homonojirimycin has been researched along with miglustat in 3 studies
| Studies (homonojirimycin) | Trials (homonojirimycin) | Recent Studies (post-2010) (homonojirimycin) | Studies (miglustat) | Trials (miglustat) | Recent Studies (post-2010) (miglustat) |
|---|---|---|---|---|---|
| 15 | 0 | 7 | 383 | 28 | 185 |
| Protein | Taxonomy | homonojirimycin (IC50) | miglustat (IC50) |
|---|---|---|---|
| Sucrase-isomaltase | Mus musculus (house mouse) | 1.05 | |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | 5.55 | |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | 5 | |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | 0.1 | |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | 0.5 | |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | 2.156 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 5 | |
| Glycogen debranching enzyme | Homo sapiens (human) | 10 | |
| Lysosomal alpha-glucosidase | Mus musculus (house mouse) | 9 | |
| Non-lysosomal glucosylceramidase | Mus musculus (house mouse) | 0.14 | |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | 3.7 | |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | 0.2057 | |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | 0.42 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, I; Asano, N; Compain, P; Godin, G; Ikeda, K; Kato, A; Martin, O; Yu, L | 1 |
| Benjamin, ER; Boyd, RE; Khanna, R; Lee, G; Rybczynski, P; Valenzano, KJ; Wustman, BA | 1 |
| Dhavale, DD; Karanjule, NS; Markad, SD; Sabharwal, SG; Sharma, T | 1 |
1 review(s) available for homonojirimycin and miglustat
| Article | Year |
|---|---|
Pharmacological chaperones as therapeutics for lysosomal storage diseases.
Topics: Cell Line; Glycolipids; Humans; Lysosomal Storage Diseases; Molecular Chaperones; Structure-Activity Relationship | 2013 |
2 other study(ies) available for homonojirimycin and miglustat
| Article | Year |
|---|---|
Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.
Topics: 1-Deoxynojirimycin; Cell Line; Dose-Response Relationship, Drug; Gaucher Disease; Glucosamine; Glucosylceramidase; Humans; Molecular Chaperones; Molecular Mimicry; Structure-Activity Relationship | 2006 |
Synthesis and evaluation of glycosidase inhibitory activity of N-butyl 1-deoxy-D-gluco-homonojirimycin and N-butyl 1-deoxy-L-ido-homonojirimycin.
Topics: 1-Deoxynojirimycin; Amination; Enzyme Inhibitors; Glycoside Hydrolases; Imino Pyranoses; Inhibitory Concentration 50; Models, Chemical; Piperidines | 2006 |