| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 2 | 4 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 6 | 0 | 0 | 1 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 1 | 3 |
| Sodium-dependent serotonin transporter | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 5A | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 5B | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 0 | 1 | 1 |
| Sodium-dependent dopamine transporter | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 4 | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | 0 | 0 | 1 | 1 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Hsf1 protein | 0 | 0 | 1 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| geminin | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 2 | 0 | 3 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | 0 | 0 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit rho-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 2 | 0 | 3 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent taurine transporter | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 1 | 2 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 1 | 2 |
| Sterol O-acyltransferase 1 | 0 | 0 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 0 | 1 | 1 |
| Histone deacetylase 7 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 2 | 0 | 3 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 2 | 0 | 3 |
| Platelet glycoprotein VI | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| Histone deacetylase 5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 1 | 0 | 1 |
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | 0 | 1 | 0 | 1 |
| Chain A, Glutamate Receptor Subunit 2 | 0 | 1 | 0 | 1 |
| Chain B, Glutamate Receptor Subunit 2 | 0 | 1 | 0 | 1 |
| Chain A, Slr1257 protein | 0 | 0 | 1 | 1 |
| Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| GLS protein | 3 | 0 | 0 | 3 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| AR protein | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| Metabotropic glutamate receptor 8 | 0 | 2 | 0 | 2 |
| Metabotropic glutamate receptor 6 | 0 | 1 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| Excitatory amino acid transporter 4 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Glutathione reductase, mitochondrial | 0 | 2 | 0 | 2 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | 0 | 1 | 0 | 1 |
| Prothrombin | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 1 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 0 | 0 | 1 |
| Integrin beta-3 | 0 | 0 | 1 | 1 |
| Integrin alpha-IIb | 0 | 0 | 1 | 1 |
| ATP-citrate synthase | 0 | 1 | 0 | 1 |
| Glutamate receptor 1 | 0 | 2 | 1 | 3 |
| Glutamate receptor 2 | 0 | 2 | 1 | 3 |
| Glutamate receptor 3 | 0 | 2 | 1 | 3 |
| Glutamate receptor 4 | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 1 | 0 | 2 | 1 | 3 |
| Metabotropic glutamate receptor 1 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 2 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 3 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 4 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 5 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 6 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 7 | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 1 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 5 | 0 | 1 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 2 | 0 | 2 | 1 | 3 |
| Glutamate receptor 1 | 0 | 2 | 1 | 3 |
| Glutamate receptor 2 | 0 | 2 | 1 | 3 |
| Glutamate receptor 3 | 0 | 1 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 2 | 0 | 2 |
| Excitatory amino acid transporter 1 | 0 | 2 | 0 | 3 |
| Excitatory amino acid transporter 2 | 0 | 2 | 0 | 3 |
| Excitatory amino acid transporter 3 | 0 | 2 | 0 | 3 |
| Metabotropic glutamate receptor 8 | 0 | 0 | 1 | 1 |
| Glutamate receptor 4 | 0 | 2 | 1 | 3 |
| Excitatory amino acid transporter 3 | 0 | 0 | 0 | 1 |
| Glutamate racemase | 0 | 0 | 0 | 1 |
| Metabotropic glutamate receptor 8 | 0 | 1 | 1 | 2 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 4 | 0 | 2 | 0 | 2 |
| Glutamate carboxypeptidase 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 2 | 0 | 1 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Metabotropic glutamate receptor 1 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 2 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 7 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 3 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 4 | 0 | 1 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 5 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 5 | 0 | 2 | 0 | 2 |
| Glutamate racemase | 0 | 0 | 0 | 1 |
| Prolyl 4-hydroxylase | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 2 | 1 | 3 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 2 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| Catechol O-methyltransferase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1E | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |