sesone has been researched along with 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chinje, E; Douglas, KT; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ | 1 |
| Ashton, SE; Barry, ST; Bryce, RA; Cole, C; Douglas, KT; Edwards, PN; Freeman, S; Gbaj, A; Jaffar, M; Luke, RW; Page, KM; Reigan, P; Stratford, IJ | 1 |
| Bryce, RA; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ | 1 |
| Ambreen, N; Choudhary, MI; Hussain, S; Khan, KM; Perveen, S | 1 |
| Bera, H; Chui, WK; Sun, L | 1 |
| Bera, H; Chiu, GN; Chui, WK; Dolzhenko, AV; Li, J; Sun, L | 1 |
| Bera, H; Chigurupati, S | 1 |
| Jin, Y; Li, K; Lin, J; Zhao, S | 1 |
| Ali, M; Imran, S; Rashid, U; Taha, M | 1 |
1 review(s) available for sesone and 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride
| Article | Year |
|---|---|
Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; Drug Discovery; Enzyme Inhibitors; Humans; Neoplasms; Thymidine Phosphorylase | 2016 |
8 other study(ies) available for sesone and 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride
| Article | Year |
|---|---|
Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.
Topics: Antineoplastic Agents; Escherichia coli; Humans; Prodrugs; Pyrimidines; Pyrroles; Pyrrolidines; Thymidine Phosphorylase; Xanthine Oxidase | 2004 |
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Availability; Escherichia coli; Humans; Imidazoles; Mice; Models, Molecular; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Structure-Activity Relationship; Thymidine Phosphorylase; Uracil | 2005 |
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Prodrugs; Spectrophotometry, Infrared; Thymidine Phosphorylase; Xanthine Oxidase | 2008 |
Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors.
Topics: Chromones; Enzyme Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Schiff Bases; Spectrophotometry, Infrared; Structure-Activity Relationship; Thymidine Phosphorylase | 2009 |
Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Molecular Structure; Pyrazines; Recombinant Proteins; Structure-Activity Relationship; Thymidine Phosphorylase; Triazines | 2013 |
Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Molecular Structure; Pyrazines; Structure-Activity Relationship; Thymidine Phosphorylase; Triazines; Uracil | 2013 |
Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
Topics: Angiogenesis Inhibitors; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Oximes; Structure-Activity Relationship; Thymidine Phosphorylase; Uracil | 2018 |
Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase.
Topics: Binding Sites; Catalytic Domain; Drug Design; Enzyme Inhibitors; Escherichia coli; Humans; Hydrogen Bonding; Methane; Molecular Docking Simulation; Oxadiazoles; Structure-Activity Relationship; Thymidine Phosphorylase | 2018 |