| Assay ID | Title | Year | Journal | Article |
|---|
| AID92009 | In vitro inhibition of human Inducible nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| AID316796 | Selectivity for human nNOS to human iNOS | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID600731 | Inhibition of human recombinant eNOS by microtiter plate assay | 2011 | Bioorganic & medicinal chemistry letters, May-15, Volume: 21, Issue:10
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. |
| AID146136 | Ratio of binding to Neuronal nitric oxide synthase and Inducible nitric oxide synthase | 2000 | Bioorganic & medicinal chemistry letters, Mar-20, Volume: 10, Issue:6
| Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine. |
| AID607320 | Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
| AID316798 | Inhibition of cytokine-induced iNOS activity in human DLD1 cells at 10 uM after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID600732 | Inhibition of human recombinant nNOS by microtiter plate assay | 2011 | Bioorganic & medicinal chemistry letters, May-15, Volume: 21, Issue:10
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. |
| AID607322 | Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
| AID68141 | In vitro inhibition of human endothelial nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| AID67823 | Ratio of Endothelial Nitric Oxide Synthase to Inducible nitric oxide synthase | 2000 | Bioorganic & medicinal chemistry letters, Mar-20, Volume: 10, Issue:6
| Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine. |
| AID316792 | Inhibition of human iNOS expressed in human DLD1 cells after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID91995 | Inhibition of human inducible nitric oxide synthase | 2000 | Bioorganic & medicinal chemistry letters, Mar-20, Volume: 10, Issue:6
| Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine. |
| AID600733 | Selectivity index, ratio of IC50 for human recombinant iNOS to IC50 for human recombinant eNOS | 2011 | Bioorganic & medicinal chemistry letters, May-15, Volume: 21, Issue:10
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. |
| AID600734 | Selectivity index, ratio of IC50 for human recombinant iNOS to IC50 for human recombinant nNOS | 2011 | Bioorganic & medicinal chemistry letters, May-15, Volume: 21, Issue:10
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. |
| AID316800 | Inhibition of human eNOS expressed in insect SF9 cells at 10 uM after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID146106 | Inhibition of human neuronal Nitric Oxide Synthase | 2000 | Bioorganic & medicinal chemistry letters, Mar-20, Volume: 10, Issue:6
| Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine. |
| AID218912 | Inhibition of human endothelial Nitric Oxide Synthase | 2000 | Bioorganic & medicinal chemistry letters, Mar-20, Volume: 10, Issue:6
| Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine. |
| AID600730 | Inhibition of human recombinant iNOS by microtiter plate assay | 2011 | Bioorganic & medicinal chemistry letters, May-15, Volume: 21, Issue:10
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. |
| AID316794 | Inhibition of human nNOS expressed in insect SF9 cells after 1 hr | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID316795 | Selectivity for human eNOS to human iNOS | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1
| Discovery of a series of aminopiperidines as novel iNOS inhibitors. |
| AID607321 | Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. |
| AID146120 | In vitro inhibition of human neuronal nitric oxide synthase. | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| AID1345147 | Human Endothelial NOS (Nitric oxide synthases) | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| AID1345253 | Human Neuronal NOS (Nitric oxide synthases) | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| AID1345216 | Human Inducible NOS (Nitric oxide synthases) | 2004 | Journal of medicinal chemistry, Jun-03, Volume: 47, Issue:12
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |