| Assay ID | Title | Year | Journal | Article |
|---|
| AID477277 | Inhibition of GluA1 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID722025 | Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to -40 mV by two electrode voltage clamp analysis | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors. |
| AID710278 | Antagonist activity at rat glutamate N1/2A receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. |
| AID477279 | Inhibition of GluA4 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID1713545 | Inhibition of tyrosinase in mouse B16-F10 cells at 0.421 uM using L-DOPA as substrate incubated for 30 mins followed by substrate addition and measured after 40 mins | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477271 | Activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as effect of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID710276 | Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. |
| AID1713536 | Mixed type inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-substrate complex constant measured for 15 mins by UV-vis spectrophotometry based Line-weaver Burk plot analysis | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID1713533 | Inhibition of mushroom tyrosinase using L-DOPA as substrate measured for 15 mins by UV-vis spectrophotometry | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477275 | Inhibition of recombinant GluA4 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID477272 | Activity at recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes assessed as effect of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID1713535 | Mixed type inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibitory constant measured for 15 mins by UV-vis spectrophotometry based Line-weaver Burk plot analysis | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID1713541 | Inhibition of melanin production in mouse B16-F10 cells incubated for 48 hrs | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID1713538 | Cytotoxicity against human M4Be cells assessed as reduction in cell viability at 42.1 uM incubated for 6 hrs by MTT assay | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477282 | Selectivity ratio of IC50 for rat recombinant GluA1A2 receptor flop isoform to IC50 for rat recombinant GluA1 receptor flop isoform | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID722024 | Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -80 to -40 mV by two electrode voltage clamp analysis | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors. |
| AID1713534 | Inhibition of mushroom tyrosinase using DHICA as substrate measured for 15 mins by UV-vis spectrophotometry | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID722023 | Selectivity ratio of IC50 for rat GluA1 receptor flip form to IC50 for rat GluN1/2A receptor | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
| Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors. |
| AID689749 | Inhibition of rat GluN1/2A expressed in xenopus laevis oocytes assessed as inhibition of glycine-evoked current at membrane potential of -60 mV by voltage-clamp electrophysiology | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3
| Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. |
| AID477276 | Inhibition of recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID710277 | Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology assay | 2012 | Journal of medicinal chemistry, Nov-26, Volume: 55, Issue:22
| General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. |
| AID477278 | Inhibition of GluA3 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID689750 | Inhibition of rat GluA1 expressed in xenopus laevis oocytes assessed as inhibition of glutamate-evoked current at membrane potential of -60 mV by voltage-clamp electrophysiology | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3
| Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. |
| AID477281 | Inhibition of rat recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID1713548 | Reduction in alpha-MSH-induced tyrosinase expression in mouse B16-F10 cells at 0.041 uM incubated for 48 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477280 | Inhibition of rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID1713549 | Reduction in alpha-MSH-induced TRP-1 expression in mouse B16-F10 cells at 0.041 uM incubated for 48 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477273 | Inhibition of recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| AID1713537 | Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability at 42.1 uM incubated for 6 hrs by MTT assay | 2016 | Bioorganic & medicinal chemistry, 11-15, Volume: 24, Issue:22
| ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. |
| AID477274 | Inhibition of recombinant GluA3 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiological assay | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4
| Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |