Page last updated: 2024-12-06

sulprofos

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID37125
CHEMBL ID3184587
CHEBI ID38949
SCHEMBL ID73642
MeSH IDM0058046

Synonyms (54)

Synonym
hsdb 6735
o-ethyl o-(4-methylthiophenyl) s-propyl dithiophosphate
ai3-29149
phosphorodithioic acid, o-ethyl o-(4-(methylthio)phenyl) s-propyl ester
einecs 252-545-0
bolstar
sulprofos [bsi:iso]
o-ethyl o-(4-(methylthio)phenyl) s-propyl phosphorodithioate
epa pesticide chemical code 111501
helothion
brn 1990231
o-ethyl o-(4-(methylmercapto)phenyl)-s-n-propylphosphorothionothiolate
bayer ntn 9306
caswell no. 453aa
ntn 9306
bay-ntn-9306
sulprofos, analytical standard
sulprofos
mercaprophos
merpafos
o-ethyl o-[4-(methylsulfanyl)phenyl] s-propyl dithiophosphate
CHEBI:38949 ,
35400-43-2
mercaprofos
o-ethyl o-[4-(methylsulfanyl)phenyl] s-propyl phosphorodithioate
sulprophos
o-ethyl o-(4-(methylthio)phenyl)phosphorodithioic acid s-propyl ester
AC-12073
C19016
cas-35400-43-2
dtxcid6012675
NCGC00255182-01
tox21_301358
dtxsid8032675 ,
AKOS015960699
fux2i5f01b ,
unii-fux2i5f01b
bay ntn 9306
sulprofos [iso]
sulprofos [mi]
sulprofos [hsdb]
(rs)-(o-ethyl o-4-(methylthio)phenyl s-propyl phosphorodithioate)
SCHEMBL73642
JXHJNEJVUNHLKO-UHFFFAOYSA-N
o-ethyl o-[4-(methylsulfanyl)phenyl] s-propyl dithiophosphate #
phosphorodithioic acid, o-ethyl o-[4-(methylthio)phenyl] s-propyl ester
bay-ntn 9306
CHEMBL3184587
sulprofos, pestanal(r), analytical standard
sulprofos 100 microg/ml in cyclohexane
o-ethyl o-4-(methylthio)phenyl s-propyl phosphorodithioate
Q20965240
ethoxy-(4-methylsulfanylphenoxy)-propylsulfanyl-sulfanylidene-lambda5-phosphane
sulprofos 100 microg/ml in toluene
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
EC 3.1.1.7 (acetylcholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
organic thiophosphate
organothiophosphate insecticide
organosulfur compoundAn organosulfur compound is a compound containing at least one carbon-sulfur bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (11)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
GLI family zinc finger 3Homo sapiens (human)Potency50.99340.000714.592883.7951AID1259369; AID1259392
AR proteinHomo sapiens (human)Potency24.33650.000221.22318,912.5098AID1259243
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency10.10320.001022.650876.6163AID1224838; AID1224839; AID1224893
progesterone receptorHomo sapiens (human)Potency68.58960.000417.946075.1148AID1346795
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency2.18720.000214.376460.0339AID720691
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency60.71020.003041.611522,387.1992AID1159552; AID1159553; AID1159555
retinoid X nuclear receptor alphaHomo sapiens (human)Potency38.89520.000817.505159.3239AID1159527; AID1159531
pregnane X nuclear receptorHomo sapiens (human)Potency17.22890.005428.02631,258.9301AID1346982
aryl hydrocarbon receptorHomo sapiens (human)Potency10.27220.000723.06741,258.9301AID743085; AID743122
thyroid stimulating hormone receptorHomo sapiens (human)Potency20.51050.001628.015177.1139AID1224843; AID1224895
heat shock protein beta-1Homo sapiens (human)Potency54.94100.042027.378961.6448AID743210; AID743228
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.42

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.42 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.42)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]