Pyridafenthion is an organophosphorus insecticide that acts as an acetylcholinesterase inhibitor. It is used to control a wide range of insect pests, particularly in agriculture. Pyridafenthion is synthesized through a multi-step process involving reactions with phosphorus-containing compounds. It is known for its effectiveness against various pests, including aphids, whiteflies, and mites. Research into pyridafenthion focuses on its efficacy, potential environmental impacts, and its metabolism and degradation in the environment. The study of pyridafenthion is crucial for understanding its effects on both target pests and non-target organisms, including beneficial insects and humans. Its importance lies in its ability to protect crops from damage by pests while ensuring minimal environmental harm.'
| ID Source | ID |
|---|---|
| PubMed CID | 8381 |
| CHEBI ID | 38881 |
| SCHEMBL ID | 82258 |
| MeSH ID | M0055908 |
| Synonym |
|---|
| brn 0302741 |
| ent 23,968 |
| o,o-diethyl o-(1,6-dihydro-6-oxo-1-phenylpyridazin-3-yl) thiophosphate |
| einecs 204-298-5 |
| 3(2h)-pyridazinone, 6-hydroxy-2-phenyl-, o-ester with o,o-diethyl phosphorothioate |
| o,o-diethyl o-(2,3-dihydro-3-oxo-2-phenyl-6-pyridazinyl)phosphorothioate |
| ai3-23968 |
| o,o-diethylphosphorothioate, o-ester with 6-hydroxy-2-phenyl-3(2h)-pyridazinone |
| pyridafenthion |
| ofnack |
| american cyanamid 12,503 |
| ofnak |
| cl 12503 |
| o-(1,6-dihydro-6-oxo-1-phenylpyridazin-3-yl) o,o-diethyl phosphorothioate |
| phosphorothioic acid, o-(1,6-dihydro-6-oxo-1-phenyl-3-pyridazinyl) o,o-diethyl ester |
| phosphorothioic acid, o,o-diethyl ester, o-ester with 6-hydroxy-2-phenyl-3(2h)pyridazinone |
| CHEBI:38881 |
| pyridaphenthion |
| o,o-diethyl o-(6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl) thiophosphate |
| o,o-diethyl o-(6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl) phosphorothioate |
| 119-12-0 |
| 6-diethoxyphosphinothioyloxy-2-phenylpyridazin-3-one |
| 98m0vdd56z , |
| 4-25-00-00030 (beilstein handbook reference) |
| unii-98m0vdd56z |
| C18762 |
| AKOS016014212 |
| FT-0603320 |
| pyridaphenthion [jan] |
| o-(1,6)-dihydro-6-oxo-1-phenylpyridazin-3-yl) o,o-diethyl phosphorothioate |
| o,o-diethyl o-(2,3-dihydro-3-oxo-2-phenyl-6-pyridazinyl) phosphorothioate |
| pyridiphenthion |
| o,o-diethyl phosphorothioate o-ester with 6-hydroxy-2-phenyl-3(2h)-pyridazinone |
| phosphorothioic acid, o,o-diethyl ester, o-ester with 6-hydroxy-2-phenyl-3(2h)-pyridazinone |
| oreste |
| SCHEMBL82258 |
| o,o-diethyl o-(6-oxo-1-phenyl-1,6-dihydro-3-pyridazinyl) thiophosphate # |
| CXJSOEPQXUCJSA-UHFFFAOYSA-N |
| DTXSID2042355 |
| pyridaphenthion, pestanal(r), analytical standard |
| pyridaphenthion 100 microg/ml in cyclohexane |
| tetrabromo-o-sulfobenzoicanhydride |
| phosphorothioic acid,o-(1,6-dihydro-6-oxo-1-phenyl-3-pyridazinyl) o,o-diethyl ester |
| o,o-diethyl o-6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl phosphorothioate |
| Q1741694 |
| phosphorothioic acid, o-(1,6-dihydro-6-oxo-1-phenyl-3-pyridazinyl)o,o-diethyl ester |
| pyridaphenthion 1000 microg/ml in acetone |
| Role | Description |
|---|---|
| EC 3.1.1.7 (acetylcholinesterase) inhibitor | An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| organic thiophosphate | |
| organothiophosphate insecticide | |
| pyridazinone | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.39) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||