bindarit has been researched along with Disease Models, Animal in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Berta, T; Brown, FN; Campbell, K; Goto, J; Iwasawa, E; Kahn, F; Ladle, DR; Lee, SH; Mangano, FT; Shula, C | 1 |
| Cai, C; Kilari, S; Misra, S; Singh, AK | 1 |
| Chao, W; Gu, CJ; Hadas, E; Kelschenbach, J; Kim, BH; Potash, MJ; Volsky, DJ | 1 |
| Huang, X; Li, H; Li, L; Lou, W; Zhu, Y | 1 |
| Chi, ZF; Kang, AL; Liu, YX; Nie, LH; Niu, CY; Wang, P; Wang, Q; Wei, D; Zhang, H; Zhang, LM; Zhao, M; Zhao, ZA; Zhao, ZG | 1 |
| Gao, C; Gao, H; Liu, S; Liu, W; Xing, D | 1 |
| Frank, JA; Luo, J; Wang, H; Xu, M; Zhang, K | 1 |
| Davis, JM; Guglielmotti, A; McClellan, JL; Murphy, EA; Steiner, JL | 1 |
| Chen, W; Foo, SS; Forwood, MR; Herrero, LJ; Hueston, L; Lulla, A; Mahalingam, S; Merits, A; Sims, NA; Taylor, A; Walsh, NC | 1 |
| Buelli, S; Corna, D; Guglielmotti, A; Locatelli, M; Morigi, M; Perico, N; Pezzotta, A; Remuzzi, A; Remuzzi, G; Rottoli, D; Zanchi, C; Zoja, C | 1 |
| Allegra, M; Bozzi, Y; Caleo, M; Cerri, C; Genovesi, S; Guglielmotti, A; Perry, VH; Pistillo, F; Püntener, U | 1 |
| Biondi, G; Grassia, G; Guglielmotti, A; Ialenti, A; Maddaluno, M; Maffia, P; Mangano, G | 1 |
| Apicella, C; Guglielmotti, A; Mahalingam, S; Mangano, G; Rolph, MS; Rulli, NE; Suhrbier, A; Zaid, A | 1 |
| Chade, AR; Daghini, E; Guglielmotti, A; Krier, JD; Lavi, R; Lerman, A; Lerman, LO; Zhu, XY | 1 |
| Bhatia, M; Chevali, L; Guglielmotti, A; Ramnath, RD | 1 |
16 other study(ies) available for bindarit and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Disease Models, Animal; Female; Humans; Hydrocephalus; Indazoles; Mice; Microglia; Pregnancy; Propionates | 2022 |
Bindarit encapsulated nanoparticles prevent venous neointimal hyperplasia and restenosis in a murine angioplasty model.
Topics: Angioplasty; Animals; Arteriovenous Fistula; Chromatography, Liquid; Constriction, Pathologic; Disease Models, Animal; Hyperplasia; Indazoles; Mice; Nanoparticles; Neointima; Propionates; Renal Dialysis; Tandem Mass Spectrometry | 2022 |
CCL2 is required for initiation but not persistence of HIV infection mediated neurocognitive disease in mice.
Topics: AIDS Dementia Complex; Animals; Chemokine CCL2; Cognition; Disease Models, Animal; HIV Infections; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Receptors, CCR2 | 2023 |
Upregulated C-C Motif Chemokine Ligand 2 Promotes Ischemic Stroke via Chemokine Signaling Pathway.
Topics: Animals; Brain; Chemokine CCL2; Disease Models, Animal; Humans; Indazoles; Infarction, Middle Cerebral Artery; Locomotion; Male; Neuroprotective Agents; Propionates; Protein Interaction Maps; Rats, Sprague-Dawley; Signal Transduction; Transcriptome; Up-Regulation | 2020 |
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Gene Regulatory Networks; Human Umbilical Vein Endothelial Cells; Humans; Indazoles; Inflammation; Lymph; Lymphatic System; Male; Mesentery; Propionates; Rats, Wistar; Shock, Hemorrhagic; Signal Transduction; Transcriptome | 2020 |
Bindarit Attenuates Pain and Cancer-Related Inflammation by Influencing Myeloid Cells in a Model of Bone Cancer.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinogenesis; Cell Line, Tumor; Chemokine CCL2; Disease Models, Animal; Humans; I-kappa B Kinase; Indazoles; Inflammation; Male; Mice; Mice, Nude; Myeloid Cells; Neoplasms, Experimental; Propionates; Signal Transduction; Tumor Burden | 2018 |
Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Benzoxazines; Brain; Caspase 3; Cells, Cultured; Central Nervous System Depressants; Chemokine CCL2; Disease Models, Animal; Encephalitis; Ethanol; Gene Expression Regulation, Developmental; Indazoles; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurodegenerative Diseases; Propionates; Receptors, CCR2; Signal Transduction; Spiro Compounds | 2018 |
Effects of the MCP-1 synthesis inhibitor bindarit on tumorigenesis and inflammatory markers in the C3(1)/SV40Tag mouse model of breast cancer.
Topics: Animals; Antigens, Polyomavirus Transforming; Biomarkers; Body Weight; Carcinogenesis; Chemokine CCL2; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Indazoles; Inflammation Mediators; Interleukin-6; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Organ Size; Propionates; RNA, Messenger; Spleen; Tumor Burden; Tumor Necrosis Factor-alpha | 2014 |
Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection.
Topics: Adult; Aged; Animals; Bone Density Conservation Agents; Bone Resorption; Chemokine CCL2; Chikungunya Fever; Disease Models, Animal; Female; Humans; Indazoles; Male; Mice, Inbred C57BL; Middle Aged; Propionates | 2015 |
Effects of MCP-1 inhibition by bindarit therapy in a rat model of polycystic kidney disease.
Topics: Animals; Chemokine CCL2; Disease Models, Animal; In Vitro Techniques; Indazoles; Macrophages; Male; Monocytes; Podocytes; Polycystic Kidney, Autosomal Dominant; Propionates; Proteinuria; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; RNA, Messenger | 2015 |
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation.
Topics: Animals; Antibodies; Benzoxazines; Chemokine CCL2; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Indazoles; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Piperidines; Propionates; Receptors, CCR2; RNA, Messenger; Signal Transduction; Up-Regulation | 2016 |
The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice.
Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Disease Models, Animal; Female; Hyperlipidemias; Indazoles; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Propionates; Rats; Rats, Wistar | 2009 |
Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins.
Topics: Alphavirus; Alphavirus Infections; Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Line; Disease Models, Animal; Down-Regulation; Humans; Indazoles; Macrophages; Mice; Mice, Inbred C57BL; Monocyte Chemoattractant Proteins; Muscle, Skeletal; Myositis; Propionates; RNA, Messenger | 2009 |
The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension.
Topics: Animals; Chemokine CCL2; Disease Models, Animal; Fibrosis; Hypertension, Renovascular; Indazoles; Kidney Tubules; NADPH Oxidases; Nephritis; NF-kappa B; Propionates; Receptors, CCR2; Renal Artery Obstruction; Renal Circulation; Sus scrofa; Up-Regulation; Urothelium | 2009 |
Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis.
Topics: Acute Disease; Animals; Ceruletide; Chemokine CCL2; Disease Models, Animal; Indazoles; Inflammation; Mice; Necrosis; Pancreas; Pancreatitis; Propionates | 2005 |