Page last updated: 2024-12-07
ro 43-5054
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
Ro 43-5054: structure given in first source; low molecular weight, noncyclic, peptidomimetic inhibitor [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 132121 |
| CHEMBL ID | 138429 |
| SCHEMBL ID | 7299599 |
| MeSH ID | M0209628 |
Synonyms (17)
| Synonym |
|---|
| 138107-58-1 |
| n-(n-(n-(p-amidinobenzoyl)-beta-alanyl)-l-alpha-aspartyl)-3-phenyl-l-alanine |
| l-phenylalanine, n-(n-(n-(4-(aminoiminomethyl)benzoyl)-beta-alanyl)-l-alpha-aspartyl)- |
| ro 43-5054 |
| p-amidinobenzoyl-beta-alanyl-aspartyl-phenylalanine |
| ro 435054 |
| CHEMBL138429 |
| SCHEMBL7299599 |
| DTXSID50160466 |
| n-(4-carbamimidoylbenzoyl)-beta-alanyl-l-alpha-aspartyl-l-phenylalanine |
| 5yb , |
| ro-435054 |
| (s)-3-(3-(4-carbamimidoylbenzamido)propanamido)-4-(((s)-1-carboxy-2-phenylethyl)amino)-4-oxobutanoic acid |
| Q27456123 |
| (3s)-3-[3-[(4-carbamimidoylbenzoyl)amino]propanoylamino]-4-[[(1s)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid |
| PD161581 |
| AKOS040747408 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID73164 | Inhibition of fibrinogen binding to immobilized fibrinogen receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23 | Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID223375 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by adenosine 5'-diphosphate-(ADP) | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23 | Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID217303 | Inhibition of fibrinogen binding to immobilized vitronectin receptor | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23 | Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID223376 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by collagen | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23 | Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| AID223377 | Inhibition of platelet aggregation in human-platelet rich plasma(h-PRP) induced by thrombin | 1992 | Journal of medicinal chemistry, Nov-13, Volume: 35, Issue:23 | Low molecular weight, non-peptide fibrinogen receptor antagonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (8)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 11.87
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.87) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||