| Assay ID | Title | Year | Journal | Article |
|---|
| AID9983 | MDR-reversing activity was measured by vincristine accumulation in the multidrug resistant 2780AD, a subline of A2780 ovarian carcinoma cells at 10 mg/mL | 2000 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 10, Issue:2
| Synthesis and biological activities of hapalosin derivatives with modification at the C12 position. |
| AID82676 | Inhibitory concentration against HL-60/ADR cells using MRP-mediated MDR assay using 2 nM vincristine which inhibits cell proliferation by 20% in the absence of particular cytotoxic drug | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Design, synthesis, and evaluation of the multidrug resistance-reversing activity of D-glucose mimetics of hapalosin. |
| AID154133 | Multidrug-resistant reversal activity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycoprotein) in the presence of 10 nM vincristine | 1999 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 9, Issue:11
| Synthesis and evaluation of hapalosin and analogs as MDR-reversing agents. |
| AID103928 | Inhibitory concentration against MCF-7/ADR cells using P-gp-mediated MDR assay using 25 nM actinomycin D which inhibits cell proliferation by 20% in the absence of particular cytotoxic drug | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Design, synthesis, and evaluation of the multidrug resistance-reversing activity of D-glucose mimetics of hapalosin. |
| AID85445 | Compound was tested for the induction of apoptosis in human fibrosarcoma HT1080 cell line; No induction of apoptosis up to 10 ug/mL | 2000 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 10, Issue:2
| Synthesis and biological activities of hapalosin derivatives with modification at the C12 position. |
| AID103923 | Effective concentration against MCF-7/ADR cells using P-gp-mediated MDR assay using 25 nM actinomycin D which results in 50% of the cells being killed in the presence of particular cytotoxic drug. | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Design, synthesis, and evaluation of the multidrug resistance-reversing activity of D-glucose mimetics of hapalosin. |
| AID229315 | Ratio of IC50 of cytotoxicity to the IC50 of MDR- reversal for P388/VMDRC.04 cells | 1999 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 9, Issue:11
| Synthesis and evaluation of hapalosin and analogs as MDR-reversing agents. |
| AID82675 | Effective concentration against HL-60/ADR cells using MRP-mediated MDR assay using 2 nM vincristine which results in 50% of the cells being killed in the presence of particular cytotoxic drug. | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Design, synthesis, and evaluation of the multidrug resistance-reversing activity of D-glucose mimetics of hapalosin. |
| AID154132 | Evaluated for cytotoxicity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycoprotein) in the absence of 10 nM vincristine | 1999 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 9, Issue:11
| Synthesis and evaluation of hapalosin and analogs as MDR-reversing agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |