Page last updated: 2024-12-08

ribulose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ribulose: 5-carbon keto sugar; minor descriptor (75-85); on-line & Index Medicus search PENTOSES (75-85); RN given refers to (erythro)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID151261
CHEMBL ID195989
CHEBI ID17173
SCHEMBL ID44299
MeSH IDM0262921

Synonyms (38)

Synonym
erythropentulose
d-erythropentulose
z7u4kg0138 ,
unii-z7u4kg0138
einecs 207-687-8
CHEBI:17173 ,
d-erythro-pent-2-ulose
d-rul
5556-48-9
ribulose
d-ribulose ,
488-84-6
3912CBFB-62B6-40A7-ABE6-D010F07A767D
(3r,4r)-1,3,4,5-tetrahydroxypentan-2-one
CHEMBL195989
1,3,4,5-tetrahydroxypentan-2-one
arabinulose
2-ribulose
dl-erythro-pentulose
erythro-2-pentulose
araboketose
unii-djm6k5t6ya
djm6k5t6ya ,
RBL ,
SCHEMBL44299
ZAQJHHRNXZUBTE-NQXXGFSBSA-N
d-ribulose [mi]
ribulose, d-
d-erythro-2-ketopentose
dl-erythro-2-pentulose
ribulose, dl-
ribosone
erythro-pentulose
DTXSID30204115
AKOS027430464
erythro-2-pentulose (9ci)
Q40075
A937275

Research Excerpts

Overview

L-Ribulose is an important chiral lead molecule used for the synthesis of l-ribose, a high-value rare sugar. It can be used as a precursor for the production of other rare sugars of high market value.

ExcerptReferenceRelevance
"L-Ribulose is a rare sugar and the key precursor for L-ribose production."( Recent advances in properties, production, and applications of L-ribulose.
Chen, J; Mu, W; Wu, H; Zhang, W, 2020
)
1.35
"l-Ribulose is an important chiral lead molecule used for the synthesis of, among others, l-ribose, a high-value rare sugar used in the preparation of antiviral drugs. "( Dehydrogenation of ribitol with Gluconobacter oxydans: production and stability of L-ribulose.
De Muynck, C; Pereira, C; Soetaert, W; Vandamme, E, 2006
)
1.28
"L-Ribulose is a rare and expensive sugar that can be used as a precursor for the production of other rare sugars of high market value such as L-ribose. "( Metabolic engineering of Lactobacillus plantarum for production of L-ribulose.
Helanto, M; Kiviharju, K; Leisola, M; Nyyssölä, A, 2007
)
1.3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
human metaboliteAny mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
ribulose
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (5)

PathwayProteinsCompounds
D-Arabinose Degradation I511
ribitol degradation114
D-arabinose degradation II012
D-arabinose degradation I419
superpathway of pentose and pentitol degradation4661
D-arabinose degradation07

Bioassays (1)

Assay IDTitleYearJournalArticle
AID246191Effective concentration to induce a quorum signal in Vibrio harveyi(by binding Lux P protein)2005Bioorganic & medicinal chemistry letters, May-02, Volume: 15, Issue:9
Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (101)

TimeframeStudies, This Drug (%)All Drugs %
pre-199031 (30.69)18.7374
1990's3 (2.97)18.2507
2000's21 (20.79)29.6817
2010's34 (33.66)24.3611
2020's12 (11.88)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 50.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index50.40 (24.57)
Research Supply Index4.62 (2.92)
Research Growth Index5.15 (4.65)
Search Engine Demand Index135.55 (26.88)
Search Engine Supply Index3.48 (0.95)

This Compound (50.40)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews4 (3.96%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other97 (96.04%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]