pukalide: structure in first source [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 21574603 |
| CHEMBL ID | 300390 |
| SCHEMBL ID | 1760554 |
| MeSH ID | M0415500 |
| Synonym |
|---|
| pukalide |
| CHEMBL300390 |
| SCHEMBL1760554 |
| methyl (2r,4s,6r,12s)-4-methyl-8-oxo-12-prop-1-en-2-yl-3,7,17-trioxatetracyclo[12.2.1.16,9.02,4]octadeca-1(16),9(18),14-triene-15-carboxylate |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID145335 | In vitro ability to inhibit the binding of [125I]alpha-bungarotoxin to nicotinic acetylcholine receptor on membranes prepared from the electric organs of Torpedo californica; Not active | 1991 | Journal of medicinal chemistry, Jun, Volume: 34, Issue:6 ISSN: 0022-2623 | Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| homarine | non-proteinogenic alpha-amino acid | 2007 | 2007 | 17.0 | high | 0 | 0 | 0 | 1 | 0 | 0 | ||
| furan | furans; mancude organic heteromonocyclic parent; monocyclic heteroarene | carcinogenic agent; hepatotoxic agent; Maillard reaction product | 2001 | 2017 | 15.0 | high | 0 | 0 | 0 | 1 | 1 | 0 | |
| perillyl alcohol | limonene monoterpenoid | plant metabolite; volatile oil component | 2017 | 2017 | 7.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
| lophotoxin | 2002 | 2002 | 22.0 | high | 0 | 0 | 0 | 1 | 0 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|