Compounds > n,n-dimethylcyclohexylamine
Page last updated: 2024-12-05

n,n-dimethylcyclohexylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N,N-dimethylcyclohexylamine: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

N,N-dimethylcyclohexylamine : A tertiary amine consisting of cyclohexane having a dimethylamino substituent. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID7415
CHEMBL ID3186662
CHEBI ID59022
SCHEMBL ID15595
MeSH IDM0115470

Synonyms (57)

Synonym
CHEBI:59022 ,
dimethylcyclohexylamine
cyclohexylamine, n,n-dimethyl-
cyclohexanamine, n,n-dimethyl-
brn 1919922
un2264
nsc 163904
einecs 202-715-5
hsdb 5323
n,n-dimethylaminocyclohexane
dimethylcyclicsiloxane hydrolyzate
n-cyclohexyldimethylamine
wln: l6tj an1 & 1
98-94-2
n,n-dimethyl-n-cyclohexylamine
nsc163904
(dimethylamino)cyclohexane
n,n-dimethylcyclohexanamine
cyclohexylamine,n-dimethyl-
cyclohexanamine,n-dimethyl-
n,n-dimethylcyclohexylamine
cyclohexyldimethylamine
nsc-163904
n,n-dimethylcyclohexylamine, 99%
D0705
dimethylaminocyclohexane
A845928
NCGC00249031-01
tox21_201360
NCGC00258912-01
dtxsid9026633 ,
cas-98-94-2
dtxcid906633
ec 202-715-5
unii-n1h19e7hta
n1h19e7hta ,
dimethylcyclohexylamine [un2264] [corrosive]
FT-0629528
AKOS015850797
cyclohexyl(dimethyl)ammonium
SCHEMBL15595
n,n-dimethylcyclohexylamine [hsdb]
n,n-dimethylcyclohexyl amine
n, n-dimethylcyclohexylamine
n-cyclohexyl-n,n-dimethylamine
n,n-dimethyl-cyclohexylamine
cyclohexyl-dimethylamine
dimethyl cyclohexyl amin
dimethyl cyclohexylamine
W-100060
STR02891
un 2264
CHEMBL3186662
mfcd00003844
F0001-2323
Q25945666
8ia ,
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
tertiary amineA compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency74.12220.003041.611522,387.1992AID1159552; AID1159555
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency67.96230.001530.607315,848.9004AID1224841; AID1224849
estrogen nuclear receptor alphaHomo sapiens (human)Potency53.98440.000229.305416,493.5996AID743079
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency54.43720.001019.414170.9645AID743191
heat shock protein beta-1Homo sapiens (human)Potency61.07960.042027.378961.6448AID743210
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency76.25500.011917.942071.5630AID651632
Ataxin-2Homo sapiens (human)Potency76.25500.011912.222168.7989AID651632
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (18)

Processvia Protein(s)Taxonomy
cell population proliferationATPase family AAA domain-containing protein 5Homo sapiens (human)
positive regulation of B cell proliferationATPase family AAA domain-containing protein 5Homo sapiens (human)
nuclear DNA replicationATPase family AAA domain-containing protein 5Homo sapiens (human)
signal transduction in response to DNA damageATPase family AAA domain-containing protein 5Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorATPase family AAA domain-containing protein 5Homo sapiens (human)
isotype switchingATPase family AAA domain-containing protein 5Homo sapiens (human)
positive regulation of DNA replicationATPase family AAA domain-containing protein 5Homo sapiens (human)
positive regulation of isotype switching to IgG isotypesATPase family AAA domain-containing protein 5Homo sapiens (human)
DNA clamp unloadingATPase family AAA domain-containing protein 5Homo sapiens (human)
regulation of mitotic cell cycle phase transitionATPase family AAA domain-containing protein 5Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorATPase family AAA domain-containing protein 5Homo sapiens (human)
positive regulation of cell cycle G2/M phase transitionATPase family AAA domain-containing protein 5Homo sapiens (human)
negative regulation of receptor internalizationAtaxin-2Homo sapiens (human)
regulation of translationAtaxin-2Homo sapiens (human)
RNA metabolic processAtaxin-2Homo sapiens (human)
P-body assemblyAtaxin-2Homo sapiens (human)
stress granule assemblyAtaxin-2Homo sapiens (human)
RNA transportAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (8)

Processvia Protein(s)Taxonomy
protein bindingATPase family AAA domain-containing protein 5Homo sapiens (human)
ATP bindingATPase family AAA domain-containing protein 5Homo sapiens (human)
ATP hydrolysis activityATPase family AAA domain-containing protein 5Homo sapiens (human)
DNA clamp unloader activityATPase family AAA domain-containing protein 5Homo sapiens (human)
DNA bindingATPase family AAA domain-containing protein 5Homo sapiens (human)
RNA bindingAtaxin-2Homo sapiens (human)
epidermal growth factor receptor bindingAtaxin-2Homo sapiens (human)
protein bindingAtaxin-2Homo sapiens (human)
mRNA bindingAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (10)

Processvia Protein(s)Taxonomy
Elg1 RFC-like complexATPase family AAA domain-containing protein 5Homo sapiens (human)
nucleusATPase family AAA domain-containing protein 5Homo sapiens (human)
cytoplasmAtaxin-2Homo sapiens (human)
Golgi apparatusAtaxin-2Homo sapiens (human)
trans-Golgi networkAtaxin-2Homo sapiens (human)
cytosolAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
membraneAtaxin-2Homo sapiens (human)
perinuclear region of cytoplasmAtaxin-2Homo sapiens (human)
ribonucleoprotein complexAtaxin-2Homo sapiens (human)
cytoplasmic stress granuleAtaxin-2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.14

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index35.14 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index44.85 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (35.14)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
phenethylamine
phenethylamine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7016. 2-phenylethylamine : A phenylethylamine having the phenyl substituent at the 2-position.		2.610alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
spermidine
[no description available]		2.610polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
4-methylmorpholine
[no description available]		1.9810
triethylamine
[no description available]		1.9810tertiary amine
n,n-dimethylethylamine
[no description available]		1.9810
sodium hydroxide
Sodium Hydroxide: A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed)		2.2110alkali metal hydroxide
n,n-dimethylphenylethylamine
N,N-dimethylphenylethylamine: RN given refers to parent cpd		2.0510primary amine
ConditionIndicatedRelationship StrengthStudiesTrials