5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride profile

tipiracil hydrochloride : A hydrochloride obtained by combining tipiracil with one equivalent of hydrochloric acid. Used in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	9903778
CHEMBL ID	65375
CHEBI ID	90877
SCHEMBL ID	1682924
MeSH ID	M0304941

Synonym
chembl65375 ,
tas-1-462
tipiracil hydrochloride
S3731
unii-4h59klq0a4
4h59klq0a4 ,
tipiracil hydrochloride [usan]
183204-72-0
tipiracil hydrochloride (jan/usan)
D10467
tipiracil hydrochloride [mi]
tipiracil hydrochloride [who-dd]
tas-102 component tipiracil hydrochloride
s-95005 component tipiracil hydrochloride
5-chloro-6-(2-imino-pyrrolidin-1-yl)methyl-2,4(1h,3h)-pyrimidinedione hydrochloride
2,4(1h,3h)-pyrimidinedione, 5-chloro-6-((2-imino-1-pyrrolidinyl)methyl)-, hydrochloride (1:1)
lonsurf component tipiracil hydrochloride
tipiracil hydrochloride [jan]
tipiracil hydrochloride component of lonsurf
tipiracil hydrochloride [orange book]
HY-A0063
tipiracil (hydrochloride)
CS-1637
5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride
5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4-(1h,3h)-pyrimidinedione hydrochloride
KGHYQYACJRXCAT-UHFFFAOYSA-N
5-chloro-6-(1-(2-iminopyrrolidinyl)-methyl)uracil hydrochloride
5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1h,3h)-pyrimidinedione hydrochloride
1-[(5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]pyrrolidin-2-iminium chloride
tipiracil.hcl
5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1h,3h)-dione hydrochloride
CHEBI:90877
tipiracil monohydrochloride
SCHEMBL1682924
tipiracil hcl
AC-30634
J-690251
EX-A882
ma-1 hydrochloride
AKOS027427002
5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1h,3h)-dione hydrochloride
tipiracil hydrochloride, >=98% (hplc)
FT-0700247
BCP06245
Q27162848
5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1h-pyrimidine-2,4-dione;hydrochloride
EX-A1393
mfcd01571384
5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1h,3h)-dione hcl
AMY25415
CCG-267234
AS-56082
A847265
5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1h,3h)-dione hydrochloride;tipiracil hcl
DTXSID001027748
5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1h,3h)-dionehydrochloride

