| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Glycogen Phosphorylase B | 0 | 0 | 1 | 1 |
| Chain B, Glycogen Phosphorylase B | 0 | 0 | 1 | 1 |
| Chain A, ADP-dependent glucokinase | 0 | 1 | 0 | 1 |
| Chain A, Ribonuclease pancreatic | 0 | 1 | 0 | 1 |
| Chain A, Ribonuclease pancreatic | 0 | 1 | 0 | 1 |
| Chain A, phosphodiesterase-nucleotide pyrophosphatase | 0 | 1 | 0 | 1 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | 0 | 0 | 1 | 1 |
| Chain B, GLYCOGEN PHOSPHORYLASE B | 0 | 0 | 1 | 1 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | 0 | 0 | 1 | 1 |
| RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
| AR protein | 5 | 0 | 0 | 5 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 0 | 1 | 0 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | 0 | 0 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | 0 | 0 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 2 | 0 | 1 | 0 | 1 |
| Alcohol dehydrogenase E chain | 0 | 1 | 0 | 1 |
| Alcohol dehydrogenase S chain | 0 | 1 | 0 | 1 |
| L-lactate dehydrogenase A chain | 0 | 1 | 1 | 2 |
| Adenylate kinase isoenzyme 1 | 0 | 0 | 0 | 1 |
| Fructose-1,6-bisphosphatase 1 | 0 | 1 | 0 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | 0 | 0 | 0 | 1 |
| Fructose-1,6-bisphosphatase 1 | 0 | 1 | 0 | 1 |
| 2-dehydropantoate 2-reductase | 0 | 1 | 1 | 2 |
| Inosine-5'-monophosphate dehydrogenase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| 5'-nucleotidase | 0 | 0 | 0 | 1 |
| Choline O-acetyltransferase | 0 | 1 | 0 | 1 |
| Adenylate kinase 2, mitochondrial | 0 | 1 | 0 | 2 |
| GTP:AMP phosphotransferase AK3, mitochondrial | 0 | 0 | 0 | 1 |
| Adenosine receptor A1 | 0 | 0 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | 0 | 1 | 0 | 2 |
| P2Y purinoceptor 2 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 1 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 1 | 0 | 0 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | 0 | 0 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | 0 | 0 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | 0 | 0 | 0 | 1 |
| Glycine--tRNA ligase | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | 0 | 0 | 2 | 2 |
| Adenosine deaminase-like protein | 0 | 0 | 0 | 1 |
| Protease | 0 | 4 | 3 | 9 |
| P2Y purinoceptor 11 | 0 | 0 | 1 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | 0 | 0 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | 0 | 0 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | 0 | 0 | 2 | 2 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 0 | 0 | 1 |
| Alanine racemase, biosynthetic | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| PPM1D protein | 2 | 0 | 0 | 2 |
| TDP1 protein | 5 | 0 | 0 | 5 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 0 | 1 | 4 | 5 |
| Replicase polyprotein 1ab | 0 | 1 | 4 | 5 |
| glucose-6-phosphate 1-dehydrogenase isoform b | 0 | 1 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Transmembrane protease serine 2 | 0 | 1 | 4 | 5 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| DNA ligase | 0 | 1 | 0 | 1 |
| Interferon beta | 4 | 0 | 0 | 4 |
| Riboflavin-binding protein | 0 | 0 | 1 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Histidine-rich protein PFHRP-II | 0 | 1 | 0 | 2 |
| Procathepsin L | 0 | 1 | 4 | 5 |
| Muscarinic acetylcholine receptor M2 | 0 | 3 | 0 | 3 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 4 | 0 | 5 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Replicase polyprotein 1a | 0 | 1 | 4 | 5 |
| Replicase polyprotein 1ab | 0 | 1 | 4 | 5 |
| Replicase polyprotein 1ab | 0 | 3 | 4 | 7 |
| Spike glycoprotein | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 7 | 4 | 11 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| DNA ligase 1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Beta-secretase 1 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 1 | 4 | 7 |
| Calcium-dependent protein kinase 1 | 0 | 0 | 1 | 1 |
| MO15-related protein kinase Pfmrk | 0 | 1 | 0 | 1 |
| DNA ligase A | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 4 | 0 | 4 |
| Sigma intracellular receptor 2 | 0 | 2 | 0 | 2 |
| Phosphoethanolamine N-methyltransferase | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Angiotensin-converting enzyme 2 | 0 | 1 | 4 | 5 |
| Cysteine proteinase falcipain 2a | 0 | 1 | 0 | 1 |
| Cysteine proteinase falcipain 2a | 0 | 1 | 0 | 1 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 2 | 0 | 0 | 2 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| geminin | 4 | 0 | 0 | 4 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| neuropeptide S receptor isoform A | 2 | 0 | 0 | 2 |
| Luciferase | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 4 | 0 | 0 | 4 |
| Genome polyprotein | 0 | 1 | 0 | 1 |
| EWS/FLI fusion protein | 4 | 0 | 0 | 4 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Cyclic GMP-AMP synthase | 0 | 1 | 0 | 1 |
| Toll-like receptor 9 | 0 | 1 | 0 | 1 |
| Toll-like receptor 7 | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | 0 | 1 | 0 | 1 |
| Chain A, protease | 0 | 1 | 0 | 1 |
| Chain B, protease | 0 | 1 | 0 | 1 |
| Chain A, protease | 0 | 0 | 1 | 1 |
| Chain B, protease | 0 | 0 | 1 | 1 |
| Chain A, protease | 0 | 0 | 1 | 1 |
| Chain B, protease | 0 | 0 | 1 | 1 |
| Chain A, protease | 0 | 0 | 1 | 1 |
| Chain B, protease | 0 | 0 | 1 | 1 |
| Chain A, protease | 0 | 0 | 1 | 1 |
| Chain B, protease | 0 | 0 | 1 | 1 |
| Chain A, protease | 0 | 0 | 1 | 1 |
| Chain B, protease | 0 | 0 | 1 | 1 |
| Chain A, Protease | 0 | 1 | 0 | 1 |
| Chain B, Protease | 0 | 1 | 0 | 1 |
| Chain A, Protease | 0 | 1 | 0 | 1 |
| Chain B, Protease | 0 | 1 | 0 | 1 |
| Chain A, Protease | 0 | 1 | 0 | 1 |
| Chain B, Protease | 0 | 1 | 0 | 1 |
| Chain A, PROTEASE RETROPEPSIN | 0 | 1 | 0 | 1 |
| Chain B, PROTEASE RETROPEPSIN | 0 | 1 | 0 | 1 |
| Chain A, Protease Retropepsin | 0 | 1 | 0 | 1 |
| Chain B, Protease Retropepsin | 0 | 1 | 0 | 1 |
| Chain A, Protease Retropepsin | 0 | 1 | 0 | 1 |
| Chain B, Protease Retropepsin | 0 | 1 | 0 | 1 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 3 | 0 | 0 | 3 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 3 | 0 | 0 | 3 |
| Smad3 | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| polyprotein | 3 | 0 | 0 | 3 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Albumin | 0 | 0 | 0 | 4 |
| Gag-Pol polyprotein | 0 | 2 | 0 | 2 |
| Gag-Pol polyprotein | 0 | 2 | 0 | 2 |
| Gag-Pol polyprotein | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Gag-Pol polyprotein | 0 | 2 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Gag-Pol polyprotein | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| CAAX prenyl protease 1 homolog | 0 | 1 | 0 | 1 |
| Plasmepsin V | 0 | 2 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 2 | 0 | 2 |
| Protease | 0 | 4 | 3 | 7 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| GALC protein | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 2 | 0 | 0 | 2 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Chain A, HIV-1 PROTEASE | 0 | 1 | 0 | 1 |
| Chain B, HIV-1 PROTEASE | 0 | 1 | 0 | 1 |
| Chain A, POL polyprotein | 0 | 1 | 0 | 1 |
| Chain B, POL polyprotein | 0 | 1 | 0 | 1 |
| Chain A, POL polyprotein | 0 | 1 | 0 | 1 |
| Chain B, POL polyprotein | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| Chain A, Endothiapepsin | 0 | 1 | 0 | 1 |
| Chain A, Endothiapepsin | 0 | 1 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 2 | 0 | 2 |
| Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A5 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 1 |
| Thromboxane-A synthase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| Vasopressin V1a receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| Thromboxane-A synthase | 0 | 0 | 0 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 2 |
| NS5 | 0 | 1 | 0 | 1 |
| Envelope phospholipase F13 | 0 | 1 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| Glycoprotein hormones alpha chain | 1 | 0 | 0 | 1 |
| Hemagglutinin | 0 | 0 | 1 | 1 |
| Nuclear factor NF-kappa-B p105 subunit | 0 | 1 | 0 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | 0 | 1 | 0 | 1 |
| Transcription factor p65 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |