Compounds > sesone

Page last updated: 2024-08-20

sesone and 6-amino-5-bromouracil

sesone has been researched along with 6-amino-5-bromouracil in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (10.00)	18.2507
2000's	6 (60.00)	29.6817
2010's	3 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Balzarini, J; Camarasa, MJ; De Clercq, E; Esnouf, R; Esteban-Gamboa, A; Pérez-Pérez, MJ	1
Bryce, RA; Douglas, KT; Freeman, S; Gbaj, A; Jaffar, M; McNally, VA; Stratford, IJ	1
Chinje, E; Douglas, KT; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ	1
Ashton, SE; Barry, ST; Bryce, RA; Cole, C; Douglas, KT; Edwards, PN; Freeman, S; Gbaj, A; Jaffar, M; Luke, RW; Page, KM; Reigan, P; Stratford, IJ	1
Bryce, RA; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ	1
Bera, H; Chiu, GN; Chui, WK; Dolzhenko, AV; Li, J; Sun, L	1
Bera, H; Chigurupati, S	1
Basso, LA; Bergo, P; Campos, MM; da Silva Dadda, A; de Moura Sperotto, ND; Deves Roth, C; Duarte de Souza, AP; Ev Neves, C; Freitas de Freitas, T; Machado, P; Moura, S; Reisdorfer Paula, F; Rodrigues-Junior, VS; Santos, DS; Souza Macchi, F; Valim Bizarro, C	1
Balzarini, J; Camarasa, MJ; De Clercq, E; Esnouf, R; Gamboa, AE; Liekens, S; Neyts, J; Pérez-Pérez, MJ	1
Balzarini, J; Camarasa, MJ; De Clercq, E; Degrève, B; Engelborghs, Y; Esnouf, R; Esteban-Gamboa, A; Pérez-Pérez, MJ	1

Reviews

1 review(s) available for sesone and 6-amino-5-bromouracil

Article	Year
Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer. European journal of medicinal chemistry, 2016, Nov-29, Volume: 124 Topics: Animals; Antineoplastic Agents; Carcinogenesis; Drug Discovery; Enzyme Inhibitors; Humans; Neoplasms; Thymidine Phosphorylase	2016

Other Studies

9 other study(ies) available for sesone and 6-amino-5-bromouracil

Article	Year
Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase. Journal of medicinal chemistry, 2000, Mar-09, Volume: 43, Issue:5 Topics: Chromatography, High Pressure Liquid; Drug Design; Enzyme Inhibitors; Escherichia coli; Kinetics; Models, Molecular; Organophosphonates; Pyrimidinones; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase; Uracil	2000
Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening. Bioorganic & medicinal chemistry letters, 2003, Nov-03, Volume: 13, Issue:21 Topics: Binding Sites; Computer Simulation; Crystallography, X-Ray; Databases, Genetic; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Humans; Hydrazines; Imidazoles; Kinetics; Models, Molecular; Recombinant Proteins; Structure-Activity Relationship; Thymidine; Thymidine Phosphorylase	2003
Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase. Bioorganic & medicinal chemistry letters, 2004, Nov-01, Volume: 14, Issue:21 Topics: Antineoplastic Agents; Escherichia coli; Humans; Prodrugs; Pyrimidines; Pyrroles; Pyrrolidines; Thymidine Phosphorylase; Xanthine Oxidase	2004
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Availability; Escherichia coli; Humans; Imidazoles; Mice; Models, Molecular; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Structure-Activity Relationship; Thymidine Phosphorylase; Uracil	2005
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. European journal of medicinal chemistry, 2008, Volume: 43, Issue:6 Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Prodrugs; Spectrophotometry, Infrared; Thymidine Phosphorylase; Xanthine Oxidase	2008
Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors. European journal of medicinal chemistry, 2013, Volume: 70 Topics: Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Molecular Structure; Pyrazines; Structure-Activity Relationship; Thymidine Phosphorylase; Triazines; Uracil	2013
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Glioblastoma; Half-Life; Humans; Thymidine Phosphorylase	2019
7-Deazaxanthine, a novel prototype inhibitor of thymidine phosphorylase. FEBS letters, 1998, Oct-30, Volume: 438, Issue:1-2 Topics: Allantois; Animals; Antibiotics, Antineoplastic; Binding Sites; Bromouracil; Chick Embryo; Chorion; Cyclohexanes; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Escherichia coli; Neovascularization, Physiologic; O-(Chloroacetylcarbamoyl)fumagillol; Sesquiterpenes; Thymidine; Thymidine Phosphorylase; Thymine; Xanthines	1998
Kinetic analysis of novel multisubstrate analogue inhibitors of thymidine phosphorylase. FEBS letters, 2000, Oct-20, Volume: 483, Issue:2-3 Topics: Bromouracil; Enzyme Inhibitors; Escherichia coli; Kinetics; Models, Molecular; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase; Thymine; Xanthines	2000