Page last updated: 2024-11-13
fluazaindolizine
Description
fluazaindolizine: a nematicide; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
fluazaindolizine : A member of the class of imidazopyridines that is the amide formed from the formal condensation of the carboxy group of 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid with the sulfonamide nitrogen of 2-chloro-5-methoxybenzene-1-sulfonamide. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 46944253 |
| CHEBI ID | 87543 |
| SCHEMBL ID | 2681429 |
| SCHEMBL ID | 23901458 |
Synonyms (20)
| Synonym |
|---|
| 8-chloro-n-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxamide |
| 8-chloro-n-[(2-chloro-5-methoxyphenyl)-sulfonyl]-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxamide |
| SCHEMBL2681429 |
| 1254304-22-7 |
| CHEBI:87543 |
| 8-chloro-n-(2-chloro-5-methoxybenzene-1-sulfonyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide |
| fluazaindolizine |
| DTXSID30894878 |
| Q27159715 |
| salibro |
| fluazaindolizine [iso] |
| WHQ8UEW6ZK , |
| imidazo(1,2-a)pyridine-2-carboxamide, 8-chloro-n-((2-chloro-5-methoxyphenyl)sulfonyl)-6-(trifluoromethyl)- |
| 8-chloro-n-((2-chloro-5-methoxyphenyl)sulfonyl)-6-(trifluoromethyl)imidazo(1,2-a)pyridine-2-carboxamide |
| ((8-chloro-n-(2-chloro-5-methoxyphenyl)sulfonyl)-6-trifluoromethyl)imidazo(1,2-a)pyridine-2-carboxamide |
| unii-whq8uew6zk |
| 8-chloro-n-(2-chloro-5-methoxyphenyl)sulfonyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide |
| imidazo[1,2-a]pyridine-2-carboxamide, 8-chloro-n-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)-; 8-chloro-n-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide; fluazaindolizine; [[8-chloro-n-(2-chloro-5 |
| SCHEMBL23901458 |
| imidazo[1,2-a]pyridine-2-carboxamide, 8-chloro-n-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)- |
Research Excerpts
Overview
Fluazaindolizine is a new compound for the control of plant-parasitic nematodes (PPNs) with an unknown and novel mode-of-action.
| Excerpt | Reference | Relevance |
|---|
| "Fluazaindolizine is a new compound for the control of plant-parasitic nematodes (PPNs) with an unknown and novel mode-of-action. " | ( Sublethal fluazaindolizine doses inhibit development of the cyst nematode Heterodera schachtii during sedentary parasitism.
Grundler, FM; Matera, C; Schleker, ASS, 2021) | 2.47 |
| "Fluazaindolizine is a novel sulfonamide nematicide that is currently under commercialization in various countries. " | ( The impact of fluazaindolizine on free-living nematodes and the nematode community structure in a root-knot nematode infested vegetable production system.
Sánchez-Moreno, S; Talavera, M; Thoden, TC; Vela-Delgado, MD; Verdejo-Lucas, S, 2021) | 2.42 |
| "Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. " | ( The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes.
Cordova, D; Daly, A; Desaeger, J; Kucharczyk, R; Lahm, GP; Lett, RM; Meloro, T; Pahutski, TF; Rivera, MA; Smith, BK; Smith, BT; Thoden, T; Wiles, JA, 2017) | 2.24 |
Treatment
Roles (2)
| Role | Description |
|---|
| nematicide | A substance used to destroy pests of the phylum Nematoda (roundworms). |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (7)
| Class | Description |
|---|
| monocarboxylic acid amide | A carboxamide derived from a monocarboxylic acid. |
| aromatic amide | An amide in which the amide linkage is bonded directly to an aromatic system. |
| monomethoxybenzene | Compounds containing a benzene skeleton substituted with one methoxy group. |
| monochlorobenzenes | Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. |
| organofluorine pesticide | |
| imidazopyridine | |
| N-sulfonylcarboxamide | A mixed diacylamine resulting from the formal condensation of the nitrogen of a carboxamide with a sulphonic acid. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 40.46
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 40.46 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.71 (4.65) | | Search Engine Demand Index | 50.58 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |