| Assay ID | Title | Year | Journal | Article |
|---|
| AID1244344 | Antifungal activity against Sporothrix schenckii incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1190623 | Terminal half life in rabbit administered intravaginally after 1 hr | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4
| Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies. |
| AID977604 | Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID1190616 | Spermicidal activity against human sperm by microscopic analysis | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4
| Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies. |
| AID386921 | Antifungal activity against Candida albicans after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID301285 | Antifungal activity against Candida albicans MTCC 183 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID1244338 | Inhibition of HIV1 reverse transcriptase at 100 ug/ml incubated for 1 hr by ELISA method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1054552 | Spermicidal activity in human semen assessed as sperm immobilization at 0.1 % w/v up to 30 seconds by phase contrast microscopy | 2013 | European journal of medicinal chemistry, , Volume: 70 | Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. |
| AID301292 | Antifungal activity against Candida albicans ATCC 66027 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID301290 | Antifungal activity against Candida albicans ATCC 10453 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID550087 | Antifungal activity against Candida parapsilosis after 48 hrs by broth microdilution assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID550088 | Antifungal activity against Candida albicans MTCC-183 after 48 hrs by broth microdilution assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID677472 | Cytotoxicity against human HeLa cells by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents. |
| AID685501 | HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells | 2012 | Proceedings of the National Academy of Sciences of the United States of America, May-29, Volume: 109, Issue:22
| Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. |
| AID550089 | Antifungal activity against Candida albicans isolate CDRI after 48 hrs by broth microdilution assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID263884 | Spermicidal activity against human spermatozoa | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9
| The spermicidal and antitrichomonas activities of SSRI antidepressants. |
| AID467903 | Antifungal activity against Candida albicans after 48 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2
| Imidazole derivatives as possible microbicides with dual protection. |
| AID467909 | Cytotoxicity against human HeLa cells at 200 ug/ml after 24 hrs by MTT assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2
| Imidazole derivatives as possible microbicides with dual protection. |
| AID1054550 | Cytotoxicity against human HeLa cells after 24 hrs by LDH assay | 2013 | European journal of medicinal chemistry, , Volume: 70 | Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. |
| AID677473 | Antimicrobial activity against Lactobacillus jensenii | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID263885 | Antitrichomonas activity against Trichomonas vaginalis after 48 hrs | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9
| The spermicidal and antitrichomonas activities of SSRI antidepressants. |
| AID1244343 | Antifungal activity against Cryptococcus neoformans incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID977601 | Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID550086 | Antifungal activity against Candida albicans after 48 hrs by broth microdilution assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID386926 | Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID550083 | Cytotoxicity against human HeLa cells at 200 ug/ml after 24 hrs by MTT based colorimetric assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID664684 | Toxicity against Lactobacillus jensenii ATCC 25258 | 2012 | ACS medicinal chemistry letters, Feb-09, Volume: 3, Issue:2
| Potentiating Metronidazole Scaffold against Resistant Trichomonas: Design, Synthesis, Biology and 3D-QSAR Analysis. |
| AID301286 | Antifungal activity against Candida albicans MTCC 1346 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID386920 | Spermicidal activity in liquefied human semen assessed as drug level required to kill 100% sperm in 20 seconds | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID677410 | Spermicidal activity against human spermatozoa at 10 mg/ml by modified sander-cramer assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents. |
| AID301287 | Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID1190615 | Antimicrobial activity against Trichomonas vaginalis after 3 to 48 hrs by trypan blue exclusion assay | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4
| Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies. |
| AID685503 | HARVARD: Inhibition of blood stage Plasmodium falciparum Dd2 infection | 2012 | Proceedings of the National Academy of Sciences of the United States of America, May-29, Volume: 109, Issue:22
| Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. |
| AID1244357 | Terminal half life in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1244347 | Antifungal activity against Candida parapsilosis ATCC 22019 incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1244339 | Spermicidal activity in liquefied human semen assessed as reduction in motile spermatozoa incubated at 37 degC for 30 mins | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1054549 | Growth inhibition of Lactobacillus acidophilus after 72 hrs by colony counting method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. |
| AID301289 | Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID386924 | Antifungal activity against Trichophyton mentagrophytes after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID433251 | Spermicidal activity in rat spermatozoa assessed as sperm mobilization | 2009 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 19, Issue:16
| Efficient synthesis of 3,3-diheteroaromatic oxindole analogues and their in vitro evaluation for spermicidal potential. |
| AID664683 | Cytotoxicity against human HeLa cells | 2012 | ACS medicinal chemistry letters, Feb-09, Volume: 3, Issue:2
| Potentiating Metronidazole Scaffold against Resistant Trichomonas: Design, Synthesis, Biology and 3D-QSAR Analysis. |
