Page last updated: 2024-09-03

statine and primaquine

statine has been researched along with primaquine in 2 studies

Compound Research Comparison

Studies (statine)	Trials (statine)	Recent Studies (post-2010) (statine)	Studies (primaquine)	Trials (primaquine)	Recent Studies (post-2010) (primaquine)
128	6	40	2,196	196	711

Protein Interaction Comparison

Protein	Taxonomy	primaquine (IC50)
Cytochrome P450 1A2	Homo sapiens (human)	0.1824
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	7.5
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.016
Serine hydroxymethyltransferase, mitochondrial	Homo sapiens (human)	0.4365
Thiosulfate sulfurtransferase	Homo sapiens (human)	2.9
60 kDa chaperonin	Escherichia coli	6.2
10 kDa chaperonin	Escherichia coli	6.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bosisio, E; Dell'Agli, M; Galli, G; Mondani, M; Parapini, S; Rizzi, L; Romeo, S; Sparatore, A; Taramelli, D	1
Clemente, J; Dunn, BM; Janka, L; Romeo, S; Sparatore, A; Vaiana, N	1

Other Studies

2 other study(ies) available for statine and primaquine

Article	Year
Plasmepsin II inhibition and antiplasmodial activity of Primaquine-Statine 'double-drugs'. Bioorganic & medicinal chemistry letters, 2004, Jun-07, Volume: 14, Issue:11 Topics: Amino Acids; Animals; Antimalarials; Aspartic Acid Endopeptidases; Chloroquine; Cross-Linking Reagents; Drug Design; Drug Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Primaquine; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship	2004
Targeting the plasmepsin 4 orthologs of Plasmodium sp. with "double drug" inhibitors. Protein and peptide letters, 2008, Volume: 15, Issue:9 Topics: Amino Acids; Animals; Antimalarials; Aspartic Acid Endopeptidases; Chromatography, Affinity; Chromatography, Gel; Enzyme Precursors; Gene Expression; Inclusion Bodies; Models, Molecular; Plasmodium; Primaquine; Protease Inhibitors; Protein Renaturation; Protozoan Proteins; Vacuoles	2008

Article

Year

Plasmepsin II inhibition and antiplasmodial activity of Primaquine-Statine 'double-drugs'.

Bioorganic & medicinal chemistry letters, 2004, Jun-07, Volume: 14, Issue:11

Topics: Amino Acids; Animals; Antimalarials; Aspartic Acid Endopeptidases; Chloroquine; Cross-Linking Reagents; Drug Design; Drug Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Primaquine; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship

2004

Targeting the plasmepsin 4 orthologs of Plasmodium sp. with "double drug" inhibitors.

Protein and peptide letters, 2008, Volume: 15, Issue:9

Topics: Amino Acids; Animals; Antimalarials; Aspartic Acid Endopeptidases; Chromatography, Affinity; Chromatography, Gel; Enzyme Precursors; Gene Expression; Inclusion Bodies; Models, Molecular; Plasmodium; Primaquine; Protease Inhibitors; Protein Renaturation; Protozoan Proteins; Vacuoles

2008