Page last updated: 2024-09-03

argiotoxin-636 and philanthotoxin 343

argiotoxin-636 has been researched along with philanthotoxin 343 in 7 studies

Compound Research Comparison

Studies
(argiotoxin-636)
Trials
(argiotoxin-636)
Recent Studies (post-2010)
(argiotoxin-636)
Studies
(philanthotoxin 343)
Trials
(philanthotoxin 343)
Recent Studies (post-2010) (philanthotoxin 343)
53073906

Protein Interaction Comparison

ProteinTaxonomyargiotoxin-636 (IC50)philanthotoxin 343 (IC50)
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)0.0802
Glutamate receptor 1Rattus norvegicus (Norway rat)1.465
Glutamate receptor 2Rattus norvegicus (Norway rat)0.13
Glutamate receptor 3Rattus norvegicus (Norway rat)0.13
Glutamate receptor 4Rattus norvegicus (Norway rat)0.13
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)0.0077
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)0.0077
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)0.0802
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)2.739
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)2.739
Metabotropic glutamate receptor 1Homo sapiens (human)0.023

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
England, PM; Fleming, JJ1
Blagbrough, IS; Brackley, PT; Bruce, M; Bycroft, BW; Mather, AJ; Millington, S; Sudan, HL; Usherwood, PN1
Jones, MG; Lodge, D1
Bell, DR; Brackley, PT; Choi, SK; Nakanishi, K; Usherwood, PN1
Carter, C; Fage, D; Nankai, M1
Green, AC; Nakanishi, K; Usherwood, PN1
Donevan, SD; Rogawski, MA1

Other Studies

7 other study(ies) available for argiotoxin-636 and philanthotoxin 343

ArticleYear
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
    Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4

    Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA

2010
Arthropod toxins as leads for novel insecticides: an assessment of polyamine amides as glutamate antagonists.
    Toxicon : official journal of the International Society on Toxinology, 1992, Volume: 30, Issue:3

    Topics: Animals; Biological Assay; Glutamates; Grasshoppers; Indoleacetic Acids; Insecticides; Muscles; Oocytes; Phenols; Phenylacetates; Polyamines; Receptors, Glutamate; Receptors, Neurotransmitter; Spider Venoms; Structure-Activity Relationship; Wasp Venoms; Xenopus laevis

1992
Comparison of some arthropod toxins and toxin fragments as antagonists of excitatory amino acid-induced excitation of rat spinal neurones.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Arthropod Venoms; Asparagine; Female; Ibotenic Acid; Indoleacetic Acids; Iontophoresis; Microelectrodes; N-Methylaspartate; Neurons; Neurotoxins; Phenols; Phenylacetates; Polyamines; Rats; Rats, Inbred Strains; Spinal Cord; Wasp Venoms

1991
Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3

    Topics: Animals; Arthropod Venoms; Cloning, Molecular; Excitatory Amino Acid Antagonists; Female; Indoleacetic Acids; Kainic Acid; Male; N-Methylaspartate; Oocytes; Phenols; Phenylacetates; Polyamines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA; Spider Venoms; Transcription, Genetic; Xenopus

1993
NMDA receptor subtype selectivity: eliprodil, polyamine spider toxins, dextromethorphan, and desipramine selectively block NMDA-evoked striatal acetylcholine but not spermidine release.
    Journal of neurochemistry, 1995, Volume: 64, Issue:5

    Topics: Acetylcholine; Animals; Corpus Striatum; Desipramine; Dextromethorphan; Indoleacetic Acids; N-Methylaspartate; Phenols; Phenylacetates; Piperidines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spider Venoms

1995
Polyamine amides are neuroprotective in cerebellar granule cell cultures challenged with excitatory amino acids.
    Brain research, 1996, Apr-22, Volume: 717, Issue:1-2

    Topics: Amides; Animals; Arthropod Venoms; Calcium; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Glutamic Acid; Indoleacetic Acids; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenols; Phenylacetates; Polyamines; Potassium; Rats; Rats, Wistar; Spider Venoms

1996
Multiple actions of arylalkylamine arthropod toxins on the N-methyl-D-aspartate receptor.
    Neuroscience, 1996, Volume: 70, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Glycine; Indoleacetic Acids; Membrane Potentials; Patch-Clamp Techniques; Phenols; Phenylacetates; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spider Venoms

1996