| AID1244346 | Antifungal activity against Aspergillus fumigatus incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID550085 | Antitrichomonas activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID301284 | Antifungal activity against Candida albicans after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID301291 | Antifungal activity against Candida albicans ATCC 60193 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID301288 | Antifungal activity against Candida krusei ATCC 6258 after 48 hrs by broth micro dilution technique | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID1054551 | Trichomonacidal activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay | 2013 | European journal of medicinal chemistry, , Volume: 70 | Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. |
| AID1244354 | Tmax in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID386922 | Antifungal activity against Cryptococcus neoformans after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID1244351 | Stability in simulated vaginal fluid at pH 4.2 at 200 ug/ml by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID467908 | Antifungal activity against Candida parapsilosis after 48 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2
| Imidazole derivatives as possible microbicides with dual protection. |
| AID467900 | Sperimcidal activity against human spermatozoa assessed as sperm motility at 1 % drug solution% | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2
| Imidazole derivatives as possible microbicides with dual protection. |
| AID977600 | pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID1244355 | Apparent oral volume of distribution in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID386925 | Antifungal activity against Aspergillus fumigatus after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID301282 | Spermicidal activity against human spermatozoa | 2007 | Bioorganic & medicinal chemistry, Nov-01, Volume: 15, Issue:21
| Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents. |
| AID677471 | Antimicrobial activity against Trichomonas vaginalis ATCC 25258 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents. |
| AID386923 | Antifungal activity against Sporothrix schenckii after 48 hrs by broth microdilution technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID1244341 | Anti-trichomonas activity against MTZ-resistant Trichomonas vaginalis incubated for 3 to 48 hrs by trypan blue exclusion assay | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID550084 | Spermicidal activity against human spermatozoa assessed as immobilization measured for 60 seconds by visual scoring | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID1244340 | Anti-trichomonas activity against MTZ-susceptible Trichomonas vaginalis incubated for 3 to 48 hrs by trypan blue exclusion assay | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID550090 | Antifungal activity against Candida albicans NCIM-3557 after 48 hrs by broth microdilution assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID1244345 | Antifungal activity against Trichophyton mentagrophytes incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1244358 | Drug level in plasma of New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1244352 | Cmax in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID1054553 | Spermicidal activity in human semen assessed as sperm immobilization at 1.0 % w/v up to 30 seconds by phase contrast microscopy | 2013 | European journal of medicinal chemistry, , Volume: 70 | Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. |
| AID1244342 | Antifungal activity against Candida albicans incubated for 48 hrs by broth micro-dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID1190622 | Cmax in rabbit administered administered intravaginally after 1 hr | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4
| Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies. |
| AID1244356 | Apparent oral clearance in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID571948 | Toxicity against human cervical tissue explants after 2 hrs by MTT assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2
| Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. |
| AID685500 | HARVARD: Cytotoxicity in HepG2 cell line | 2012 | Proceedings of the National Academy of Sciences of the United States of America, May-29, Volume: 109, Issue:22
| Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. |
| AID467902 | Antitrichomonal activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2
| Imidazole derivatives as possible microbicides with dual protection. |
| AID1244353 | AUC (0 to infinity) in New-Zealand rabbit at 33 mg/kg dosed through vaginal administration by LC-MS/MS method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. |
| AID386927 | Antitrichomonas activity against Trichomonas vaginalis after 48 hrs by trypan blue staining | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10
| Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. |
| AID664682 | Spermicidal activity against human spermatozoa assessed as immobilization measured for 60 seconds | 2012 | ACS medicinal chemistry letters, Feb-09, Volume: 3, Issue:2
| Potentiating Metronidazole Scaffold against Resistant Trichomonas: Design, Synthesis, Biology and 3D-QSAR Analysis. |
| AID1183876 | Cytotoxicity against human HeLa cells | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Design and synthesis of γ-butyrolactone derivatives as potential spermicidal agents. |
| AID571949 | Toxicity against human cervical tissue explants after 24 hrs by MTT assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2
| Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. |
| AID677470 | Antimicrobial activity against clinical isolate of Trichomonas vaginalis | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents. |
| AID977603 | pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID550082 | Toxicity against Lactobacillus acidophilus at 200 ug/ml after 24 hrs by microplate reader | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. |
| AID1183875 | Spermicidal activity in human semen assessed as induction of spermatozoa immotility at <0.1% w/v by Sander-Cramer method | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Design and synthesis of γ-butyrolactone derivatives as potential spermicidal agents. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
| Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |