| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 3 | 0 | 0 | 3 |
| Chain A, Phospholipase A2 isoform 3 | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 3 | 0 | 0 | 3 |
| GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
| ras protein, partial | 0 | 0 | 1 | 1 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 5 | 0 | 0 | 5 |
| GLS protein | 4 | 0 | 0 | 4 |
| AR protein | 10 | 0 | 0 | 10 |
| aldehyde dehydrogenase 1 family, member A1 | 6 | 0 | 0 | 6 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 5 | 0 | 0 | 5 |
| EWS/FLI fusion protein | 5 | 0 | 0 | 5 |
| glucocorticoid receptor [Homo sapiens] | 7 | 0 | 0 | 7 |
| retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
| estrogen-related nuclear receptor alpha | 8 | 0 | 0 | 8 |
| estrogen nuclear receptor alpha | 10 | 0 | 0 | 10 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| glucocerebrosidase | 3 | 0 | 0 | 3 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| Rac1 protein | 0 | 0 | 1 | 1 |
| IDH1 | 3 | 0 | 0 | 3 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 6 | 0 | 0 | 6 |
| Bloom syndrome protein isoform 1 | 4 | 0 | 0 | 4 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| muscarinic acetylcholine receptor M1 | 3 | 0 | 0 | 3 |
| lethal factor (plasmid) | 2 | 0 | 0 | 2 |
| Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 7 | 0 | 7 |
| Multidrug resistance-associated protein 4 | 0 | 7 | 0 | 7 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 8 | 0 | 8 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 2 | 0 | 3 | 0 | 3 |
| Fatty acid-binding protein, liver | 0 | 2 | 0 | 2 |
| Integrin beta-3 | 0 | 1 | 0 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 0 | 1 | 0 | 1 |
| Glutathione hydrolase 1 proenzyme | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 3 | 0 | 3 |
| Urotensin-2 receptor | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 4 | 0 | 0 | 4 |
| Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 7 | 0 | 7 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 1 | 3 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 7 | 0 | 0 | 7 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| GALC protein | 2 | 0 | 0 | 2 |
| TDP1 protein | 8 | 0 | 0 | 8 |
| GLI family zinc finger 3 | 8 | 0 | 0 | 8 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 5 | 0 | 0 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
| caspase-3 | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| FAD-linked sulfhydryl oxidase ALR | 0 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
| plasminogen precursor | 2 | 0 | 0 | 2 |
| urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
| geminin | 5 | 0 | 0 | 5 |
| peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 7 | 0 | 0 | 7 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 4 | 1 | 1 | 6 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 4 | 0 | 0 | 4 |
| Ataxin-2 | 5 | 0 | 0 | 5 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
| ATP-dependent phosphofructokinase | 3 | 0 | 0 | 3 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| Type IV secretion-like conjugative transfer relaxase protein TraI | 0 | 1 | 0 | 1 |
| 72 kDa type IV collagenase | 0 | 1 | 0 | 1 |
| Stromelysin-1 | 0 | 1 | 0 | 1 |
| Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
| Macrophage metalloelastase | 0 | 1 | 0 | 1 |
| Cereblon isoform 4 | 0 | 3 | 0 | 3 |
| Bromodomain-containing protein 4 | 0 | 1 | 0 | 1 |
| Tyrosine-protein kinase ABL1 | 0 | 0 | 0 | 1 |
| Breakpoint cluster region protein | 0 | 0 | 0 | 1 |
| DNA-binding protein Ikaros | 0 | 0 | 1 | 4 |
| DNA damage-binding protein 1 | 0 | 2 | 1 | 3 |
| Protein cereblon | 0 | 4 | 2 | 9 |
| Zinc finger protein Aiolos | 0 | 0 | 1 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| progesterone receptor | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| G | 2 | 0 | 0 | 2 |
| polyprotein | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Glucocorticoid receptor | 0 | 6 | 2 | 13 |
| Glycine receptor subunit alpha-1 | 0 | 6 | 0 | 6 |
| Androgen receptor | 0 | 3 | 0 | 3 |
| Glycine receptor subunit beta | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-2 | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-3 | 0 | 6 | 0 | 6 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| Snq2p | 0 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Transmembrane protease serine 2 | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Procathepsin L | 0 | 1 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Replicase polyprotein 1a | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Calmodulin-1 | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Trypanothione reductase | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Pleiotropic ABC efflux transporter of multiple drugs | 0 | 1 | 0 | 2 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Calmodulin | 0 | 0 | 1 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme 2 | 0 | 1 | 1 | 2 |
| Chloroquine resistance transporter | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Pyruvate kinase PKM | 0 | 0 | 1 | 1 |
| Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Amino acid transporter | 0 | 1 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |