methandriol and Uterine-Neoplasms

methandriol has been researched along with Uterine-Neoplasms* in 3 studies

Trials

1 trial(s) available for methandriol and Uterine-Neoplasms

Article	Year
The use of a biological preparation in the treatment of some gynaecological diseases. Current medical research and opinion, 1976, Volume: 4, Issue:2 A double-blind between-patient trial was carried out in 200 women suffering from dysfunctional menorrhagia (142) or from menorrhagia associated with uterine fibromyomatosis (58) to assess and compare the effectiveness of a polypeptide preparation ('Lysometra') and methylandrostendiol in reducing hyperoestrogenism and clinical symptoms. Three 20-day courses of intramuscular injections of either 2.5 ml 'Lysometra' or 5 mg methylandrostendiol were given to matched pairs of patients, with an 8-day interval between. Results, as assessed by absolute and percentage changes in total urine oestrogen levels and by overall clinical response of patients, showed that 'Lysometra' produced a statistically significant greater effect than methylandrostendiol. The biological preparation was well tolerated and no unwanted side-effects were reported. Topics: Androstenediols; Clinical Trials as Topic; Estrogens; Female; Humans; Injections, Intramuscular; Leiomyoma; Menorrhagia; Methandriol; Peptides; Uterine Neoplasms	1976

Article

Year

The use of a biological preparation in the treatment of some gynaecological diseases.

Current medical research and opinion, 1976, Volume: 4, Issue:2

A double-blind between-patient trial was carried out in 200 women suffering from dysfunctional menorrhagia (142) or from menorrhagia associated with uterine fibromyomatosis (58) to assess and compare the effectiveness of a polypeptide preparation ('Lysometra') and methylandrostendiol in reducing hyperoestrogenism and clinical symptoms. Three 20-day courses of intramuscular injections of either 2.5 ml 'Lysometra' or 5 mg methylandrostendiol were given to matched pairs of patients, with an 8-day interval between. Results, as assessed by absolute and percentage changes in total urine oestrogen levels and by overall clinical response of patients, showed that 'Lysometra' produced a statistically significant greater effect than methylandrostendiol. The biological preparation was well tolerated and no unwanted side-effects were reported.

Topics: Androstenediols; Clinical Trials as Topic; Estrogens; Female; Humans; Injections, Intramuscular; Leiomyoma; Menorrhagia; Methandriol; Peptides; Uterine Neoplasms

1976

Other Studies

2 other study(ies) available for methandriol and Uterine-Neoplasms

Article	Year
[Use of prednisone with methylandrostenediol in advanced uterine cancer]. Minerva ginecologica, 1956, Jul-15, Volume: 8, Issue:13 Topics: Androgens; Female; Humans; Methandriol; Neoplasms; Prednisone; Uterine Neoplasms	1956
[Changes in adrenal cortex function after methylandrostenediol therapy of uterine cancer]. Minerva ginecologica, 1955, Jun-30, Volume: 7, Issue:12 Topics: Adrenal Cortex; Androgens; Female; Humans; Methandriol; Uterine Neoplasms	1955