Role	Description
antineoplastic agent	A substance that inhibits or prevents the proliferation of neoplasms.
EC 2.4.2.4 (thymidine phosphorylase) inhibitor	An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of thymidine phosphorylase (EC 2.4.2.4).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
hydrochloride	A salt formally resulting from the reaction of hydrochloric acid with an organic base.
iminium salt	Salts in which the cation has the structure R2C=N(+)R2. Thus N-hydronated imines and their N-substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Thymidine phosphorylase	Escherichia coli K-12	IC50 (µMol)	0.0227	0.0027	1.7914	6.5000	AID1055574; AID241246; AID241389; AID415489; AID589642
Thymidine phosphorylase	Homo sapiens (human)	IC50 (µMol)	0.0314	0.0200	1.5838	6.8000	AID1055579; AID1335972; AID1402655; AID1402656; AID1497670; AID213303; AID241061; AID363294; AID757420
Thymidine phosphorylase	Homo sapiens (human)	Ki	0.0190	0.0013	0.2704	2.6000	AID238361; AID363294; AID456853
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
DNA damage response	Thymidine phosphorylase	Escherichia coli K-12
pyrimidine nucleobase metabolic process	Thymidine phosphorylase	Escherichia coli K-12
pyrimidine nucleoside metabolic process	Thymidine phosphorylase	Escherichia coli K-12
thymidine metabolic process	Thymidine phosphorylase	Escherichia coli K-12
mitochondrial genome maintenance	Thymidine phosphorylase	Homo sapiens (human)
angiogenesis	Thymidine phosphorylase	Homo sapiens (human)
pyrimidine nucleobase metabolic process	Thymidine phosphorylase	Homo sapiens (human)
pyrimidine nucleoside metabolic process	Thymidine phosphorylase	Homo sapiens (human)
chemotaxis	Thymidine phosphorylase	Homo sapiens (human)
signal transduction	Thymidine phosphorylase	Homo sapiens (human)
cell differentiation	Thymidine phosphorylase	Homo sapiens (human)
regulation of myelination	Thymidine phosphorylase	Homo sapiens (human)
dTMP catabolic process	Thymidine phosphorylase	Homo sapiens (human)
regulation of transmission of nerve impulse	Thymidine phosphorylase	Homo sapiens (human)
regulation of gastric motility	Thymidine phosphorylase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
1,4-alpha-oligoglucan phosphorylase activity	Thymidine phosphorylase	Escherichia coli K-12
thymidine phosphorylase activity	Thymidine phosphorylase	Escherichia coli K-12
glycosyltransferase activity	Thymidine phosphorylase	Escherichia coli K-12
pentosyltransferase activity	Thymidine phosphorylase	Escherichia coli K-12
1,4-alpha-oligoglucan phosphorylase activity	Thymidine phosphorylase	Homo sapiens (human)
protein binding	Thymidine phosphorylase	Homo sapiens (human)
growth factor activity	Thymidine phosphorylase	Homo sapiens (human)
thymidine phosphorylase activity	Thymidine phosphorylase	Homo sapiens (human)
protein homodimerization activity	Thymidine phosphorylase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
cytosol	Thymidine phosphorylase	Escherichia coli K-12
membrane	Thymidine phosphorylase	Escherichia coli K-12
cytosol	Thymidine phosphorylase	Escherichia coli K-12
cytosol	Thymidine phosphorylase	Homo sapiens (human)
cytosol	Thymidine phosphorylase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (41)

Assay ID	Title	Year	Journal	Article
AID1055579	Competitive inhibition of human thymidine phosphorylase in presence of thymidine	2013	European journal of medicinal chemistry, , Volume: 70	Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
AID1402662	Antiangiogenic activity against human HUVEC assessed as inhibition of capillary/tube-like network formation at 0.05 uM after 20 to 40 hrs by microscopic analysis	2018	European journal of medicinal chemistry, Jan-20, Volume: 144	Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
AID236065	Bioavailability in mouse (dose 20 mg/kg p.o.)	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID237024	Steady state volume of distribution was measured in mice after intraperitoneal administration of 10 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236740	Maximum concentration was measured in mice after intravenous administration of 2 mg/kg; N/A = not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236983	Maximum time to attain Cmax in mice after intravenous administration of 2 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID1335972	Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting method	2016	European journal of medicinal chemistry, Nov-29, Volume: 124	Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer.
AID236154	Concentration at time 0 was measured in mice after oral administration of 20 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236438	Area under concentration-time curve for the compound was measured in mice after oral administration of 20 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236115	Bioavailability in mouse (dose 2 mg/kg i.v.)	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236968	Maximum time to attain Cmax in mice after oral administration of 20 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID456853	Inhibition of human recombinant thymidine phosphorylase	2010	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3	Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
AID363294	Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assay	2008	European journal of medicinal chemistry, Jun, Volume: 43, Issue:6	Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
AID236153	Concentration at time 0 was measured in mice after intravenous administration of 2 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID1402655	Inhibition of human placental thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting analysis	2018	European journal of medicinal chemistry, Jan-20, Volume: 144	Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
AID237022	Steady state volume of distribution was measured in mice after intravenous administration of 2 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236977	Maximum time to attain Cmax in mice after intraperitoneal administration of 10 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID589642	Inhibition of Escherichia coli Thymidine phosphorylase by spectrophotometry	2011	European journal of medicinal chemistry, Apr, Volume: 46, Issue:4	Structure-activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase.
AID415489	Inhibition of Escherichia coli thymidine phosphorylase	2009	Bioorganic & medicinal chemistry, Apr-15, Volume: 17, Issue:8	Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors.
AID241246	Inhibition of Thymidine phosphorylase from Escherichia coli	2004	Bioorganic & medicinal chemistry letters, Nov-01, Volume: 14, Issue:21	Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.
AID238361	Inhibitory activity against thymidine phosphorylase	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID1055574	Inhibition of Escherichia coli recombinant thymidine phosphorylase using thymidine as substrate after 4 to 20 mins by UV spectrophotometry	2013	European journal of medicinal chemistry, , Volume: 70	Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
AID236098	Bioavailability in mouse (dose 10 mg/kg i.p.)	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236947	Half-life was measured in mice after intravenous administration of 2 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID757420	Inhibition of human thymidine phosphorylase	2013	European journal of medicinal chemistry, Jul, Volume: 65	Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase.
AID236256	Clearance at time 0 was measured in mice after intravenous administration of 2 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID241389	Inhibitory concentration against thymidine phosphorylase of Escherichia coli	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236950	Half-life was measured in mice after intraperitoneal administration of 10 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236655	Maximum plasma concentration in mice after oral administration of 20 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID241061	Inhibitory concentration against human thymidine phosphorylase	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236259	Clearance at time 0 was measured in mice after oral administration of 20 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236263	Clearance at time 0 was measured in mice after intraperitoneal administration of 10 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID237023	Steady state volume of distribution was measured in mice after oral administration of 20 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID1402656	Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysis	2018	European journal of medicinal chemistry, Jan-20, Volume: 144	Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
AID236460	Area under concentration-time curve for the compound was measured in mice after intravenous administration of 2 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID213303	Compound was evaluated for its inhibitory activity against recombinant purified Escherichia coli Thymidine Phosphorylase	2003	Journal of medicinal chemistry, Jan-16, Volume: 46, Issue:2	Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.
AID236943	Half-life was measured in mice after oral administration of 20 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236155	Concentration at time 0 was measured in mice after intraperitoneal administration of 10 mg/kg; not available	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236469	Area under concentration-time curve for the compound was measured in mice after intraperitoneal administration of 10 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID236707	Maximum concentration was measured in mice after intraperitoneal administration of 10 mg/kg	2005	Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2	Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
AID1497670	Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting method	2018	Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12	Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (41.67)	29.6817
2010's	7 (58.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (8.33%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	11 (91.67%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
xanthine 7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.. 9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.	2.04	1	xanthine	Saccharomyces cerevisiae metabolite
thymidine [no description available]	2.44	2	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite
cycloheximide Cycloheximide: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.. cycloheximide : A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.	2.17	1	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor
6-aminothymine 6-aminothymine: inhibits degradation of nucleosides (idoxuridine, thymidine) & pyrimidine bases	3.61	2
5-bromocytosine [no description available]	2.43	2
6-amino-5-bromouracil [no description available]	4.39	6
5-nitro-2'-deoxyuridine [no description available]	2.44	2
5-phenyl-1,3,4-oxadiazole-2-thiol 5-phenyl-1,3,4-oxadiazole-2-thiol: structure in first source	3.23	1
sesone 7-deazaxanthine: structure in first source	4.78	9
3,n(4)-ethanocytosine [no description available]	2.04	1	organic heterobicyclic compound	mutagen
5'-o-tritylinosine 5'-O-tritylinosine: structure in first source	2.08	1

Condition	Relationship Strength	Studies
T-Cell Lymphoma [description not available]	2.05	1
Lymphoma, T-Cell A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.	2.05	1
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.	3.04	1
Benign Neoplasms [description not available]	3.04	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	3.04	1

5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride

Description

Cross-References

Synonyms (56)

Roles (2)

Drug Classes (2)

Protein Targets (2)

Inhibition Measurements

Biological Processes (13)

Molecular Functions (7)

Ceullar Components (2)

Bioassays (41)

Research

Studies (12)

Market Indicators

Research Demand Index: 11.94

Study Types

5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride

Description

Cross-References

Synonyms (56)

Roles (2)

Drug Classes (2)

Protein Targets (2)

Inhibition Measurements

Biological Processes (13)

Molecular Functions (7)

Ceullar Components (2)

Bioassays (41)

Research

Studies (12)

Market Indicators

Research Demand Index: 11.94

Study Types

Related Drugs (11)

Related Conditions (5)