Buthiobate, also known as S-[[(dibutylthio)carbonyl]methyl] O,O-diethyl phosphorodithioate, is a broad-spectrum acaricide used to control mites on various crops. It acts as an inhibitor of mitochondrial respiration, specifically inhibiting the enzyme succinate dehydrogenase, which is involved in the electron transport chain. Buthiobate is effective against a wide range of mite species, including spider mites, red spider mites, and two-spotted spider mites. Due to its broad-spectrum activity, it is widely used in agriculture to control mite infestations. However, buthiobate is also toxic to other organisms, including fish and bees, and its use has been restricted in some countries due to environmental concerns.'
buthiobate: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 39978 |
| CHEBI ID | 82072 |
| SCHEMBL ID | 21252 |
| SCHEMBL ID | 21253 |
| MeSH ID | M0066284 |
| Synonym |
|---|
| 3-pyridinylcarbonimidodithioic acid butyl (4-(1,1-dimethylethyl)phenyl)methyl ester |
| denmert |
| butyl 4-tert-butylbenzyl n-(3-pyridyl)dithiocarbonimidate |
| s-(n-butyl)-s'-(p-tert-butylbenzyl) n-(3-pyridyl)-5-dithiocarbonimidate |
| carbonimidodithioic acid, 3-pyridinyl-, butyl (4-(1,1-dimethylethyl)phenyl)methyl ester |
| n-(3-pyridyl) s-butyl s'-(p-tert-butylbenzyl)imidodithiocarbonate |
| s-1358 , |
| brn 0496463 |
| butyl p-tert-butylbenzyl 3-pyridylimidodithiocarbonate |
| butiobate |
| butyl (4-(1,1-dimethylethyl)phenyl)methyl 3-pyridinylcarbonimidodithioate |
| buthiobate |
| einecs 257-128-7 |
| buthiobate [bsi:iso] |
| s-n-butyl s'-p-tert-butylbenzyl n-3-pyridyldithiocarbonimidate |
| s 1358 |
| 1-[(4-tert-butylphenyl)methylsulfanyl]-1-butylsulfanyl-n-pyridin-3-ylmethanimine |
| C18930 |
| 51308-54-4 |
| 1279zly2il , |
| unii-1279zly2il |
| buthiobate [mi] |
| buthiobate [iso] |
| SCHEMBL21252 |
| SCHEMBL21253 |
| CHEBI:82072 |
| ZZVVDIVWGXTDRQ-UHFFFAOYSA-N |
| s-n-butyl s'-p-t-butylbenzyl n-3-pyridyldithiocarbonimidate |
| DTXSID70866190 |
| butyl (4-tert-butylphenyl)methyl pyridin-3-ylcarbonodithioimidate |
| Q27155726 |
| butyl (4-(tert-butyl)benzyl) (e)-pyridin-3-ylcarbonimidodithioate |
| Pathway | Proteins | Compounds |
|---|---|---|
| superpathway of ergosterol biosynthesis I | 21 | 56 |
| zymosterol biosynthesis | 8 | 26 |
| superpathway of ergosterol biosynthesis | 22 | 56 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||