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L-glutamine derivative
A proteinogenic amino acid derivative resulting from reaction of L-glutamine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of L-glutamine by a heteroatom.
ChEBI ID: 24317
Members (4)
| Member | Definition | Role |
|---|---|---|
| coprine | A non-proteinogenic L-alpha-amino acid that is L-glutamine in which one of the hydrogens attached to the amide nitrogen is replaced by a 1-hydroxycyclopropyl group. Found in the ink-cap mushroom, Coprinus atramentarius, it causes an unpleasant hypersensitivity to alcohol (the 'disulfiram effect'). | coprine |
| glutaurine | A dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals. | glutaurine zwitterion; glutaurine |
| mannopine | A hexitol derivative that is D-mannitol in which the hydroxy group at position 1 is replaced by the alpha-amino group of L-glutamine. It is produced in crown gall tumours induced in a wide range of dicotyledenous plants by Agrobacterium tumefaciens. | mannopine |
| ophthalmic acid | A L-glutamine derivative that is L-glutamine substituted by a 1-[(carboxymethyl)amino]-1-oxobutan-2-yl at the terminal amino nitrogen atom. | ophthalmic acid |
Research
Studies (139)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 69 (49.64) | 18.7374 |
| 1990's | 28 (20.14) | 18.2507 |
| 2000's | 17 (12.23) | 29.6817 |
| 2010's | 23 (16.55) | 24.3611 |
| 2020's | 2 (1.44) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (0.70%) | 5.53% |
| Reviews | 5 (3.52%) | 6.00% |
| Case Studies | 2 (1.41%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 134 (94.37%) | 84.16% |