| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| TDP1 protein | 3 | 0 | 0 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | 4 | 0 | 0 | 4 |
| core protein, partial | 0 | 1 | 0 | 1 |
| geminin | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 6 | 0 | 0 | 6 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 4 | 0 | 6 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 4 | 0 | 6 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Inositol monophosphatase 1 | 2 | 0 | 0 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| AR protein | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| glucocerebrosidase | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 2 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Thymidylate synthase | 0 | 2 | 0 | 2 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 1 | 0 | 2 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Multidrug resistance associated protein | 0 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | 0 | 0 | 1 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| Hsf1 protein | 0 | 0 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 2 | 0 | 2 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 2 | 2 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 2 | 1 | 4 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | 0 | 0 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit rho-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 2 | 1 | 4 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent taurine transporter | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 2 | 1 | 3 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 2 | 1 | 3 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 2 | 2 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 2 | 2 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 2 | 0 | 2 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 2 | 1 | 3 |
| Sterol O-acyltransferase 1 | 0 | 0 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 0 | 1 | 1 |
| Histone deacetylase 7 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 2 | 1 | 4 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 2 | 0 | 2 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 2 | 1 | 4 |
| Platelet glycoprotein VI | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 2 | 0 | 2 |
| Histone deacetylase 5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 1 | 0 | 1 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D26 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5B | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 1 | 0 | 3 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D4 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Chain X, Thyroid hormone receptor beta-1 | 0 | 0 | 1 | 1 |
| Chain X, Thyroid hormone receptor beta-1 | 0 | 0 | 1 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 1 | 0 | 2 |
| Solute carrier organic anion transporter family member 1A5 | 0 | 0 | 0 | 1 |
| Prothrombin | 0 | 0 | 1 | 1 |
| Transthyretin | 0 | 0 | 0 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Thyroid hormone receptor alpha | 0 | 2 | 2 | 4 |
| Thyroid hormone receptor beta | 0 | 2 | 2 | 4 |
| Proliferating cell nuclear antigen | 0 | 1 | 0 | 1 |
| Thyroid hormone receptor beta | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 2 | 0 | 2 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 2 | 2 |
| Solute carrier organic anion transporter family member 1A2 | 0 | 0 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 4A1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1C1 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |