homonojirimycin has been researched along with 1-deoxynojirimycin in 14 studies
| Studies (homonojirimycin) | Trials (homonojirimycin) | Recent Studies (post-2010) (homonojirimycin) | Studies (1-deoxynojirimycin) | Trials (1-deoxynojirimycin) | Recent Studies (post-2010) (1-deoxynojirimycin) |
|---|---|---|---|---|---|
| 15 | 0 | 7 | 1,548 | 141 | 558 |
| Protein | Taxonomy | homonojirimycin (IC50) | 1-deoxynojirimycin (IC50) |
|---|---|---|---|
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | 2.366 | |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | 1 | |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | 1.015 | |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | 2 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | 0.3479 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 1 | |
| Glycogen debranching enzyme | Homo sapiens (human) | 10 | |
| Glycogen debranching enzyme | Oryctolagus cuniculus (rabbit) | 0.19 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-amylase | Geobacillus stearothermophilus | 1.67 | |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | 1.3 | |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | 0.3125 | |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | 0.04 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asano, N; Chen, FJ; Haruno, M; Kato, A; Kimura, I; Nojima, H; Sugihara, Y | 1 |
| Adachi, I; Asano, N; Compain, P; Godin, G; Ikeda, K; Kato, A; Martin, O; Yu, L | 1 |
| Adachi, I; Asano, N; Ikeda, K; Imahori, T; Kamiyama, O; Kato, A; Kuriyama, C; Okamoto, T; Sanae, F; Takahata, H | 1 |
| Benjamin, ER; Boyd, RE; Khanna, R; Lee, G; Rybczynski, P; Valenzano, KJ; Wustman, BA | 1 |
| Asano, N; Elbein, AD; Nash, RJ; Pan, YT; Zeng, Y | 1 |
| Asano, N; Baba, M; Fleet, GW; Itoh, T; Kato, A; Kizu, H; Lilley, PM; Matsui, K; Nash, RJ; Nishida, M; Shimada, Y; Watkin, DJ; Watson, AA | 1 |
| Asano, N; Compain, P; Kizu, H; Martin, OR | 1 |
| Arisawa, M; Asano, N; Fleet, GW; Ikeda, K; Kameda, Y; Kizu, H; Miyauchi, M; Nash, RJ; Nishida, M; Takahashi, M; Watson, AA | 1 |
| Dhavale, DD; Karanjule, NS; Markad, SD; Sabharwal, SG; Sharma, T | 1 |
| Adachi, I; Akimitsu, K; Fleet, GW; Izumori, K; Jenkinson, SF; Kato, A; Lenagh-Snow, GM; Morimoto, K; Nakagawa, S; Newberry, SJ; Wormald, MR; Yoshihara, A | 1 |
| Bing, F; Zhang, B; Zhang, G; Zhang, X | 1 |
| Bing, FH; Li, J; Li, YM; Liao, YF; Tian, LQ; Zhang, GB | 1 |
| Akimitsu, K; Butters, TD; Fleet, GW; Glawar, AF; Izumori, K; Jenkinson, SF; Kato, A; Nakagawa, S; Newberry, SJ; Thompson, AL; Yoshihara, A | 1 |
| Carrero-Carralero, C; Martín-Ortiz, A; Ramos, S; Rodríguez-Sánchez, S; Sanz, ML; Soria, AC | 1 |
1 review(s) available for homonojirimycin and 1-deoxynojirimycin
| Article | Year |
|---|---|
Pharmacological chaperones as therapeutics for lysosomal storage diseases.
Topics: Cell Line; Glycolipids; Humans; Lysosomal Storage Diseases; Molecular Chaperones; Structure-Activity Relationship | 2013 |
13 other study(ies) available for homonojirimycin and 1-deoxynojirimycin
| Article | Year |
|---|---|
Antihyperglycemic effects of N-containing sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castanospermum australe in streptozotocin-diabetic mice.
Topics: Animals; Blood Glucose; Carbohydrates; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fabaceae; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Mice; Mice, Inbred Strains; Pancreas; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Time Factors | 1998 |
Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.
Topics: 1-Deoxynojirimycin; Cell Line; Dose-Response Relationship, Drug; Gaucher Disease; Glucosamine; Glucosylceramidase; Humans; Molecular Chaperones; Molecular Mimicry; Structure-Activity Relationship | 2006 |
In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.
Topics: Animals; Caco-2 Cells; Carbohydrate Conformation; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Gaucher Disease; Glycogen; Glycoside Hydrolases; Hepatocytes; Humans; Imino Sugars; Lysosomes; Rats; Structure-Activity Relationship | 2008 |
Homonojirimycin and N-methyl-homonojirimycin inhibit N-linked oligosaccharide processing.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucosamine; Glycoproteins; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Oligosaccharides; Orthomyxoviridae; Piperidines; Protein Processing, Post-Translational; Viral Envelope Proteins | 1997 |
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Topics: 1-Deoxynojirimycin; Animals; Anti-HIV Agents; Cattle; Cell Line, Transformed; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; HIV-1; Humans; Imino Pyranoses; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Piperidines; Rats; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication | 1998 |
Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin.
Topics: 1-Deoxynojirimycin; Aza Compounds; Carbohydrate Conformation; Carbohydrates; Enzyme Inhibitors; Glycoside Hydrolases; Imino Pyranoses; Magnetic Resonance Spectroscopy; Molecular Structure; Piperidines; Plant Extracts; Structure-Activity Relationship | 1999 |
Homonojirimycin analogues and their glucosides from Lobelia sessilifolia and Adenophora spp. (Campanulaceae).
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Asteraceae; Cattle; Glucosides; Glycoside Hydrolases; Imino Pyranoses; Inhibitory Concentration 50; Intestines; Kidney; Liver; Magnetic Resonance Spectroscopy; Male; Piperidines; Plant Extracts; Plant Proteins; Rats; Rats, Wistar | 2000 |
Synthesis and evaluation of glycosidase inhibitory activity of N-butyl 1-deoxy-D-gluco-homonojirimycin and N-butyl 1-deoxy-L-ido-homonojirimycin.
Topics: 1-Deoxynojirimycin; Amination; Enzyme Inhibitors; Glycoside Hydrolases; Imino Pyranoses; Inhibitory Concentration 50; Models, Chemical; Piperidines | 2006 |
Eight stereoisomers of homonojirimycin from D-mannose.
Topics: 1-Deoxynojirimycin; Euphorbiaceae; Mannose; Molecular Structure; Stereoisomerism | 2012 |
Homonojirimycin, an alkaloid from dayflower inhibits the growth of influenza A virus in vitro.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Commelina; Dogs; Harmine; Imino Furanoses; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Mannitol | 2013 |
Protective effect of homonojirimycin from Commelina communis (dayflower) on influenza virus infection in mice.
Topics: 1-Deoxynojirimycin; Animals; Commelina; Cytokines; Dogs; Female; Influenza A virus; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Phytotherapy; Plant Extracts | 2013 |
An approach to 8 stereoisomers of homonojirimycin from (D)-glucose via kinetic & thermodynamic azido-γ-lactones.
Topics: 1-Deoxynojirimycin; Azides; Glucose; Kinetics; Lactones; Models, Molecular; Molecular Conformation; Stereoisomerism; Thermodynamics | 2013 |
Pressurized liquid extraction of Aglaonema sp. iminosugars: Chemical composition, bioactivity, cell viability and thermal stability.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Araceae; Caco-2 Cells; Carbohydrates; Cell Survival; Chemical Phenomena; Gas Chromatography-Mass Spectrometry; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Mannitol; Molecular Weight; Plant Extracts; Pressure | 2016 |