Page last updated: 2024-07-11 10:36:19
EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10).
ChEBI ID: 67232
Members (2)
| Member | Definition | Class | Studies | Trials |
|---|---|---|---|---|
| 1-D-1,2-anhydro-myo-inositol | A conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B. | conduritol epoxide | 4 | 0 |
| 3-epi-fagomine | A member of the class of hydroxypiperidines that is piperidine carrying a hydroxymethyl substituent at position 2 as well as two hydroxy substituents at positions 3 and 4 (the 2R,3R,4S-diastereomer). | hydroxypiperidine; | 36 | 0 |
Protein Targets (5)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Ceramide glucosyltransferase | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Rattus norvegicus (Norway rat) | IC50 | 3.1000 | 2 | 2 |
| Lysosomal acid glucosylceramidase | Bos taurus (cattle) | IC50 | 5.6000 | 1 | 1 |
| Beta-galactosidase | Bos taurus (cattle) | IC50 | 2.2500 | 2 | 2 |
Research
Research (10)
| Studies | Pre-1990 | 1990's | 2000's | 2010's | Post-2020 |
|---|---|---|---|---|---|
| 10 | 0 | 4 | 2 | 4 | 0 |