Page last updated: 2024-12-05
fensulfothion
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
fensulfothion: was MH 1972-92 (see under INSECTICIDES, ORGANOTHIOPHOSPHATE 1972-90); use ORGANOTHIOPHOSPHORUS COMPOUNDS to search FENSULFOTHION 1972-92 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 8292 |
| CHEMBL ID | 3186021 |
| CHEBI ID | 34760 |
| SCHEMBL ID | 73185 |
| MeSH ID | M0198147 |
Synonyms (78)
| Synonym |
|---|
| BIDD:ER0310 |
| o,o-diaethyl-o-(4-methylsulfinyl-phenyl)-thionophosphat [german] |
| ent 24,945 |
| vuagt 96 |
| terracur p |
| epa pesticide chemical code 032701 |
| s 767 |
| vuagt 108 |
| ai3-24945 |
| diethyl p-methylsulfinylphenyl thiophosphate |
| o,o-diethyl o-(4-(methylsulfinyl)phenyl) phosphorothioate |
| oms 37 |
| einecs 204-114-3 |
| daconit |
| bayer 25141 |
| hsdb 1580 |
| phenol, p-(methylsulfinyl)-, o-ester with o,o-diethyl phosphorothioate |
| chemagro 25141 |
| caswell no. 343 |
| bay 25141 |
| p,o-diethyl o-p-(methylsulfinyl)phenyl thiophosphate |
| fensulfothion [bsi:iso] |
| phosphorothioic acid, o,o-diethyl o-(p-(methylsulfinyl)phenyl) ester |
| brn 2219515 |
| o,o-diaethyl-o-4-methylsulfinyl-phenyl-monothiophosphat [german] |
| fensulfothion |
| phosphorothioic acid, o,o-diethyl o-[4-(methylsulfinyl)phenyl] ester |
| 115-90-2 |
| fensulfothion, analytical standard |
| CHEBI:34760 , |
| dasanit |
| phosphorothioic acid, o,o-diethyl o-(4-(methylsulfinyl)phenyl) ester |
| o,o-diethyl o-(p-(methylsulfinyl)phenyl) phosphorothioate |
| o,o-diethyl o-[4-(methylsulfinyl)phenyl] thiophosphate |
| o,o-diethyl o-p-(methylsulfinyl)phenyl thiophosphate |
| o,o-diethyl o-[4-(methanesulfinyl)phenyl] phosphorothioate |
| o,o-diethyl o-4-methylsulphinylphenyl phosphorothioate |
| NCGC00163892-01 |
| diethoxy-(4-methylsulfinylphenoxy)-sulfanylidenephosphorane |
| xdnbjtqlkcijbv-uhfffaoysa- |
| inchi=1/c11h17o4ps2/c1-4-13-16(17,14-5-2)15-10-6-8-11(9-7-10)18(3)12/h6-9h,4-5h2,1-3h3 |
| A26234 |
| o,o-diethyl o-4-(methylsulfinyl)phenyl phosphorothioate |
| fensulfothione |
| NCGC00255240-01 |
| dtxcid601953 |
| tox21_301858 |
| cas-115-90-2 |
| dtxsid6021953 , |
| unii-vb39b105po |
| vb39b105po , |
| o,o-diaethyl-o-(4-methylsulfinyl-phenyl)-thionophosphat |
| o,o-diaethyl-o-4-methylsulfinyl-phenyl-monothiophosphat |
| AKOS015890636 |
| SCHEMBL73185 |
| phosphorothioic acid o,o-diethyl o-(4-(methylsulfinyl)phenyl) ester |
| bay-25141 |
| sulfonium, (4-((diethoxyphosphinothioyl)oxy)phenyl)hydroxymethyl-, inner salt |
| fensulfothion [hsdb] |
| 1-(diethoxythioxophosphinooxy)-4-(methylsulfinyl)benzene |
| o,o-diethyl o-4-methylsulfinylphenyl phosphorothioate |
| fensulfothion [mi] |
| fensulfothion [iso] |
| b 25141 |
| o,o-diethyl o-[p-(methylsulfinyl)phenyl] phosphorothioate |
| o,o-diethyl o-[4-(methylsulfinyl)phenyl] phosphorothioate |
| o,o-diethyl o-[4-(methylsulfinyl)phenyl] thiophosphate # |
| phosphorothioic acid, o,o-diethyl o-[p-(methylsulfinyl)phenyl] ester |
| bayer s767 |
| o o-diethyl o-[4-(methylsulphinyl)phenyl phosphorothioate |
| CHEMBL3186021 |
| J-003331 |
| J-521362 |
| fensulfothion, pestanal(r), analytical standard |
| fensulfothion 100 microg/ml in acetonitrile |
| Q5443592 |
| diethoxy-(4-methylsulfinylphenoxy)-sulfanylidene-lambda5-phosphane |
| fensulfothion 1000 microg/ml in toluene |
Research Excerpts
Compound-Compound Interactions
| Excerpt | Reference | Relevance |
|---|---|---|
| "Continuous flow microextraction (CFME) combined with high-performance liquid chromatography-ultraviolet (HPLC-UV) detection has been applied to the analysis of five widely used pesticides, simazine, fensulfothion, etridiazole, mepronil and bensulide, present at trace levels in water samples." | ( Continuous flow microextraction combined with high-performance liquid chromatography for the analysis of pesticides in natural waters. He, Y; Lee, HK, 2006) | 0.52 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Roles (4)
| Role | Description |
|---|---|
| EC 3.1.1.7 (acetylcholinesterase) inhibitor | An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| avicide | A substance used to destroy bird pests (class Aves). |
| nematicide | A substance used to destroy pests of the phylum Nematoda (roundworms). |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Drug Classes (3)
| Class | Description |
|---|---|
| organic thiophosphate | |
| sulfoxide | An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H). |
| organothiophosphate insecticide | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Protein Targets (5)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 70.9799 | 0.0025 | 41.7960 | 15,848.9004 | AID1347395; AID1347398 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 9.8415 | 0.0010 | 22.6508 | 76.6163 | AID1224838; AID1224893 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 41.6196 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982; AID720659 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 61.6448 | 0.0002 | 29.3054 | 16,493.5996 | AID743078 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 14.0498 | 0.0007 | 23.0674 | 1,258.9301 | AID743085; AID743122 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 31.14
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (31.14) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (14.29%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (85.71%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||