrosyl-DNA phosphodiesterase 1 | 0 | 1 | 0 | 1 |
luciferase | 0 | 0 | 0 | 1 |
progesterone receptor | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
Estrogen receptor | 0 | 2 | 0 | 2 |
Glucocorticoid receptor | 0 | 4 | 2 | 11 |
Progesterone receptor | 0 | 2 | 0 | 3 |
Glucocorticoid receptor | 0 | 1 | 1 | 2 |
Glucocorticoid receptor | 0 | 0 | 1 | 1 |
Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
Androgen receptor | 0 | 2 | 0 | 2 |
Glutamine synthetase | 0 | 0 | 1 | 1 |
Androgen receptor | 0 | 1 | 0 | 1 |
Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
Histamine H1 receptor | 0 | 0 | 1 | 1 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
Nociceptin receptor | 0 | 0 | 1 | 1 |
Estrogen receptor beta | 0 | 2 | 0 | 2 |
pregnane X receptor | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
Glutamate 5-kinase | 0 | 0 | 0 | 1 |
Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
Amino acid transporter | 0 | 1 | 0 | 1 |
NS5 | 0 | 0 | 1 | 1 |
Thrombopoietin | 1 | 0 | 0 | 1 |
alpha-galactosidase | 1 | 0 | 0 | 1 |
Spike glycoprotein | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 1 | 1 |
urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
plasminogen precursor | 1 | 0 | 0 | 1 |
urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
Transmembrane protease serine 2 | 0 | 0 | 1 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
Polymerase basic protein 2 | 0 | 0 | 1 | 1 |
RNA-directed RNA polymerase catalytic subunit | 0 | 0 | 1 | 1 |
Polymerase acidic protein | 0 | 0 | 1 | 1 |
Procathepsin L | 0 | 0 | 1 | 1 |
Replicase polyprotein 1a | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
Adenosine receptor A3 | 0 | 1 | 0 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
Adenosylhomocysteinase | 0 | 0 | 0 | 2 |
Adenosine receptor A2a | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
Genome polyprotein | 0 | 0 | 1 | 1 |
Angiotensin-converting enzyme 2 | 0 | 0 | 1 | 1 |
Chain A, Arginase 1 | 0 | 1 | 0 | 1 |
Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
glp-1 receptor, partial | 1 | 0 | 0 | 1 |
streptokinase A precursor | 0 | 0 | 1 | 1 |
twin arginine protein translocation system - TatA protein | 0 | 0 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |