| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 5 | 0 | 0 | 5 |
| RAR-related orphan receptor gamma | 7 | 0 | 0 | 7 |
| GLI family zinc finger 3 | 10 | 0 | 0 | 10 |
| AR protein | 13 | 0 | 0 | 13 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
| retinoid X nuclear receptor alpha | 7 | 0 | 0 | 7 |
| estrogen nuclear receptor alpha | 12 | 0 | 0 | 12 |
| peroxisome proliferator-activated receptor delta | 5 | 0 | 0 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 8 | 0 | 0 | 8 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform a | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 7 | 0 | 0 | 7 |
| lamin isoform A-delta10 | 5 | 0 | 0 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | 5 | 0 | 0 | 5 |
| Glutamate receptor 2 | 5 | 0 | 0 | 5 |
| Guanine deaminase | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 10 | 0 | 0 | 10 |
| pregnane X nuclear receptor | 7 | 0 | 0 | 7 |
| cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 6 | 0 | 6 |
| Multidrug resistance-associated protein 4 | 0 | 6 | 0 | 6 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 6 | 0 | 6 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 1 | 6 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 1 | 6 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 1 | 6 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 1 | 5 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 6 | 0 | 6 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| progesterone receptor | 7 | 0 | 0 | 7 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 8 | 0 | 0 | 8 |
| farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
| IDH1 | 4 | 0 | 0 | 4 |
| aryl hydrocarbon receptor | 7 | 0 | 0 | 7 |
| nuclear receptor subfamily 1, group I, member 2 | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 5 | 0 | 0 | 5 |
| galanin receptor type 3 | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 8 | 0 | 8 |
| Glycine receptor subunit alpha-1 | 0 | 8 | 0 | 8 |
| Glycine receptor subunit beta | 0 | 8 | 0 | 8 |
| Glycine receptor subunit alpha-2 | 0 | 8 | 0 | 8 |
| Glycine receptor subunit alpha-3 | 0 | 8 | 0 | 8 |
| ORF73 | 0 | 0 | 2 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| PINK1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 4 | 0 | 0 | 4 |
| Parkin | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 5 | 0 | 0 | 5 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| serine-protein kinase ATM isoform a | 1 | 0 | 0 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
| prostaglandin E2 receptor EP2 subtype | 0 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| geminin | 8 | 0 | 0 | 8 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 5 | 0 | 0 | 5 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| Carboxylic ester hydrolase | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 3 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 3 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 3 |
| Albumin | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 2 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 3 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 3 |
| Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 3 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 3 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
| 6-phosphogluconate dehydrogenase, decarboxylating | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Holo-[acyl-carrier-protein] synthase | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 1 | 0 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 3 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 3 |
| G-protein coupled receptor 35 | 0 | 1 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 3 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Luciferase | 2 | 0 | 0 | 2 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| WRN | 1 | 0 | 0 | 1 |
| integrase, partial | 0 | 1 | 0 | 1 |
| lens epithelium-derived growth factor p75 | 0 | 1 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 5 | 0 | 0 | 5 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| hexokinase-4 isoform 1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
| glucokinase regulatory protein | 1 | 0 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Polyphenol oxidase 2 | 0 | 0 | 0 | 1 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Plasma kallikrein | 0 | 0 | 0 | 1 |
| Tyrosine-protein kinase Lck | 0 | 1 | 0 | 1 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Tyrosinase | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 0 | 0 | 1 |
| Adenosine receptor A2a | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| SLC16A10 protein | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 0 | 1 |
| Monocarboxylate transporter 10 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 0 | 1 |
| phosphoglycerate kinase | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 4 | 0 | 0 | 4 |
| Ataxin-2 | 4 | 0 | 0 | 4 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 3 | 0 | 0 | 3 |
| GALC protein | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Glutamate 5-kinase | 0 | 0 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Amino acid transporter | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| procathepsin L isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |