phenylephrine-hydrochloride and Hidrocystoma

Eccrine and apocrine hidrocystomas are uncommon, benign, cystic proliferations of the sweat glands usually located on the head and neck area.. To describe the key clinical and histopathological characteristics of a large series of hidrocystomas in Greece to improve diagnostic accuracy, and to perform a historical review of the medical term hidrocystoma.. A case series of 22 hidrocystomas from 20 consecutive patients treated with surgery at University Hospital of Heraklion in Crete, Greece, from January 1, 1998 to January 1, 2020 was performed along with a comprehensive historical literature review of the term hidrocystoma and its corresponding term hydatis from ancient Greek literature to the present. Data were obtained from medical records. All patients had a histopathologically confirmed diagnosis of hidrocystoma. Formalin-fixed paraffin-embedded (FFPE) sections of 22 tumors of the 20 consecutive patients were retrieved from the pathology laboratory archive and stained for SMA, p63, and GCDFP-15 with immunochemistry and periodic acid-Schiff (PAS) histochemical stain.. Overall, 22 hidrocystomas (11 apocrine and 11 eccrine hidrocystomas) surgically excised from 20 patients were included in this study. Of the 20 patients, 10 (50%) were male and 10 (50%) were female, with a mean age of 56 ± 15 years. Hidrocystomas commonly occurred on the eyelids (73%), inner canthus (9%), eyebrow (4.5%), neck (4.5%), nose (4.5%), and ear (4.5%). All apocrine hidrocystomas stained positive for SMA, GCDFP-15, CAM 5.2, PAS, and PAS-D. No recurrence was observed.. Here we have presented the clinicopathological characteristics of the largest case series of hidrocystomas in Europe and the Mediterranean region. Only apocrine hidrocystomas stained positive for SMA, GCDFP-15, CAM 5.2, PAS, and PAS-D.

Topics: Adult; Aged; Europe; Eyelids; Female; Hidrocystoma; Humans; Male; Middle Aged; Nose; Sweat Gland Neoplasms

Hidrocystomas are benign tumors of apocrine or eccrine epithelium. They most commonly occur on the head and neck, especially periorbitally. Albeit rare, these adnexal tumors may present as pigmented lesions.. To describe a patient with a pigmented eccrine hidrocystoma of his nose and to review the features of other individuals with pigmented hidrocystoma of the nasal epithelium.. PubMed was used to search the follow terms: hidrocystoma and pigmented. All papers were reviewed and relevant manuscripts, along with their reference citations were evaluated.. A 52-year-old man who presented with a pigmented eccrine hidrocystoma on his nasal bridge was described. The features of three previously described patients with pigmented hidrocystoma of the nose were evaluated. The tumors presented as single or multiple, less than 2mm, blue papules. Our patient's tumor would intermittently bleed, which prompted consideration of a possible basal cell carcinoma. Biopsy established the diagnosis showing a cystic lesion lined by eccrine epithelium with pigmented secretion within the cyst's lumen. The cyst content stained positive with Fontana-Masson stain. Our patient's excisional biopsy resulted in excellent cosmetic appearance and complete removal of the benign adnexal tumor.. Pigmented hidrocystomas may be mistaken for other skin lesions, such as a pigmented basal cell carcinoma and melanoma. A biopsy readily establishes the diagnosis. We respectfully suggest that a hidrocystoma located on the nose that is pigmented be referred to as a PHONE: pigmented hidrocystoma of the nasal epithelium.

Topics: Hidrocystoma; Humans; Hyperpigmentation; Male; Middle Aged; Nose; Skin; Sweat Gland Neoplasms

Topics: Child; Eccrine Glands; Hidrocystoma; Humans; Male; Nose; Skin Abnormalities; Sweat Gland Neoplasms

Topics: Child, Preschool; Diagnosis, Differential; Follow-Up Studies; Hidrocystoma; Humans; Male; Nose; Sweat Gland Neoplasms

Topics: Biopsy; Dermoscopy; Female; Hidrocystoma; Humans; Hyperpigmentation; Middle Aged; Nose; Skin; Sweat Gland Neoplasms

Topics: Aged; Aged, 80 and over; Carcinoma, Basal Cell; Diagnosis, Differential; Female; Hidrocystoma; Humans; Melanoma; Nevus, Blue; Nose; Skin Neoplasms