| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| pregnane X receptor | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 5 | 0 | 0 | 5 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
| IDH1 | 4 | 0 | 0 | 4 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 4 | 0 | 0 | 4 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 4 | 0 | 0 | 4 |
| galanin receptor type 3 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Glucocorticoid receptor | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-1 | 0 | 6 | 0 | 6 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-2 | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-3 | 0 | 6 | 0 | 6 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| ORF73 | 0 | 0 | 1 | 1 |
| Chain A, Carbonic anhydrase II | 0 | 1 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
| ras protein, partial | 0 | 0 | 1 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| Smad3 | 2 | 0 | 0 | 2 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Rac1 protein | 0 | 0 | 1 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| interferon gamma precursor | 0 | 0 | 0 | 1 |
| prostaglandin E2 receptor EP2 subtype | 0 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| geminin | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 0 | 0 | 3 |
| Prostaglandin E synthase | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| Cytochrome c oxidase subunit 1 | 0 | 1 | 0 | 1 |
| Cytochrome c oxidase subunit 2 | 0 | 1 | 0 | 1 |
| Catechol O-methyltransferase | 0 | 1 | 0 | 1 |
| Cytochrome c oxidase subunit 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Procathepsin L | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 1 |
| Quinolone resistance protein NorA | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 0 | 0 | 3 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Calpain-2 catalytic subunit | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 0 | 0 | 3 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 0 | 0 | 3 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 0 | 0 | 3 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Cruzipain | 0 | 1 | 0 | 1 |
| Sodium/hydrogen exchanger 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 0 | 0 | 3 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 0 | 0 | 3 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 0 | 1 | 1 |
| Delta-type opioid receptor | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Bifunctional epoxide hydrolase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 1 | 4 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| Urotensin-2 receptor | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Histone deacetylase 4 | 0 | 1 | 0 | 1 |
| Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 0 | 0 | 3 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| Beta-carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Mitogen-activated protein kinase 14 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase, alpha family | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Delta carbonic anhydrase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| Cyclooxygenase-2 | 0 | 1 | 0 | 1 |
| Histone deacetylase 7 | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 3 | 0 | 0 | 3 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 2 | 0 | 2 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 12 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 0 | 0 | 3 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| Histone deacetylase 5 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| procathepsin L isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |