| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Dihydroorotate dehydrogenase | 0 | 1 | 0 | 1 |
| Protease | 0 | 1 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| AR protein | 6 | 0 | 0 | 6 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 7 | 0 | 0 | 7 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| IDH1 | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| galanin receptor type 3 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Glucocorticoid receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| ORF73 | 0 | 0 | 1 | 1 |
| Chain A, Estrogen-related receptor gamma | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, Estrogen-related receptor gamma | 0 | 0 | 1 | 1 |
| Chain A, Estrogen-related receptor gamma | 0 | 0 | 1 | 1 |
| Chain A, Estrogen-related receptor gamma | 0 | 0 | 1 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
| GALC protein | 1 | 0 | 0 | 1 |
| GLS protein | 3 | 0 | 0 | 3 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| importin subunit beta-1 isoform 1 | 2 | 0 | 0 | 2 |
| snurportin-1 | 2 | 0 | 0 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 1 | 0 | 3 |
| GTPase KRas | 0 | 0 | 1 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 1 | 3 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 1 | 0 | 3 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 1 | 0 | 3 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Estrogen-related receptor gamma | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 1 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 1 | 0 | 3 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| GTP-binding protein Rheb | 0 | 0 | 1 | 1 |
| GABA theta subunit | 2 | 1 | 0 | 3 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 1 | 0 | 3 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Chain A, Glycogen Phosphorylase | 0 | 1 | 0 | 1 |
| Chain A, Glycogen phosphorylase, liver form | 0 | 0 | 1 | 1 |
| Chain A, glycogen phosphorylase, liver form | 0 | 0 | 1 | 1 |
| Chain A, Glycogen phosphorylase, liver form | 0 | 0 | 1 | 1 |
| Chain A, Glycogen phosphorylase, liver form | 0 | 0 | 1 | 1 |
| Chain A, Chitinase | 0 | 1 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 3 | 0 | 0 | 3 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 1 | 1 | 2 |
| Glycogen phosphorylase, muscle form | 0 | 1 | 0 | 1 |
| Renin | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Glycogen phosphorylase, liver form | 0 | 1 | 0 | 1 |
| Glycogen phosphorylase, muscle form | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 2 | 0 | 3 |
| Amine oxidase [flavin-containing] B | 0 | 2 | 0 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 2 | 1 | 4 |
| Adenosine receptor A2b | 0 | 1 | 0 | 2 |
| Adenosine receptor A2b | 0 | 2 | 0 | 3 |
| Adenosine receptor A1 | 0 | 1 | 1 | 4 |
| Adenosine receptor A2a | 0 | 2 | 0 | 4 |
| Vasopressin V2 receptor | 0 | 0 | 0 | 1 |
| Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 0 | 1 | 0 | 1 |
| DNA-dependent protein kinase catalytic subunit | 0 | 1 | 0 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 1 | 0 | 0 | 0 | 1 |
| Chitotriosidase-1 | 0 | 1 | 0 | 1 |
| Serine-protein kinase ATM | 0 | 1 | 0 | 1 |
| Serine/threonine-protein kinase ATR | 0 | 1 | 0 | 1 |
| Adenosine receptor A2b | 0 | 1 | 0 | 2 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | 0 | 1 | 0 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | 0 | 1 | 2 | 3 |
| Endochitinase B1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 0 | 0 | 1 |
| Phosphodiesterase | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Guanine deaminase | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 2 |
| DNA gyrase subunit A | 0 | 1 | 0 | 3 |
| DNA gyrase subunit B | 0 | 1 | 0 | 3 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 2 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| DNA topoisomerase 2-alpha | 0 | 1 | 0 | 4 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Multidrug resistance protein MdtK | 0 | 0 | 1 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 3 | 0 | 4 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | 0 | 1 | 0 | 1 |
| Protein farnesyltransferase subunit beta | 0 | 1 | 0 | 1 |
| Glutaminyl-peptide cyclotransferase | 0 | 1 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Chain A, Immunoglobulin | 0 | 0 | 1 | 1 |
| Chain B, Immunoglobulin | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 2 |
| Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 0 | 1 | 2 |
| Delta-type opioid receptor | 0 | 0 | 0 | 1 |
| Kappa-type opioid receptor | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 0 | 2 |
| Lysosomal Pro-X carboxypeptidase | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 2 | 0 | 3 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 0 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 0 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 2 | 0 | 2 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Tyrosine-protein kinase Lck | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |