| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 5 | 0 | 0 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| lamin isoform A-delta10 | 7 | 0 | 0 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 5 |
| Bile salt export pump | 0 | 6 | 0 | 6 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Thromboxane-A synthase | 0 | 1 | 0 | 1 |
| Prostaglandin E2 receptor EP3 subtype | 0 | 1 | 0 | 1 |
| Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 1 | 2 |
| Prostaglandin E2 receptor EP1 subtype | 0 | 1 | 0 | 1 |
| Prostacyclin receptor | 0 | 1 | 1 | 2 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 3A1 | 0 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 3 | 0 | 0 | 3 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| tumor necrosis factor | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 5 | 0 | 0 | 5 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 2 | 1 | 4 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 2 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 3 | 0 | 3 |
| Aurora kinase B | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Albumin | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 2 | 0 | 2 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| Snq2p | 0 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 3 | 0 | 0 | 3 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 2 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 3 | 1 | 4 |
| Sphingomyelin phosphodiesterase | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 3 | 1 | 4 |
| Alpha-2C adrenergic receptor | 0 | 3 | 1 | 4 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 3 | 1 | 4 |
| Alpha-1D adrenergic receptor | 0 | 3 | 1 | 4 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Pleiotropic ABC efflux transporter of multiple drugs | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5B | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 3 | 0 | 3 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A3 | 0 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 3 | 1 | 4 |
| Histamine H2 receptor | 1 | 1 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 3 | 0 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 3 | 0 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 3 | 0 | 3 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | 0 | 1 | 0 | 1 |
| Sodium channel protein type 7 subunit alpha | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| Envelope glycoprotein | 0 | 0 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 3 | 0 | 3 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 3 | 0 | 3 |
| Sodium channel protein type 11 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 8 subunit alpha | 0 | 1 | 0 | 1 |
| Transporter | 0 | 2 | 0 | 2 |
| Sodium channel protein type 10 subunit alpha | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | 0 | 1 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| geminin | 4 | 0 | 0 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| Opioid receptor, delta 1b | 0 | 1 | 0 | 1 |
| Opioid receptor homologue | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Acyl-CoA desaturase 1 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Translocator protein | 0 | 0 | 1 | 1 |
| Histidine decarboxylase | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Proteinase-activated receptor 1 | 0 | 1 | 1 | 2 |
| Delta-type opioid receptor | 0 | 1 | 0 | 2 |
| Delta-type opioid receptor | 0 | 2 | 1 | 4 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 6 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 4 |
| Delta-type opioid receptor | 0 | 2 | 1 | 4 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 5 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
| Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1) | 0 | 1 | 0 | 1 |
| Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1) | 0 | 1 | 0 | 1 |
| Chain A, Beta-arrestin 1 | 0 | 0 | 1 | 1 |
| Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR | 0 | 0 | 1 | 1 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Retinol-binding protein 4 | 0 | 0 | 1 | 1 |
| Beta-lactoglobulin | 0 | 0 | 1 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Chain A, Acetylcholinesterase | 0 | 0 | 1 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| Cytochrome P450 2B1 | 0 | 1 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| Trace amine-associated receptor 1 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |