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cialit

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Cialit: Tissue preservative. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	23672771
MeSH ID	M0004471

Synonyms (18)

Synonym
otimerate sodium
ethyl(hydrogen 2-mercapto-5-benzoxazolecarboxylato)mercury, sodium salt
otimeratum natricum
16509-11-8
otimerate sodique
unii-m3a126v69i
otimerato sodico
einecs 240-572-0
cialit
m3a126v69i ,
otimerate sodium [inn]
mercurate(1-), (2,3-dihydro-2-thioxo-5-benzoxazolecarboxylato(2-)-s)ethyl-, sodium
otimerate sodique [french]
otimerato sodico [spanish]
otimeratum natricum [latin]
DTXSID40167843
Q27283433
sodium;(5-carboxylato-1,3-benzoxazol-2-yl)sulfanyl-ethylmercury

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (48)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	41 (85.42)	18.7374
1990's	7 (14.58)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	27.41 (24.57)
Research Supply Index	4.06 (2.92)
Research Growth Index	4.29 (4.65)
Search Engine Demand Index	34.37 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (27.41)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (1.79%)	5.53%
Reviews	2 (3.57%)	6.00%
Case Studies	3 (5.36%)	4.05%
Observational	0 (0.00%)	0.25%
Other	50 (89.29%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	4.56	8	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
1-propanol 1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.. propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.	1.96	1	propan-1-ols; short-chain primary fatty alcohol	metabolite; protic solvent
cetyltrimethylammonium ion Cetrimonium: Cetyltrimethylammonium compound whose salts and derivatives are used primarily as topical antiseptics.. cetyltrimethylammonium ion : A quaternary ammonium ion in which the substituents on nitrogen are one hexadecyl and three methyl groups.	1.98	1	quaternary ammonium ion
glutaral Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.. glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.	3.75	3	dialdehyde	cross-linking reagent; disinfectant; fixative
oxazoles Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.	1.93	1	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
mercury Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.. mercury(0) : Elemental mercury of oxidation state zero.	2.36	2	elemental mercury; zinc group element atom	neurotoxin
propiconazole Orbit: Bony cavity that holds the eyeball and its associated tissues and appendages.	1.95	1	conazole fungicide; cyclic ketal; dichlorobenzene; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic
sodium sulfide sodium sulfide: see also record for sodium bisulfide; actisoufre is the sodium sulfide component of sulfur-containing thermal springs which is also found in Saccharomyces cerevisiae	6.97	1
chlorhexidine Chlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.. chlorhexidine : A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge.	6.98	1	biguanides; monochlorobenzenes	antibacterial agent; antiinfective agent
thimerosal Thimerosal: An ethylmercury-sulfidobenzoate that has been used as a preservative in VACCINES; ANTIVENINS; and OINTMENTS. It was formerly used as a topical antiseptic. It degrades to ethylmercury and thiosalicylate.. thimerosal : An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.	4.17	5	alkylmercury compound	antifungal drug; antiseptic drug; disinfectant; drug allergen

Condition	Relationship Strength	Studies
Hand Injuries General or unspecified injuries to the hand.	1.94	1
ENT Diseases [description not available]	1.96	1
Inguinal Hernia [description not available]	1.95	1
Anus Prolapse [description not available]	1.95	1
Diaphragmatic Hernia, Traumatic [description not available]	1.95	1
Diaphragmatic Eventration A congenital abnormality characterized by the elevation of the DIAPHRAGM dome. It is the result of a thinned diaphragmatic muscle and injured PHRENIC NERVE, allowing the intra-abdominal viscera to push the diaphragm upward against the LUNG.	1.95	1
Hernia, Inguinal An abdominal hernia with an external bulge in the GROIN region. It can be classified by the location of herniation. Indirect inguinal hernias occur through the internal inguinal ring. Direct inguinal hernias occur through defects in the ABDOMINAL WALL (transversalis fascia) in Hesselbach's triangle. The former type is commonly seen in children and young adults; the latter in adults.	1.95	1
Corneal Diseases Diseases of the cornea.	1.98	1
Complication, Intraoperative [description not available]	1.98	1
Corneal Edema An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.	1.98	1
HIV Coinfection [description not available]	1.99	1
HIV Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.	2.38	2
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).	1.99	1
Complication, Postoperative [description not available]	2.64	3
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	2.64	3
Cadaver A dead body, usually a human body.	2.37	2
Ankle Injuries Harm or hurt to the ankle or ankle joint usually inflicted by an external source.	1.95	1
Ear Infection [description not available]	1.95	1
CJD (Creutzfeldt-Jakob Disease) [description not available]	1.97	1
Creutzfeldt-Jakob Syndrome A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))	1.97	1
Infection, Postoperative Wound [description not available]	1.97	1
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.	1.97	1
Acquired Immune Deficiency Syndrome [description not available]	1.97	1
Acquired Immunodeficiency Syndrome An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.	1.97	1

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