Page last updated: 2024-11-11

beta-sitosterone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

beta-sitosterone: from Torreya jackii [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Torreyagenus[no description available]TaxaceaeA plant family of the order Pinales, class Pinopsida, division TRACHEOPHYTA.[MeSH]
Torreya jackiispecies[no description available]TaxaceaeA plant family of the order Pinales, class Pinopsida, division TRACHEOPHYTA.[MeSH]

Cross-References

ID SourceID
PubMed CID9801811
CHEMBL ID221543
SCHEMBL ID7164069
MeSH IDM0136643

Synonyms (8)

Synonym
beta-sitosterone
CHEMBL221543
SCHEMBL7164069
stigmast-5-en-3-one
51529-11-4
3-oxo-24-ethyl-cholest-5-ene
DTXSID50199498
bdbm50488934
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pathways (1)

PathwayProteinsCompounds
sitosterol degradation to androstenedione033

Bioassays (10)

Assay IDTitleYearJournalArticle
AID278000Antitubercular activity against Mycobacterium tuberculosis 90-2213872007Journal of natural products, Feb, Volume: 70, Issue:2
Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis.
AID422001Antiinflammatory activity in human neutrophils assessed as inhibition of fMet-Leu-Phe/Cytochalasin B-induced superoxide anion generation treated 5 mins before fMet-Leu-Phe/Cytochalasin B challenge by spectrophotometry2009Journal of natural products, Feb-27, Volume: 72, Issue:2
Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity.
AID606484Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay2011Journal of natural products, May-27, Volume: 74, Issue:5
Antituberculosis cycloartane triterpenoids from Radermachera boniana.
AID502769Cytotoxicity against human NCI-H460 cells after 72 hrs by MTS reduction assay2010Journal of natural products, Sep-24, Volume: 73, Issue:9
Cytotoxic flavonoids from the leaves of Cryptocarya chinensis.
AID502768Cytotoxicity against human MCF7 cells after 72 hrs by MTS reduction assay2010Journal of natural products, Sep-24, Volume: 73, Issue:9
Cytotoxic flavonoids from the leaves of Cryptocarya chinensis.
AID422404Antitubercular activity against Mycobacterium tuberculosis H37Rv after 2 weeks2009Journal of natural products, Feb-27, Volume: 72, Issue:2
seco-Abietane diterpenoids, a phenylethanoid derivative, and antitubercular constituents from Callicarpa pilosissima.
AID289114Inhibition of fMLP-induced superoxide production in human neutrophils2007Journal of natural products, Jun, Volume: 70, Issue:6
Anti-inflammatory benzenoids from Antrodia camphorata.
AID502770Cytotoxicity against human SF268 cells after 72 hrs by MTS reduction assay2010Journal of natural products, Sep-24, Volume: 73, Issue:9
Cytotoxic flavonoids from the leaves of Cryptocarya chinensis.
AID713897Antimycobacterial activity against Mycobacterium tuberculosis H37Rv2012European journal of medicinal chemistry, Mar, Volume: 49Recent advances in antitubercular natural products.
AID422002Antiinflammatory activity in human neutrophils assessed as inhibition of fMet-Leu-Phe/Cytochalasin B-induced elastase release treated 5 mins before fMet-Leu-Phe/Cytochalasin B challenge2009Journal of natural products, Feb-27, Volume: 72, Issue:2
Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.83

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.83 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.19 (4.65)
Search Engine Demand Index76.15 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (30.83)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]