arginyl-glycyl-aspartyl-phenylalanine and arginyl-glycyl-aspartyl-valine

arginyl-glycyl-aspartyl-phenylalanine has been researched along with arginyl-glycyl-aspartyl-valine* in 1 studies

Other Studies

1 other study(ies) available for arginyl-glycyl-aspartyl-phenylalanine and arginyl-glycyl-aspartyl-valine

ArticleYear
[Studies on the synthesis and activities of RGD related peptides].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:4

    In the binding of Fgn to GP IIb/IIIa, RGD is the key sequence. In the present paper, RGDS, RGDV and RGDF were synthesized by use of solution method. Bioassay indicated that the C-terminal amino acid residues were very important for their antithrombosis effects. Conformational studies showed that their antithrombosis potency may depend on their total energies. The observation of their vasodilation effects suggests that this kind of function is worthy to be further studied.

    Topics: Animals; Fibrinolytic Agents; Male; Oligopeptides; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Vasodilation

1997