| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| geminin | 6 | 0 | 0 | 6 |
| Gamma-aminobutyric acid receptor subunit rho-1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 1 | 0 | 1 |
| Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 4 | 0 | 1 | 0 | 1 |
| Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
| Solute carrier family 15 member 2 | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 3 | 0 | 0 | 3 |
| GLI family zinc finger 3 | 8 | 0 | 0 | 8 |
| AR protein | 8 | 0 | 0 | 8 |
| nuclear receptor subfamily 1, group I, member 3 | 7 | 0 | 0 | 7 |
| glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| pregnane X nuclear receptor | 6 | 0 | 0 | 6 |
| cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 6 | 0 | 6 |
| Muscarinic acetylcholine receptor M2 | 0 | 7 | 2 | 13 |
| Muscarinic acetylcholine receptor M4 | 0 | 7 | 1 | 10 |
| Muscarinic acetylcholine receptor M1 | 0 | 5 | 1 | 8 |
| Muscarinic acetylcholine receptor M3 | 0 | 4 | 1 | 7 |
| Muscarinic acetylcholine receptor M4 | 0 | 3 | 1 | 6 |
| Muscarinic acetylcholine receptor M5 | 0 | 3 | 1 | 6 |
| Muscarinic acetylcholine receptor M5 | 0 | 6 | 1 | 9 |
| Muscarinic acetylcholine receptor M2 | 0 | 5 | 2 | 10 |
| Muscarinic acetylcholine receptor M1 | 0 | 7 | 1 | 12 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 7 | 1 | 10 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 2 | 3 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | 6 | 0 | 0 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
| thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 9 | 0 | 0 | 9 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 1 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 2 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 4 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 2 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 2 | 0 | 0 | 2 |
| Cytochrome P450 2C8 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2B6 | 0 | 3 | 0 | 3 |
| Liver carboxylesterase 1 | 0 | 0 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 5 | 0 | 5 |
| Rap guanine nucleotide exchange factor 4 | 2 | 0 | 0 | 2 |
| P2Y purinoceptor 12 | 0 | 1 | 0 | 1 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 3 | 0 | 0 | 3 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| Luciferase | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 4 | 0 | 0 | 4 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 3 | 0 | 0 | 3 |
| TDP1 protein | 5 | 0 | 0 | 5 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 isoform 1 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| Ornithine decarboxylase | 0 | 0 | 0 | 1 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Retinoic acid receptor alpha | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 4 | 0 | 4 |
| Retinoic acid receptor gamma | 0 | 1 | 0 | 1 |
| Retinoic acid receptor beta | 0 | 1 | 0 | 1 |
| Cellular retinoic acid-binding protein 2 | 0 | 0 | 1 | 1 |
| Mitogen-activated protein kinase 1 | 0 | 1 | 0 | 1 |
| Retinoic acid receptor RXR-alpha | 0 | 1 | 0 | 1 |
| Retinoic acid receptor RXR-beta | 0 | 1 | 0 | 1 |
| Retinoic acid receptor RXR-gamma | 0 | 1 | 0 | 1 |
| Cellular retinoic acid-binding protein 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 4 | 0 | 4 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Cellular retinoic acid-binding protein 1 | 0 | 0 | 1 | 1 |
| Mitogen-activated protein kinase 14 | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 1 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 6 | 0 | 0 | 6 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GALC protein | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| G | 3 | 0 | 0 | 3 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 0 | 0 | 3 |
| Interferon beta | 4 | 0 | 0 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
| Cytochrome P450 1A1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 1A2 | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 3 | 0 | 3 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 3 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 0 | 0 | 3 |
| Cytochrome P450 1B1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 3 | 0 | 0 | 3 |
| Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 0 | 0 | 3 |
| cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, A alpha chain | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| Gastrin/cholecystokinin type B receptor | 0 | 1 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| MBT domain-containing protein 1 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 4 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 3 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 4 | 0 | 4 |
| Lethal(3)malignant brain tumor-like protein 1 | 0 | 1 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| chaperonin-containing TCP-1 beta subunit homolog | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 0 | 0 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | 0 | 0 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | 0 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Albumin | 0 | 1 | 0 | 1 |
| Polymerase acidic protein | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Stromelysin-1 | 0 | 0 | 1 | 1 |
| Tyrosine-protein phosphatase YopH | 0 | 1 | 0 | 1 |
| High mobility group protein B1 | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | 0 | 1 | 0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | 0 | 1 | 0 | 3 |
| Estrogen receptor | 0 | 0 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Cystathionine gamma-lyase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | 0 | 0 | 0 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | 0 | 0 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 8 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Ubiquitin-like domain-containing CTD phosphatase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | 0 | 0 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | 0 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| procathepsin L isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |