| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 4 | 0 | 0 | 4 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| G | 4 | 0 | 0 | 4 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| caspase-3 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 4 | 0 | 0 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 2 | 0 | 0 | 2 |
| ras-related protein Rab-9A | 2 | 0 | 0 | 2 |
| serine/threonine-protein kinase mTOR isoform 1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| geminin | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Interferon beta | 4 | 0 | 0 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | 4 | 0 | 0 | 4 |
| Albumin | 0 | 0 | 1 | 1 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 5 | 0 | 5 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 4 | 0 | 4 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 3 | 0 | 3 |
| Muscarinic acetylcholine receptor M1 | 0 | 4 | 0 | 4 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 4 | 0 | 4 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 4 | 0 | 4 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 4 | 2 | 6 |
| Sodium-dependent dopamine transporter | 0 | 4 | 0 | 4 |
| Potassium voltage-gated channel subfamily C member 1 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 4 | 3 | 7 |
| Sodium-dependent serotonin transporter | 0 | 4 | 1 | 5 |
| Cytochrome P450 2C19 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 4 | 0 | 0 | 4 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Gastrin/cholecystokinin type B receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 4 | 2 | 6 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 4 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 0 | 1 |
| Cytochrome P450 1B1 | 0 | 1 | 0 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Transporter | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 4 | 0 | 4 |
| Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 4 | 0 | 0 | 4 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Sigma non-opioid intracellular receptor 1 | 0 | 4 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| Transporter | 0 | 3 | 0 | 3 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 4 | 0 | 0 | 4 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| GALC protein | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| PINK1 | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| Parkin | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 4 | 1 | 5 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Androgen receptor | 0 | 4 | 0 | 4 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Estrogen receptor | 0 | 1 | 1 | 2 |
| Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
| Progesterone receptor | 0 | 2 | 1 | 3 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 2 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Androgen receptor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 0 | 1 | 1 |
| Quinolone resistance protein NorA | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Beta-adrenergic receptor kinase 1 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 3 | 0 | 1 | 0 | 1 |
| Beta-adrenergic receptor kinase 1 | 0 | 1 | 1 | 2 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Rhodopsin kinase GRK1 | 0 | 1 | 0 | 1 |
| G protein-coupled receptor kinase 5 | 0 | 1 | 0 | 1 |
| G protein-coupled receptor kinase 5 | 0 | 1 | 0 | 1 |
| P2X purinoceptor 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Envelope glycoprotein | 0 | 0 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Rhodopsin kinase GRK1 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| P2X purinoceptor 4 | 0 | 1 | 0 | 1 |
| Beta-adrenergic receptor kinase 1 | 0 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| Cocaine esterase | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
| Tissue factor | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 2 |
| UDP-glucuronosyltransferase 1-6 | 0 | 0 | 0 | 1 |
| Liver carboxylesterase 1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 4 | 0 | 2 | 0 | 2 |
| Histone deacetylase 1 | 0 | 2 | 0 | 2 |
| Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B7 | 0 | 1 | 0 | 1 |
| Histone deacetylase 7 | 0 | 2 | 0 | 2 |
| Histone deacetylase 2 | 0 | 2 | 0 | 2 |
| Polyamine deacetylase HDAC10 | 0 | 2 | 0 | 2 |
| Histone deacetylase 11 | 0 | 2 | 0 | 2 |
| Histone deacetylase 8 | 0 | 2 | 0 | 2 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
| Histone deacetylase 6 | 0 | 2 | 0 | 2 |
| Histone deacetylase 9 | 0 | 2 | 0 | 2 |
| Histone deacetylase 5 | 0 | 2 | 0 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |