An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-galactosidase (EC 3.2.1.23).
ChEBI ID: 132518
Member | Definition | Class |
---|---|---|
3-epi-fagomine | A member of the class of hydroxypiperidines that is piperidine carrying a hydroxymethyl substituent at position 2 as well as two hydroxy substituents at positions 3 and 4 (the 2R,3R,4S-diastereomer). | 3-epi-fagomine |
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
Beta-galactosidase | Bos taurus (cattle) | IC50 | 2.2500 | 2 | 2 |
Ceramide glucosyltransferase | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
Lactase-phlorizin hydrolase | Rattus norvegicus (Norway rat) | IC50 | 3.1000 | 2 | 2 |
Lysosomal acid glucosylceramidase | Bos taurus (cattle) | IC50 | 5.6000 | 1 | 1 |
Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |