Compounds > fensulfothion
Page last updated: 2024-11-05

fensulfothion

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fensulfothion: was MH 1972-92 (see under INSECTICIDES, ORGANOTHIOPHOSPHATE 1972-90); use ORGANOTHIOPHOSPHORUS COMPOUNDS to search FENSULFOTHION 1972-92 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8292
CHEMBL ID3186021
CHEBI ID34760
SCHEMBL ID73185
MeSH IDM0198147

Synonyms (78)

Synonym
BIDD:ER0310
o,o-diaethyl-o-(4-methylsulfinyl-phenyl)-thionophosphat [german]
ent 24,945
vuagt 96
terracur p
epa pesticide chemical code 032701
s 767
vuagt 108
ai3-24945
diethyl p-methylsulfinylphenyl thiophosphate
o,o-diethyl o-(4-(methylsulfinyl)phenyl) phosphorothioate
oms 37
einecs 204-114-3
daconit
bayer 25141
hsdb 1580
phenol, p-(methylsulfinyl)-, o-ester with o,o-diethyl phosphorothioate
chemagro 25141
caswell no. 343
bay 25141
p,o-diethyl o-p-(methylsulfinyl)phenyl thiophosphate
fensulfothion [bsi:iso]
phosphorothioic acid, o,o-diethyl o-(p-(methylsulfinyl)phenyl) ester
brn 2219515
o,o-diaethyl-o-4-methylsulfinyl-phenyl-monothiophosphat [german]
fensulfothion
phosphorothioic acid, o,o-diethyl o-[4-(methylsulfinyl)phenyl] ester
115-90-2
fensulfothion, analytical standard
CHEBI:34760 ,
dasanit
phosphorothioic acid, o,o-diethyl o-(4-(methylsulfinyl)phenyl) ester
o,o-diethyl o-(p-(methylsulfinyl)phenyl) phosphorothioate
o,o-diethyl o-[4-(methylsulfinyl)phenyl] thiophosphate
o,o-diethyl o-p-(methylsulfinyl)phenyl thiophosphate
o,o-diethyl o-[4-(methanesulfinyl)phenyl] phosphorothioate
o,o-diethyl o-4-methylsulphinylphenyl phosphorothioate
NCGC00163892-01
diethoxy-(4-methylsulfinylphenoxy)-sulfanylidenephosphorane
xdnbjtqlkcijbv-uhfffaoysa-
inchi=1/c11h17o4ps2/c1-4-13-16(17,14-5-2)15-10-6-8-11(9-7-10)18(3)12/h6-9h,4-5h2,1-3h3
A26234
o,o-diethyl o-4-(methylsulfinyl)phenyl phosphorothioate
fensulfothione
NCGC00255240-01
dtxcid601953
tox21_301858
cas-115-90-2
dtxsid6021953 ,
unii-vb39b105po
vb39b105po ,
o,o-diaethyl-o-(4-methylsulfinyl-phenyl)-thionophosphat
o,o-diaethyl-o-4-methylsulfinyl-phenyl-monothiophosphat
AKOS015890636
SCHEMBL73185
phosphorothioic acid o,o-diethyl o-(4-(methylsulfinyl)phenyl) ester
bay-25141
sulfonium, (4-((diethoxyphosphinothioyl)oxy)phenyl)hydroxymethyl-, inner salt
fensulfothion [hsdb]
1-(diethoxythioxophosphinooxy)-4-(methylsulfinyl)benzene
o,o-diethyl o-4-methylsulfinylphenyl phosphorothioate
fensulfothion [mi]
fensulfothion [iso]
b 25141
o,o-diethyl o-[p-(methylsulfinyl)phenyl] phosphorothioate
o,o-diethyl o-[4-(methylsulfinyl)phenyl] phosphorothioate
o,o-diethyl o-[4-(methylsulfinyl)phenyl] thiophosphate #
phosphorothioic acid, o,o-diethyl o-[p-(methylsulfinyl)phenyl] ester
bayer s767
o o-diethyl o-[4-(methylsulphinyl)phenyl phosphorothioate
CHEMBL3186021
J-003331
J-521362
fensulfothion, pestanal(r), analytical standard
fensulfothion 100 microg/ml in acetonitrile
Q5443592
diethoxy-(4-methylsulfinylphenoxy)-sulfanylidene-lambda5-phosphane
fensulfothion 1000 microg/ml in toluene

Research Excerpts

Compound-Compound Interactions

ExcerptReferenceRelevance
"Continuous flow microextraction (CFME) combined with high-performance liquid chromatography-ultraviolet (HPLC-UV) detection has been applied to the analysis of five widely used pesticides, simazine, fensulfothion, etridiazole, mepronil and bensulide, present at trace levels in water samples."( Continuous flow microextraction combined with high-performance liquid chromatography for the analysis of pesticides in natural waters.
He, Y; Lee, HK, 2006)		0.52
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (4)

RoleDescription
EC 3.1.1.7 (acetylcholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
avicideA substance used to destroy bird pests (class Aves).
nematicideA substance used to destroy pests of the phylum Nematoda (roundworms).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
organic thiophosphate
sulfoxideAn organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).
organothiophosphate insecticide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
acetylcholinesteraseHomo sapiens (human)Potency70.97990.002541.796015,848.9004AID1347395; AID1347398
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency9.84150.001022.650876.6163AID1224838; AID1224893
pregnane X nuclear receptorHomo sapiens (human)Potency41.61960.005428.02631,258.9301AID1346982; AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency61.64480.000229.305416,493.5996AID743078
aryl hydrocarbon receptorHomo sapiens (human)Potency14.04980.000723.06741,258.9301AID743085; AID743122
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.14

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.14 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.86 (4.65)
Search Engine Demand Index36.71 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.14)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (14.29%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbofuran
Carbofuran: A cholinesterase inhibitor that is used as a systemic insecticide, an acaricide, and nematocide. (From Merck Index, 11th ed)		6.99101-benzofurans;
carbamate ester		acaricide;
agrochemical;
avicide;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nematicide
fenthion
Fenthion: Potent cholinesterase inhibitor used as an insecticide and acaricide.. fenthion : An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.		7.0710organic thiophosphateacaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
safrole
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).. safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.		2.0710benzodioxolesflavouring agent;
insecticide;
metabolite;
plant metabolite
simazine
Simazine: A triazine herbicide.. simazine : A diamino-1,3,5-triazine that is N,N'-diethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.		2.0310chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
sulfoxide
sulfoxide: synergistic insecticide for use with pyrethrum, allethrin, rotenone, ryania, etc.; RN given refers to parent cpd; structure. sulfoxide : An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).		7.0710benzodioxoles
paraoxon
[no description available]		2.0710aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
bensulide
[no description available]		2.0310benzenes
etridiazol
etridiazol: structure. etridiazole : A member of the class of thiadiazoles that is 1,2,4-thiadiazole which is substituted at positions 3 and 5 by trichloromethyl and ethoxy groups, respectively. A fungicide, it has been used particularly for the control of Phytophthora and Pythium species in soils.		2.0310aromatic ether;
organochlorine compound;
thiadiazole antifungal agent;
thiadiazoles		antifungal agrochemical;
nitrification inhibitor
hydroxyl radical
Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.		7.0810oxygen hydride;
oxygen radical;
reactive oxygen species
ConditionIndicatedRelationship StrengthStudiesTrials
Avian Diseases
[description not available]		01.9910
Poisoning
Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.		06.9910